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The Trump Administration pushed through a million contract to study whether the active ingredient in Pepcid is an effective treatment for Covid-19. That contract is now under scrutiny after a government whistleblower accused a senior administration official of rushing the deal through without the scientific oversight necessary for such a large federal award. The Food and Drug Administration gave the clinical trial speedy approval even as a top agency official worried that daily injections of high doses of famotidine for already sick patients pushed the levels of what was considered safe “to the limits,” internal government emails show. And the doctors who initially pushed the Pepcid idea are locked in a battle for credit and sniping over allegations of scientific misconduct.The origins of the interest in famotidine are under dispute, but there were reports out of China that patients who took the drug survived the virus, while patients who took other heartburn medications were not surviving. Initial observational studies in the U.S. were promising, however scientists urged more research was needed. Meantime, the trial itself that was part of the million contract is on pause due to a shortage of hospitalized COVID-19 patients in New York, delaying it indefinitely. A vaccine or effective treatment could be available before the study is complete. 1380

The US Postal Service is asking for the biggest price jump on stamps in its history.Facing pressure from the Trump administration to address a revenue shortfall, the Postal Service on Wednesday proposed raising the price of 1-oz. letters from 50 cents to 55 cents, which would be a record nominal increase if approved. The price of each additional ounce would go down slightly.The request was made by the USPS' board of governors, which has been operating on an emergency basis?because of a lack of confirmed members. It will have to be approved by the Postal Regulatory Commission."The Governors believe these new rates will keep the Postal Service competitive while providing the agency with needed revenue," the USPS said in a press release. "The Postal Service has some of the lowest letter mail postage rates in the industrialized world and also continues to offer a great value in shipping."Rates for mailing services -- which includes catalogs and magazines as well as letters -- are pegged to consumer prices. Those have been rising faster this year, but still limited the price hike for that category to 2.5 percent.Prices for packages, however, can float with market rates. The USPS wants to boost Priority Mail prices by an average of 5.9%. A small flat-rate box that costs .20 to ship, for example, would next year cost .90.The steep price increases come at a time when the USPS' losses have been mounting, dragged down in part by a requirement that the quasi-public agency pre-fund the cost of retiree health benefits.As letters and advertising mailers have been replaced by e-mail and online ads, the USPS has been making less and less money. Revenue from first-class mail declined from .4 billion in fiscal year 2015 to .6 billion in 2017.Package revenues fueled by the rise in e-commerce have been a bright spot, bringing in .5 billion in 2017, up from billion in 2015. But it hasn't made much of a dent in the .7 billion net deficit that the Post Office has accumulated over the years.The White House has proposed privatizing the Post Office, a plan that postal unions protested in nationwide demonstrations on Monday.President Donald Trump has repeatedly criticized the terms of USPS' contract to deliver Amazon packages, the details of which are confidential. The Postal Service says it makes a profit through the arrangement."Why is the United States Post Office, which is losing many billions of dollars a year, while charging Amazon and others so little to deliver their packages, making Amazon richer and the Post Office dumber and poorer?" Trump tweeted last December. "Should be charging MUCH MORE!"In April, Trump ordered a review of the Postal Service's business model by a task force led by the Treasury Department. Postal Service spokesman Carl Walton says the review has been completed, but that the agency hasn't seen it yet."I think they're waiting until after the elections," Walton said. "We're waiting just like everybody else." 3041

The walk to school turned terrifying for a Rochester, Michigan teen who says he was shot at after he stopped to ask for directions.Fourteen-year-old Brennan Walker missed the bus and tried to walk to school, but got lost after he couldn't remember the route.The freshman wasn't hit, as the shot missed him as he ran away.The situation began when Walker's alarm didn't go off. After missing his bus, he thought he could walk the roughly 4 miles to school.Once he became lost, he stopped at a home and knocked."I knocked on her door a few times and she came down yelling at me before I could say anything and she thought I was trying to break into her house," he said. "I was trying to explain to her that I wanted to get directions to go to my school. I told her no, I go to Rochester High I’m just looking for directions to Rochester High."Walker and his mother, Lisa, say the security video from the home shows the woman then yelled for her husband."The man of the house came down, pretty much just grabbed the shotgun to shoot at my son," says Lisa Walker."I saw it. I saw him holding it like this through the window and I guess I put my hand up, I don’t really remember, and I started to run," Brennan Walker says. "I looked back behind me I saw him aiming at me and I turned back. I turned back and I heard the gunshot. And I tried to run faster."The man has been taken into police custody."If someone is running from your house and chase them outside and shoot at them, you’re going to have criminal charges coming from us," Oakland County Sheriff Michael Bouchard said.Both Walker and his mother believe race was a factor in the incident."After watching the video and hearing the wife say 'why did these people choose my house' I knew it was racially motivated. I don't know what other these people she could possible have been talking about. He was by himself," Lisa Walker said."I didn’t want to believe that that type of stuff could happen here," said Brennan, who said he is just trying to process the shock of what happened."I don't, I don't know how you process getting shot at for asking for directions," he says. 2159

The United States could see an increase in immigrants coming to the country after Hurricanes Irma and Harvey, according to new research from the University of Michigan.According to the study, there are multiple reasons this happens, including migrants might find it easier to flee destruction in their own country.Another reason, according to U-M economists Dean Yang and Parag Mahajan, is they are able to secure green cards or legal permanent residency through their families already established in the country."When there's a bigger stock of previous migrants to the U.S., when someone in their home country is more likely to have a connection to some sort of migrant in the U.S., then the effect of hurricanes on migration is larger," Yang said.The researchers first studied the severity of a hurricane in a given country, using data from meteorological reports to estimate actual damage.Yang and Mahajan then analyzed restricted U.S. Census data from 159 counties over 25 years to see if America saw a rise in immigration following large storms in other countries.The largest effect came from Central America and the Caribbean."These regions get hit a lot by hurricanes that cause severe damage, and there are a lot of Central American and Caribbean immigrants in the U.S., so if you're looking for someone to sponsor you, you actually have that opportunity," Mahajan said.One example of that is Hurricane Cesar hitting Nicaragua in 1996. It caused food shortages, .5 million in damage, left 100,000 people homeless and killed 42. Yang and Mahajan found that in 1996 and 1997, there was a 50 percent increase in legal permanent residencies for Nicaraguans than in 1995."Much of this increase came from immediate relatives of U.S. citizens - parents, spouses and children," Mahajan added. "Repeated, similar responses like this in the data helped us conclude that networks of U.S. citizens from sending countries provide opportunities for family members to escape severe weather events." 2007

The Supreme Court cleared the way on Monday for states to legalize sports betting, striking down a 1992 federal law that had prohibited most states from authorizing sports betting.The 6-3 ruling is a victory for New Jersey and other states who have considered allowing sports gambling as a way to encourage tourism and tax revenue. The NCAA, NFL and NBA had backed the federal prohibition.The court said the federal law violated constitutional principles limiting the federal government from controlling state policy, unconstitutionally forcing states to prohibit sports betting under their own laws. 608