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WASHINGTON, May 11 (Xinhua) -- Johns Hopkins University researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.The work, published Wednesday in the journal Science Translational Medicine, suggests that liver cells derived from so- called "induced-pluripotent stem cells (iPSCs)" could one day be used as an alternative to liver transplant in patients with serious liver diseases, bypassing long waiting lists for organs and concerns about immune system rejection of donated tissue."Our findings provide a foundation for producing functional liver cells for patients who suffer liver diseases and are in need of transplantation," says Yoon-Young Jang, assistant professor of oncology at the Johns Hopkins Kimmel Cancer Center. "iPSC-derived liver cells not only can be generated in large amounts, but also can be tailored to each patient, preventing immune-rejection problems associated with liver transplants from unmatched donors or embryonic stem cells." A microsopic view shows human embryonic stem cells in various stages of differentiation into liver cells in this photo taken at Stanford University and released by the California Institute for Regenerative Medicine, March 9, 2009iPSCs are made from adult cells that have been genetically reprogrammed to revert to an embryonic stem cell-like state, with the ability to transform into different cell types. Human iPSCs can be generated from various tissues, including skin, blood and liver cells.Although the liver can regenerate in the body, end-stage liver failure caused by diseases like cirrhosis and cancers eventually destroy the liver's regenerative ability, Jang says. Currently, the only option for those patients is to receive a liver organ or liver cell transplant, a supply problem given the severe shortage of donor liver tissue for transplantation. In addition, mature liver cells and adult liver stem cells are difficult to isolate or grow in the laboratory, she says. By contrast, iPSCs can be made from a tiny amount of many kinds of tissue; and the embryonic stem- like iPSCs can grow in laboratory cultures indefinitely.For the study, Jang and colleagues generated human iPSCs from a variety of adult human cells, including liver cells, fibroblasts ( connective tissue cells), bone marrow stem cells and skin cells. They found that though the iPSCs overall were molecularly similar to each other and to embryonic stem cells, they retained a distinct molecular "signature" inherited from the cell of origin.

SAN FRANCISCO, April 5 (Xinhua) -- Apple Inc.'s iPad 2 has topped the ratings by Consumer Reports, an influential U.S. magazine for product reviews, in the latest tests of the 10 most- promising tablet computers.According to the ratings released on Tuesday, the Apple iPad 2 with Wi-Fi plus 3G (32G), which is priced at 730 U.S. dollars, topped the ratings, scoring "excellent" in nearly every category.Besides several models from Apple, other brands tested include Archos, Dell, Motorola, Samsung and Viewsonic. Each tablet was evaluated on 17 criteria, including touch-screen responsiveness, versatility, portability, screen glare and ease of use."So far, Apple is leading the tablet market in both quality and price, which is unusual for a company whose products are usually premium priced," Paul Reynolds, electronics editor at Consumer Reports, said in a statement.The Motorola Xoom, whose price is 800 dollars, stood out as the iPad 2's main rival. It boasts several features that the iPad lacks, including a built-in memory card reader and support for the Flash videos.The first-generation iPad, priced at 580 dollars, also outscored many of the other models tested but tied with the Motorola Xoom, according to tests by Consumer Reports.

SANAA, Feb. 6 (Xinhua) -- In response to earlier reports that a Chinese-flagged commercial ship was hijacked by Somali pirates off Yemeni coast, the China Maritime Search and Rescue Center (MSA) said Sunday that the ship has never been hijacked, and is now sailing safely with escort of the Chinese anti-piracy navy fleet.Both the "Tien Hau" ship, which was registered in Hong Kong, China, and its 22-member crew, are safe, a MSA official confirmed to Xinhua over the phone. The center contacted the ship to make sure it was safe, he added.The ship had been followed by a suspicious boat for a while, but it was never attacked or hijacked, the official said.Earlier, Yemeni Interior Ministry had said the ship was hijacked by pirates some 20 kilometers off the Yemeni island of Al-Tair off the city port of al-Hudaida, and was heading to Somali coast.The Gulf of Aden is considered as one of the world's most dangerous waters because of rampant piracy.

MOSCOW, Jan. 21 (Xinhua) -- Russian and Chinese companies started construction of an iron ore dressing plant Friday in the Evreyskaya Autonomous Oblast to provide high-grade iron ore to the Asia Pacific region, including China.Yury Makarov, chief executive officer of IRC Ltd., told Xinhua the plant would reach its designed capacity in 2013 at 10 million tons of iron ore and 3.2 million tons of iron ore concentrates, which contain up to 65 percent iron.Makarov said that 20 percent of the iron ore concentrates, which are natural iron ore processed through crushing, grinding and dressing, would be used to meet demands of Russia's far east and the rest would go to the Asia-Pacific market. Currently, China imports large amounts of concentrates from Brazil, Australia and India."We are very open to interaction with various countries of the Asia-Pacific region, especially China. The volume of processed iron ore has been increasing every year. We will be happy to deliver iron ore to your companies as well as any other consumers who are willing to purchase our products," he said.The plant will draw its resources from the Kimkanskoye and Sutarskoye deposits and send its products through the Khabarovsk Krai and the Suifenhe port to China.The plant is only 7 km from the Trans-Siberian Railway. A railway bridge is being planned between Evreyskaya Oblast and Heilongjiang to further shorten the supply route.Total investment in the plant is 400 million U.S. dollars, with 340 million in loans from the ICBC (Industrial and Commercial Bank of China) in China. Interest under the facility will be charged at 2.8 percent above LIBOR per annum. The China National Electric Engineering Co, Ltd is tasked with the construction of the plant.Makarov said he was very optimistic about the future of the plant and the development of relations between the Russia's far east and China's northeastern region.IRC Ltd. is a metal unit of Russian gold miner Petropavlovsk PLC. It became the second Russian company to be listed on the HK stock exchange, when it started trading on Oct. 21.

BEIJING, May 16 (Xinhuanet) -- NASA has readied the space shuttle Endeavour for its liftoff set for Monday, media reported Monday.Good weather looks 70 percent likely for Monday's scheduled launch of Endeavour, the next-to-last U.S. space shuttle mission as NASA develops a new generation of craft for longer voyages."The updated forecast Sunday for Monday's launch of the shuttle Endeavour remains unchanged with a 70 percent chance of good weather," said NASA spokesman Allard Beutel.The space shuttle Endeavour STS-134 sits on launch pad 39A after the rollback of the Rotating Service Structure at the Kennedy Space Center in Cape Canaveral, Florida May 15, 2011.Liftoff is set for 8:56 a.m. EDT (1256 GMT) from the Kennedy Space Center for the trip to the International Space Station after the U.S. space agency repaired a technical glitch that canceled last month's launch attempt.The initial April 29 launch attempt was scrubbed hours before liftoff when technicians discovered a power failure in a heating line that served to prevent fuel from freezing in orbit.The six-member crew of astronauts including five Americans and one Italian, Roberto Vittori, will deliver a potent physics experiment to probe the origins of the universe during the mission, which will include four spacewalks.The 16-day mission is intended to help get the space station ready for operations after the shuttle fleet is retired. The 135th and final shuttle launch is scheduled for early- to mid-July aboard Atlantis.