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YOKOHAMA, Japan — Two passengers taken off the Diamond Princess, a cruise ship quarantined off the coast of Japan, have died after contracting COVID-19, according to Japan's Health Ministry. The ministry says the man and woman passed away as a result of the coronavirus on Thursday. They were Japanese, in their 80s and had preexisting diseases. 358

(AP) - With CBD showing up everywhere, U.S. regulators announced Tuesday they are exploring ways the marijuana extract could be used legally in foods, dietary supplements and cosmetics.The U.S. Food and Drug Administration said it will hold a public hearing May 31 to gather more information on the science, manufacturing and sale of cannabis compounds like CBD.In the meantime, it issued more warning letters to companies for making unapproved health claims about CBD products.Products containing CBD are already in stores and sold online, so it's easy to believe there must be something special about the ingredient. But the claims are largely unproven and quality control standards don't exist.RELATED: Can using CBD products cost someone their job? A look at what we know as U.S. regulators work out what will and won't be allowed:WHAT IS CBD?CBD is one of more than 100 compounds found in marijuana. It's extracted using alcohol or carbon dioxide in factories. It's added to oils, mixed into creams and lotions and sold in candies and liquid drops.Widely sold online, CBD now is going mainstream with major retailers offering salves and balms for the skin. Prices range from to 0 an ounce at high-end shops.CBD often comes from a cannabis plant known as hemp, which is defined by the U.S. government as having less than 0.3 percent THC. That's important because THC is what causes marijuana's mind-altering effect.CBD doesn't get people high, although it may be calming. Keep in mind some CBD products may contain THC, whether or not the label says so.RELATED: CBD-infused foods become rising trend in 2019People drug tested for work, addiction programs or because they take prescription opioids should take note: CBD products have caused people to fail urine drug screens.IS IT A MIRACLE CURE?If you believe the hype, CBD treats pain, relieves anxiety and both helps you sleep and keeps you focused.Most claims are based on studies in rats, mice or in test tubes. Some human research has been done, but in small numbers of people.One exception: For two rare seizure disorders, the evidence for CBD was strong enough to convince the FDA to approve GW Pharmaceutical's drug Epidiolex, which contains a purified form.The FDA announced Tuesday it has sent warning letters to three companies marketing products with what outgoing Commissioner Scott Gottlieb called "egregious, over-the-line claims" for CBD's effects on cancer, Alzheimer's disease, fibromyalgia and drug addiction. Gottlieb said the agency "won't tolerate this kind of deceptive marketing to vulnerable patients."RELATED: CVS Pharmacy selling cannabis-based products in stores in California, 7 other statesOnly drugs that have been reviewed by the FDA as safe and effective can make claims that they treat or prevent diseases or medical conditions. Many CBD producers attempt to sidestep the issue by using only vague language about general health and well-being.ANY SIDE EFFECTS?Scant research means not much is known about side effects either. In epilepsy research, CBD changed the way the body processed other drugs. That suggests CBD could interact with medications in ways we still don't know about.The most common side effects of the CBD drug Epidiolex include sleepiness, decreased appetite, diarrhea, increases in liver enzymes, exhaustion, rash and infections. FDA's Gottlieb noted Tuesday the potential for liver injury and other risks can be handled with medical supervision but less is known about how that would be managed without oversight. And there are questions about overlap if multiple CBD products are used.IS IT LEGAL?For now, the agency has said CBD is not allowed as an ingredient in food, drinks or dietary supplements.In stating its position, the FDA cited a provision of the law prohibiting food makers from using active drug ingredients or those that are the subject of substantial research. But the agency doesn't have the resources to police all the CBD products that are already available, said Marc Scheineson, a former FDA official.RELATED: Creator of Jelly Belly releases CBD-infused jelly beans"They're not going to pull a thousand products from the market," he said.The FDA's authority is over interstate commerce, and local officials have taken differing approaches. In New York, Los Angeles and elsewhere, officials are warning eateries to stop selling it in food and drinks. Maine passed a law allowing it in foods and other products in the state.Skin creams and cosmetics may be on safer footing with the FDA, but that too remains uncertain, said Camille Gourdet of RTI International, a nonprofit research institute in Durham, North Carolina. Though cosmetics aren't subject to premarket approval by the FDA, they could run afoul of regulations if they make specific health claims.Marijuana itself is illegal under federal law; most states that have legalized it allow marijuana-infused foods and candies, called edibles.ARE CBD LABELS ACCURATE?What you buy may contain much less CBD than the label states — or much more. It may include more THC than you want and it may be contaminated with mold or pesticides. Ask to see testing reports.A 2017 study in the Journal of the American Medical Association found 70 percent of CBD products were mislabeled. Researchers used an independent lab to test 84 products from 31 companies."You're really flying by the seat of your pants when you buy this stuff," said author Marcel Bonn-Miller of University of Pennsylvania.A product labeled as containing 100 milligrams of CBD may only have 5 milligrams or it may have 200, said Bonn-Miller, now an adviser for a company that sells CBD and other cannabis products. He did not work in the industry when he did the research."I wouldn't trust any of it until I knew independently it was safe," Bonn-Miller said.WHAT'S AHEAD?CBD research is planned or underway for cancer, autism, diabetic neuropathy, fibromyalgia, chronic pain, alcoholism with PTSD and psychiatric conditions. Results will take years, but some people aren't waiting."They are vulnerable and really hoping to feel better," said Karen Hande, a nurse practitioner at Vanderbilt-Ingram Cancer Center in Nashville.She became an expert in CBD because so many of her cancer patients were trying it. She tells them the evidence isn't enough to back the claims, but "they want to believe something is going to work." 6383

 Special counsel Robert Mueller's team on Friday slammed a suggestion by Michael Flynn's lawyers last week that President Donald Trump's former national security adviser lied to the FBI not even a month into his tenure because he was caught off guard when two agents approached him.However, Mueller's office said it would not change its recommendation that Flynn receive no jail time, given he has accepted responsibility for his actions and cooperated with the special counsel.Mueller on Friday also released memos written by the FBI agents, and emphasized that when Flynn lied to them on January 24, 2017, about the substance of his policy conversations with then-Russian Ambassador Sergey Kislyak, he had already lied to several members of Trump's team and was "committed to his false story" that he and Kislyak did not discuss sanctions.Flynn later said he had lied, and will be sentenced next week. 916

(CNN) -- A Michigan lottery winner must share the million windfall with his ex-wife, even though they were in the process of divorcing when he bought the ticket.Richard Zelasko won an million Mega Millions jackpot in July 2013 -- after taxes and fees his prize was ,873,628, according to an opinion issued last week by the Michigan Court of Appeals.The suburban Detroit man and his then-wife, Mary Elizabeth Zelasko, filed for divorce in late 2011. The case had gone to arbitration, and they were waiting for the arbitrator's opinion when Richard Zelasko won the prize.The couple were married in 2004 and have three children.The arbitrator ruled that the ticket was part of the couple's marital assets and awarded million to the wife and divided the rest of their assets, according to the opinion. He said that the "marital property includes all property acquired from the date of marriage until the date of entry of the divorce decree," including property acquired during a separation.The court also cited the arbitrator's opinion that the winning lottery ticket was probably not the first that Richard Zelesko had purchased during the marriage and that "(a)s losses throughout the marriage were incurred jointly, so should winnings be shared jointly."It's true that Zelasko spent to buy the winning ticket; however, "the dollar spent was arguably marital money and, as such, a joint investment," the arbitrator said.The appellate court said it found no errors that would require it to change the award."It's very difficult to overturn an arbitration," said Michael Robbins, who's represented Richard Zelasko since 2015.Robbins told CNN that the couple had been separated since 2009.An attorney for Mary Elizabeth Zelasko told CNN that he would not comment on the case because it is confidential.The couple's divorce was finalized in 2018.Robbins said his client can appeal the ruling and is "considering his options." 1945

(AP) -- For months, California’s skilled nursing facilities have been shut down to visitors to keep out the coronavirus. State health authorities recently issued guidance for visits to resume, but few are happening as infection rates surge in California.Facilities are being cautious after many suffered severe outbreaks earlier in the pandemic. Nursing facilities account for about 40% of California's roughly 7,000 coronavirus deaths. Families have relied on phone and video calls to stay in touch with loved ones. An administer at a skilled nursing facility in Berkeley says she doesn't want to proceed with most visits until getting approval from the city. 669

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