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A large fire broke out early Friday at a refinery in Philadelphia, the city fire department told CNN.The fire started at Philadelphia Energy Solutions between 3 and 4 a.m., according to CNN affiliates.Residents reported several explosions that were felt in South Jersey and Delaware County, Pennsylvania, according to CNN affiliate 344

A lot happened in 2018, but perhaps what social media users noticed most was the uptick of racist and hate-fueled incidents dominating their newsfeeds.Here a sampling of some of the incidents, ranging from racism to bullying to being just plain mean, that went viral in 2018."White" and "colored" water fountainsA Wisconsin high school student was disciplined after 379

A family-owned bakery declined to sell a wedding cake to a gay couple over the weekend, citing the "spiritual conviction" of the owner.The bakery, Susie's Sweets, lists its location on 197

A federal judge in California ruled against the Trump administration on Friday in two different cases, ultimately preventing .5 billion in federal funds from being used for a border wall in portions of California, New Mexico, Texas and Arizona.In the first case, US District Court for Northern California ruled in favor of a challenge to President Donald Trump's attempt to move billions from the Defense Department budget toward building a border wall in El Centro, California, and New Mexico.Trump's move was done as part of his national emergency declaration in February. California Attorney General Xavier Becerra filed the lawsuit, joined by 16 states, soon afterward.Becerra celebrated the ruling Friday, which he said permanently stops the administration from proceeding with construction on the wall."These rulings critically stop President Trump's illegal money grab to divert .5 billion of unauthorized funding for his pet project," Becerra said. "All President Trump has succeeded in building is a constitutional crisis, threatening immediate harm to our state. President Trump said he didn't have to do this and that he would be unsuccessful in court. Today we proved that statement true."CNN has reached out to the White House for comment.Judge Haywood Gilliam determined in the 1308

A Denver family is trying to raise million in order to cure their son with a rare genetic disease. Doctors told Amber Freed that her 2-year-old son is one of 34 people in the world to have this rare neurological genetic disease. “The disease is so rare, it doesn’t even have a name,” Freed said. “It’s called SLC6A1, because that is the gene that it effects.” The disease causes Maxwell to have trouble moving and communicating, and soon it will only get worse. “The most debilitating part of the disease will begin between the ages of 3 and 4,” Freed said. “So, we are in a fight against time.”Maxwell has a twin sister named Riley. “I noticed early on that Maxwell wasn’t progressing as much as Riley,” Freed said. “I noticed he couldn’t use his hands. The doctors told me that every baby can use their hands. That’s when I realized there was something wrong with him.”After multiple visits to the doctor, Freed was able to find a genetic specialist to give Maxwell a diagnosis. “He looked at me and said, ‘Something is very wrong with your son. I don’t know if he’s going to live,’” Freed said. “My soul was just crushed. It was a sadness I didn’t even know existed on earth. You never think something like this could happen. I left my career, and I had no other choice but to create my own miracle and to find a treatment forward to help Maxwell and all those others like him.” Freed searched for scientists trying to create a cure, which she found at the University of Texas Southwestern Medical Center in Dallas. “We’re working with diseases where kids are born with a defective gene,” said Steven Gray, an associate professor at UTSW in pediatrics. “Our approach is to replace that gene to fix the condition at the level of their DNA. We’re taking the DNA that those patients are missing and packaging that into a virus and use that virus as a molecular delivery truck to carry those genes back in their body and fix their DNA.” “It’s a rare disease, no one has ever heard of it,” Freed said. “But one rare disease messed with the wrong mother.” Freed said she has raised million to help with research for the cure and will need an additional million, in order to let Maxwell and many others continue to enjoy life. “I want Maxwell to have every opportunity that children should have in this life,” Freed said. “When he is having a good day, I just try and soak him in as much as I can. We don’t take anything for granted in this house.” If you want to help donate for the cure, you can do so by visiting 2535