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The US Food and Drug Administration approved two cancer treatments, Vitrakvi and Xospata, this week after expedited reviews.Vitrakvi, approved Monday, is "a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker)."The FDA said in a statement that it is the second approved cancer treatment that is based on a tumor biomarker instead of the place in the body where the tumor originated.Vitrakvi will be used for the treatment of solid tumors that have an NTRK (neurotrophic receptor tyrosine kinase) gene fusion that do not have a known resistance mutation, that are not metastatic or where surgical removal is likely to lead to severe morbidity, and that have no alternative treatments or have progressed after treatments.NTRK genes are rare but occur in many types of cancer, the FDA said, such as mammary analogue secretory carcinoma and infantile fibrosarcoma.Xospata tablets, approved Wednesday, are for the "treatment of adult patients who have relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation," according to the FDA.Alongside the tablets, the agency also approved a diagnostic to detect the mutation."Approximately 25 to 30 percent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in the statement.AML is a rapidly progressing cancer that affects the numbers of normal blood cells and calls for continuous transfusions, the FDA said.Both treatments were granted Priority Review designation.Priority Review, established in 1992, means the FDA aims to review the drug or treatment within six months, opposed to 10 months for a standard review."A Priority Review designation will direct overall attention and resources to the evaluation of applications for drugs that, if approved, would be significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions when compared to standard applications," the FDA says.Both treatments also received?orphan drug?designation, a status granted to drugs for rare diseases or conditions. 2261

The rise in telemedicine could lead to more problems for people who need to keep an eye on their heart health.A study published by JAMA showed televisits accounted for 35% of primary care cases from April to June. Office-based visits declined by half.The study found blood pressure tests also declined by 50% and cholesterol checks went down by 37%.A doctor with the American Heart Association says that could be the result of the uncertainty surrounding the start of the pandemic.“They were doing the COVID tests in the same place as normal labs, so people were hesitant to go, and when you think of cholesterol panel, its fasting, which means a lot of lab places were getting top heavy with people in the mornings,” said Dr. Reshmaal Gomes, a volunteer with the American Heart Association.Gomes says labs now separate COVID-19 tests from other lab work. She says home lab testing has become more efficient and many insurance companies now pay for it.She says telehealth has also proved to be important for those recovering from heart attacks and strokes.“They have shown that telehealth rehab after a stroke is working and working for patients who would not have been able to make those three or four visits to the physical therapist,” said Gomes.Gomes says people who had blood pressure and cholesterol checks done in between doctor visits reduced their likelihood of a heart related emergency by 50%. 1412

The terror attack on New York City's West-Side bike path has President Trump calling for congress to eliminate the "Diversity Visa" program.Congress created it in 1990. It was signed into law by President George W. Bush.Among the San Diegans who are here because of the visa program is Anna Riazanova.In 1993, Riazanova, a native of Russia, entered the U.S. on a student visa and began studying to become a paralegal."I fell in love with the country, the people," said Riazanova.A year later, she applied for the Diversity Visa Lottery program, aimed at diversifying immigration by randomly selecting 50,000 green card applicants every year from countries with historically low U.S. immigration rates. 709

The search for a 12-year-old thought to be trapped in a Mexico City elementary school ended Thursday with the news that all students have been accounted for.But rescuers will continue their work, as signs suggest that someone may still be alive in the rubble, Angel Enrique Sarmiento, Mexico's sub-secretary of Navy, said Thursday.For days, Colegio Enrique Rebsamen was the site of a massive search and rescue operation offering a glimmer of hope in the chaotic aftermath of Tuesday's magnitude 7.1 quake. Reports of the missing 12-year-old riveted people across the country, who watched the rescue efforts unfold live on television. 656

The woman had used oxycodone for almost a decade but told her doctors she had been sober for two years. She never touched narcotics during her pregnancy, she said, and had completed rehab.But her newborn son was in withdrawal: jittery, screaming and requiring an infusion of morphine to stay alive. The infant craved drugs, but why?Amid an opioid epidemic, the boy's doctors didn't blame heroin, fentanyl or other illicit substances. Instead, they said, the infant had grown dependent on a controversial herbal supplement: kratom. 538

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