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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597
The House Judiciary Committee will request documents on Monday from President Donald Trump's oldest son, his business and more than 60 individuals in his administration, the panel's chair said Sunday.In an interview with ABC News' "This Week," Rep. Jerry Nadler said the requests for documents are to "begin investigations, to present the case to the American people about obstruction of justice, about corruption and abuse of power."The New York Democrat said the full list of individuals and entities would be released Monday, but he mentioned Donald Trump Jr. and Trump Organization Chief Financial Officer Allen Weisselberg.Nadler also said the list would likely include former White House chief of staff John Kelly and former White House counsel Don McGahn."Impeachment's a long way down the road," said Nadler, whose panel would begin any impeachment process. "We don't have the facts yet, but we're going to initiate the proper investigations."Asked if he thought President Trump had obstructed justice, Nadler replied, "Yes, I do. It's very clear that the President obstructed justice."Since taking power in the wake of November's midterm elections, House Democrats have vowed to investigate Trump's presidency and business as they await the special counsel Robert Mueller investigation's findings.As special counsel Robert Mueller wraps up his Russia probe, federal investigators have focused on conflicting public statements by President Trump and his team that could be seen as an effort to influence witnesses and obstruct justice, people familiar with the investigation told CNN.Critics pointed to the President's firing of then-FBI Director James Comey in 2017 as a potential obstruction of justice, as Trump told NBC News he was thinking about the Russia investigation when he decided to remove Comey.Besides Comey's firing, prosecutors appear to be examining Trump's role in crafting the misleading Air Force One statement in 2017 on the now-infamous June 2016 Trump Tower meeting with Russians attended by Trump Jr.Another episode centers on Trump's attempt to have his then-White House counsel McGahn dispute news reports that he threatened to quit over Trump's pressure to oust Mueller, CNN previously reported.Weisselberg was granted immunity in August by federal prosecutors for providing information on former Trump attorney Michael Cohen's role in hush money payments to women alleging affairs with Trump. He has repeatedly denied having affairs with the women.But Cohen's hearing before the House Judiciary Committee last week piqued congressional Democrats' interest in hearing from Weisselberg, as Cohen said the Trump Organization official had insight into Trump's tax filings. 2716

Terrorism is an age-old concept.Some people think the first attack happened in the first century against Roman collaborators.But modern terrorism is thought to come out of mid-19th century France, when good-quality, affordable explosives hit the market and radical political movements became more prominent.It came to the U.S. during the same time frame.Today, the terrorism landscape is much different, and so is the response.The FBI says its No. 1 priority is protecting the U.S. from terrorist attacks, regardless of motivation.Terrorism investigations fall into two categories at the FBI: international terrorism and domestic terrorism.The first is when an attack is inspired by or associated with foreign organizations or nations.If the attack or attacks are meant to further a domestic influence’s goals, it’s domestic terror.The FBI’s examples of domestic terror motivations include politics, religion, race and social issues.Domestic terror “remains persistent” overall, according to the FBI.The FBI says people cross the line from exercising First Amendment freedoms to committing crimes in hopes of furthering violent agendas.Terrorism has evolved immensely since 9/11.The FBI says lone offenders and the internet have accelerated that evolution.According to the FBI, lone offenders are tougher to identify and stop because they aren’t always clearly tied to a group.And the internet — social media, in particular — helps terrorists connect with potential recruits more easily.To meet the evolving threat, law enforcement is constantly changing its approach. 1580
The Dow tumbled more than 950 points at one point on Monday and global stocks were in disarray after China escalated the trade war with the United States.The Dow finished down 767 points for the day. The Chinese government devalued the yuan to fall below its 7-to-1 ratio with the US dollar for the first time in a decade Monday. A weaker currency could soften the blow the United States has dealt China with its tariffs.The weak yuan ignited fear on Wall Street that a currency war has begun or that the United States would respond with even higher tariffs, prolonging the standoff with China and potentially weakening the global economy. Investors are particularly concerned that the Trump administration could try to devalue the dollar, sparking a currency war that could weaken Americans' purchasing power."Risks of Trump intervening in foreign exchange markets have increased with China letting the yuan go," wrote Viraj Patel, FX and global macro strategist at Arkera, 987
The body of Nevaeh Adams, a 5-year-old South Carolina girl who went missing in August, was found on Friday, the Sumter Police Department announced on Tuesday. Police used DNA to confirm the body found was Nevaeh's. Nevaeh's mother, Sharee Bradley, was also killed. Bradley's body was found on Aug. 5 in her apartment by a family member.The suspect, Daunte Johnson, has admitted to killing Bradley and her daughter, police say. Johnson told police that he put Nevaeh's body in a dumpster. Approximately 400 individuals from more than 40 agencies searched about 4 million pounds of material, Sumter Police said. Nevaeh had two other siblings, ages 3 and 12, who were unharmed. 687
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