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LONDON (AP) — Oxford University says trials of a coronavirus vaccine that it is developing with pharmaceutical company AstraZeneca will resume, days after being paused due to a reported side-effect in a patient in the U.K. The university said in large trials such as this “it is expected that some participants will become unwell and every case must be carefully evaluated to ensure careful assessment of safety.” It said globally 18,000 people have received the vaccine so far. Oxford insisted that it is “committed to the safety of our participants.” Pauses in drug trials are commonplace. The Oxford-AstraZeneca vaccine is seen as one of the strongest contenders among the dozens of coronavirus vaccines being tested. 728

LOS ANGELES (CNS) - Gov. Gavin Newsom said Monday he understands the frustrations of people who have been protesting police brutality across the state, but he lashed out at those who are taking advantage of the unrest to engage in looting.Newsom also declined to directly respond to comments made by President Donald Trump in a conference call with the nation's governors Monday morning, in which the president called many of their responses to protests "weak.""I have a choice. We all have a choice," Newsom said. "I can be part of the daily back and forth in the news cycle, and to continue to perpetuate the problems that persist in this country. I can choose to go back and forth and just be another voice in that cause. Or I can choose to focus a message that I think is so much more powerful that I hope has more resonance for people watching, and that is I care more about them than some of the noise I heard on a morning phone call."RELATED: Looters smash windows, rob stores in downtown San DiegoNewsom expressed solidarity with protesters and their call for change in a system that has failed communities for generations."The black community is not responsible for what's happening in this country right now. We are," he said. "Our institutions are responsible. We are accountable to this moment."RELATED: La Mesa community comes together to clean up downtown after Saturday riotsBut he said he had no patience for those who are taking advantage of the protests to engage in lawlessness."When you're out there to exploit conditions, not advance the cause of justice -- that is not serving the greater good," he said. "And we need to also call that out. The looting, the violence, the threats against fellow human beings -- that has no place in this state and in this nation. We as a society need to call that out."RELATED: San Diego County law enforcement denounce George Floyd's deathHe said another 1,100 members of the National Guard have been called up to assist cities across the state cope with the protests and violence, bringing the total to about 4,500. But he said the state and nation as a whole need to do more than just respond to the protests on the streets."We are committed and resolved to bringing peace back to the streets, not only in the state but supporting efforts all across this nation," he said. "But it's not just a situational moment. we have to focus on the medium and long-term and we have to prove our commitment and our resolve in that space." 2492

LOS ANGELES (AP) — Republican Young Kim has defeated Democratic U.S. Rep. Gil Cisneros in Southern California. The contest was a rematch from 2018, when Cisneros delivered an upset in what had been a longstanding GOP district anchored in Orange County. Kim’s victory Friday in the 39th Congressional District overcame President Donald Trump’s poor performance in heavily Democratic California, where he got only one-third of the votes. The former state lawmaker was born in South Korea and grew up in Guam. Another California Republican born in South Korea — Michelle Steel — defeated Democratic U.S. Rep. Harley Rouda in another Orange County district. 661

LOS ANGELES (AP) — Fresh snow coated the slopes of the Sierra Nevada on Thursday as a late-spring storm with winter-like potency moved through California, forcing rescues and adding to snowpack and rainfall totals that are already well above normal.Authorities rescued four hikers caught in the weather on the far north's Redwood Coast and two people trapped on a tiny island in the suddenly fast-flowing Los Angeles River.Mammoth Mountain, a popular ski area in the Sierra, reported a foot (30 centimeters) of new snow on its peak, boosting the season total at the summit to nearly 58 feet (18 meters). The resort already announced it had enough snow to allow skiing and boarding through the Fourth of July. Mammoth expects up to two feet of snow by Friday morning. Jason Elrick eagerly followed the storm's progress from his desk at a staffing office in Chino, east of Los Angeles. As the snow piled up at Mammoth, he vowed to make the five-hour drive to the resort late Thursday and hit the slopes in the morning."I have a bit of flexibility at work so I can say, 'Boss, it's snowing. I have to go,' " Elrick said. "The conditions are prime. It's like the middle of winter up there."Elrick, 37, said he expects Friday to be a "bluebird day" — skier slang for sunny conditions following a major snow dump.The wettest winter in years nearly eliminated drought conditions in California. While frequently disrupting travel, a long series of storms stoked a big part of the state's water supply — the Sierra snowpack that melts and runs off into reservoirs during spring and summer.More snow was expected, and winter storm warnings would remain in effect until early Friday for the southern Sierra from Yosemite south to Kern County, the weather service said."Looks like a Winter Wonderland in mid-May!" the Sacramento National Weather Service tweet ed, showing traffic camera images of snowy Interstate 80, a major route that crosses the Sierra north of Lake Tahoe.The unusually cold and wet late-season storm not only put a gray, wintry cast on the Golden State, it posed a problem for travelers and outdoor enthusiasts who normally find moderate conditions by late spring.The California Department of Transportation closed State Route 89 over Monitor Pass. Yosemite National Park earlier announced the closure of a popular road because of the storm.Sequoia National Forest officials warned people wondering when campgrounds and access roads will open that snow is deeper than normal, and recreation sites, roads and trails will be wetter than average. Forest crews normally try to open most campgrounds in time for the Memorial Day weekend, the forest said.The storm unleashed rain in Northern California on Wednesday. Some San Francisco Bay Area cities received around an inch (2.5 centimeters), and an area to the north in Sonoma County that's typically very wet got more than 5 inches (12.7 centimeters).Before dawn, Humboldt County sheriff's deputies found four hikers who had trekked from their vehicles several miles to camp at Gold Bluffs Beach. The storm blew away their tent, and they took shelter in a restroom facility.The rain spread south and reached Southern California in time to make the Thursday morning commute slippery and adding to seasonal rainfall that's already above normal.Alicia Ochoa said she briefly considered staying home from her job as a street vendor in Santa Ana. Instead she bundled up with a sweater, jacket and hat and ventured out in the rain."The water isn't going to stop me," Ochoa, 74, said in Spanish while setting up sodas for sale. "We've got to work."The storm turned the normally languid Los Angeles River into a torrent, trapping two people on a small island of vegetation northeast of downtown. A Fire Department swift-water rescue team managed to reach them by boat.Snowfall in Southern California mountains could reach elevations as low as 6,000 feet (1,829 meters) Thursday night, the San Diego weather office said.Forecasters predicted more rain during the weekend and into early next week. 4052

LOS ANGELES (AP) — Several Republican candidates gained ground in updated vote counts in closely fought House districts in Southern California. In the 50th District anchored in San Diego County, Republican former Rep. Darrell Issa padded his lead to more than 16,000 votes. The district was previously held by Republican Duncan Hunter, who resigned after pleading guilty to conspiracy to misuse campaign funds for personal use.As of Friday afternoon, Issa led Democratic challenger Ammar Campa-Najjar 146,398 to 130,226 votes, with 66% of precincts reporting.Republicans are trying to recapture some of the seven districts the party lost to Democrats in 2018.Republican Rep. Mike Garcia in the 25th District north of Los Angeles was trailing Democrat Christy Smith but Thursday's vote count update gave him a slight edge. In the 48th District in Orange County, Republican Michelle Steel added about 2,000 votes to her lead over Democratic Rep. Harley Rouda. 966