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Today Unique Edwards met her plasma donor Chris Klug. Unique, a mother, battled COVID-19 and said without the plasma donation, she believes she wouldn’t have made it. pic.twitter.com/YBmg55KAWM— Adriana Mendez (@AdrianaMendez) October 13, 2020 257

Thursday marks exactly six months since the World Health Organization (WHO) declared a global health crisis connected with the disease that was then simply known as the novel coronavirus.Half a year later, the virus has infected 17 million people on every continent and killed more than 600,000 worldwide.On Jan. 31, WHO issued a statement saying that Dr. Tedros Adhanom, the director-general of the organization, had accepted a committee's recommendation to declare the outbreak of the virus in China a "public health emergency of international concern."At the time, the outbreak was mainly concentrated in China, as the country had confirmed 7,711 cases of the virus and 170 deaths linked to the disease. While the virus had been recorded in five other countries — including five cases in the U.S. — there had been no deaths recorded outside of China.In its Jan. 31 declarations, the WHO did not recommend any travel or trade restrictions, but urged countries to prepare for containment and "place emphasis on reducing human infection, prevention of secondary transmission and international spread."The organization issued its recommendation 10 days after China reported that the virus appeared to be spreading from person-to-person, a finding that indicated the disease could have far-reaching implications. The New York Times reports that by that time, thousands had traveled out of Wuhan, the virus' place of origin, possibly spreading it around the world. China has since faced criticism for not reporting its findings sooner.That same day, President Donald Trump took action to block entry into the U.S. of any person that had been in China for the last 14 days. The order did not apply to U.S. citizens. While the move may have temporarily delayed the virus' widespread arrival, his administration's inaction for the next month would prove costly.During the next month, the CDC would face significant delays in developing a test for COVID-19, which would cause a testing backup in the months to come. The president also repeatedly downplayed the severity of the situation, declaring on Feb. 26 that the number of cases in the U.S. would go down to zero in the coming days.In the months since the WHO's declaration, 150,000 Americans have died of COVID-19, and more than 4 million have been infected. Both figures are by far the most of any other country. 2370

This Thanksgiving is shaping up to be like no other.With the U.S. experiencing a spike in COVID-19 cases, the Centers for Disease Control and Prevention (CDC) is advising Americans to celebrate turkey day with the people they live with, as opposed to traditional feasts with extended family and friends.With many people celebrating the holiday is small groups, it may be easier and more cost efficient to order takeout or ready-made meals this year.Not only could ordering in save you money and work, it may also serve as an opportunity to support the restaurant industry that has been hit so hard by the pandemic, especially small establishments. The business could help them make up for lost revenue. A survey released by National Restaurant Association in September found that 1 in 6 restaurants was closed either permanently or long-term, nearly 3 million workers were out of work, and the industry was on track to lose 0 billion in sales by the end of 2020.There are endless options for takeout for your Thanksgiving meal. You could celebrate with any cuisine, but if you want to stick to traditional foods, some national chains are offering turkey day dinners. Here are a few:Denny’s – The restaurant is offering a family-style “Turkey & Dressing Dinner Pack” that can be picked up until 6 p.m. on Wednesday, Nov. 25.Cracker Barrel – Like in years past, the chain is offering meals for gatherings of all sizes, including its “Thanksgiving Heat n’ Serve Family Dinner.”Boston Market – This chain may also be an option, as it serves up plated meals, family meals, whole pies and hot side dishes.Offers.com also compiled a list of more than 30 restaurant chains that are open on Thanksgiving.Regardless of where you order from, consider leaving a tip for the restaurant employees who are not only working on Thanksgiving, but also in the midst of a pandemic. 1876

This Labor Day, gas prices are set to be the lowest since 2004.According to AAA, the national average is .23, which is down 34 cents from last year.Gas Buddy reported the national average for the lowest-priced gas price on Labor Day was .82 per gallon in 2004.AAA said car trips are down 3% from last year, with air travel being down 75%."That means that motorists should expect heightened traffic throughout the Labor Day holiday, on top of new restrictions and precautions necessitated by the current health challenge," AAA said in a press release.AAA says prices at the pump will continue to drop in the coming weeks, as "demand falls and refineries in the Gulf of Mexico region come back online in the wake of Hurricane Laura." 743

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

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