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SAN DIEGO (KGTV) - After moving to San Diego almost three years ago, Derek and Terri Ruff are on a mission to experience everything the city has to offer. “Yes we are, it’s fantastic! We hardly leave the county, there’s just so much to do," said Derek.The couple moved here from New Mexico, and for nine years Derek's colon cancer seemed to be behind them. “I won’t say cancer-free, but I didn’t have any symptoms for years, until last May, whenever I came in for a checkup, and they discovered cancer again," said Derek.It was stage IV metastatic colon cancer.“It’s a lot. It’s a tough diagnosis, it’s really difficult to live through.”After three months of aggressive chemotherapy, Ruff's condition only got worse. His journey brought him to UC San Diego Health's Moores Cancer for a clinical trial, which unfortunately did not work. But he Ruff became a candidate for another trial involving natural killer cells created from stem cells.“These are patients who don’t have a lot of good options in terms of chemotherapy or immunotherapy," said Dr. Sandip Patel, a medical oncologist who is leading the trial at UCSD. Decades of research on natural killer cells have culminated in the new cancer treatment being developed by San Diego-based Fate Therapeutics.Fate is the first to mass produce cancer-killing cells from a type of stem cell called a human-induced pluripotent stem cell (iPSC). "The concept of utilizing the stem cells that are within us, within our blood factory, within our blood marrow, to create a master bank of cells that we can utilize to program in different ways to fight cancer with cellular immunotherapy."The off-the-shelf, iPSC-derived natural killer cell cancer immunotherapy received U.S. Food and Drug Administration approval to move into clinical trials in November 2018. Ruff is the first person in the world to receive the treatment and got his first dose in February.“Being the first is exciting but it was less so hearing that you have stage iv cancer and you don’t have much of a future, and now I feel hopeful, again," said Ruff.While it's too early to tell if the treatment is working, researchers are hopeful this treatment will one day help many cancer patients. 2212

SAN DIEGO (KGTV) -- A shortage of labor is creating big problems for San Diego farmers. According to the San Diego Farm Bureau, the slowing workforce is expected to impact local farmers and the price we pay at the grocery store. The bureau says the problem stems from an aging work force, the lack of an easy-to-navigate visa program, and the cost of living in San Diego County. There is a visa program available, but for San Diego’s smaller farmers, the process is complicated and expensive. Created in 1986, the H-2A visa was designed to help understaffed farmers hire foreign workers. The problem? The visa program requires farmers to pay its H-2A employees a set minimum wage, .92 per-hour in California. Farmers are also required to provide housing, food and transportation to H-2A workers. California isn’t alone, other states like Idaho are also struggling to find help.According to an Idaho newspaper – The Post Register, a recent migrant shortage and costs associated with the program are forcing some farms out of business. Although times are tough for farmers in San Diego, the bureau says there is a solution – creating a boiled down visa program that simplifies things for farmers and the workers they need. Friday morning on 10News at 6, Kalyna Astrinos takes a deeper look at the impact on San Diego farmers and the decisions they face in the midst of the shortage. 1392

SAN DIEGO (KGTV) - Across the county, doorbell camera video has caught 'grinches' behaving badly."Upsetting and makes me feel violated," said Catherine Butler, who lives on Palm Avenue in La Mesa.When Butler woke up Wednesday morning, she came upon a mess outside her home. A wreath hanging on the side of her home was on the ground. A lighted garland was cut and left in her yard. She found a string of cut-up Christmas lights near the sidewalk.RELATED: How to stop porch pirates from stealing your packages around the holidays"It makes me mad. It's not right and it's very grinchy," said Butler.Surveillance video reveals the culprit: a man walking barefoot on her patio railing, yanking down her lights. "I put up things because it's fun to be in the season. To have something negative happen, it just feels really personal," said Butler. Butler is hardly the only one feeling that way. There have been a plethora of videos posted this week of package thieves throughout the county, likely targeting Christmas presents. In Chula Vista, a video posted on the Neighbors App by Ring shows a man wrangling a large holiday wreath off a front door. In the post, the homeowner says the wreath had been put up for the last 15 years.In another post from Spring Valley, a person seen walking away from a home and into a waiting car took a Mickey Mouse projector light. Sometimes, a grinch can be dangerous. RELATED: A porch pirate stole a package from a home, then threw shade with a snarky 'thank you' note In Escondido, the Pimentel family recently told 10news their six, holiday inflatables were the likely target for vandals on Saturday night, after they found BBs wedged in their home. Part of their living window was shattered, as their children were inside watching 'The Polar Express."Ring videos show several grinches in a neighborhood in Del Sur, but these thieves had a change of heart. Teens are seen nabbing a 0 projector light. The victim posted the video on social media Wednesday and hours later, a teen was recorded dropping it off on the front doorstep. 2075

SAN DIEGO (KGTV) -- America’s Finest City ranked high on a new list of best cities for jobs in 2019, according to WalletHub. San Diego ranked 28th out of 182 cities overall. Chula Vista also made the list, coming in 123rd place. According to the report, the national unemployment rate has fallen to an 18-year low of just 3.7 percent, while hiring also is up. College graduates are also beginning to see the benefits of the strong job market. According to the National Association of Colleges and Employers, employers plan to hire 16.6 percent more members from the class of 2019 compared to the previous year. Though San Diego secured a strong spot on the list, many cities ranked higher. See the top five cities for jobs in 2019 below: Scottsdale, AZColumbia, MDOrlando, FLSan Francisco, CAColorado Springs, CO 821

SAN DIEGO (KGTV) – All orphaned dogs and nearly all cats at the Helen Woodward Animal Center found a home for the holidays, the center announced Thursday. A total of 64 dogs and 35 cats were adopted between December 17 and 23. The “Home 4 the Holidays” campaign started in 1999 in an effort to encourage winter-season pet seekers to choose adoption. Empty kennels give the center the opportunity to save more animals. A new group of orphaned dogs and cats are being transported to the center and will arrive before January. “This is like a little Christmas miracle,” explained Center Operations Director Jennifer Shorey. “We are delighted to help extend this bit of magic into the New Year.” 699

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