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BEIJING, Sep. 13 (Xinhuanet) --Experts have called for a national drug-control system after a nationwide deficit of a life-saving drug, which has lasted at least three months.Doctors at a Beijing hospital said some specialized hospitals, which perform hundreds of cardiac operations every month, have been paralyzed by their lack of protamine sulfate, which is commonly administered after heart surgery to reverse the anticoagulant effects of heparin.The earliest report of a shortage was in Hubei province on July 21. This was followed by reports of shortages in Guangdong, Shandong and Liaoning provinces.The Shandong newspaper, Qilu Evening News, quoted a regional sales manager, surnamed Zhuang, as saying the province had been allocated 150 doses of protamine sulfate after Shanghai No 1 Biochemical and Pharmaceutical Co Ltd recently resumed production of the drug."But its monthly use here is usually 10,000 doses," he said.The Ministry of Health has denied it is responsible for supplies of the drug and passed the buck to the State Food and Drug Administration, claiming the latter is responsible for the supervision of medicines.Shen Chen, head of the publicity office of the State Food and Drug Administration, said he was unaware of the shortage, but said the administration is responsible for the quality of medicines, not the supply."Development and reform authorities oversee the medicines' prices, while the industrial and commercial authorities oversee the storage. The food and drug departments only cover the approval and quality of medicines."Industry insiders said one of the reasons for the shortage was the low profit margin, which discourages companies from mass producing the drug."Some companies can't earn enough to recover their costs, therefore it is almost impossible to maintain their enthusiasm for continuing production," said Lu Guoping, secretary-general of the Shanghai Pharmaceutical Trade Association.Lu said the government should issue policies to prevent future shortages of such medicines to avoid possible nationwide public health incidents.Yi Shenghua, a lawyer at Beijing Yingke Law Firm, said the country should have a unified system to guarantee the normal supply of medicines that are widely used and drug manufacturers should fulfill their responsibilities to society, even though there is no law stipulating they should produce specific medicines.He came up with two ways to deal with the problem of companies only producing profitable drugs."The government can order businesses to manufacture a certain amount of cheap medicines. Or it can offer financial assistance to subsidize cheap, but life-saving medicines."

BERLIN, June 17 (Xinhua) -- German authority said on Friday first case of human spreading deadly E. coli is detected, as death toll increases to 39 worldwide.A woman working in a kitchen of a catering company was infected by E. coli from sprouts, though she didn't fall ill immediately, said Harald Kehlborn, a spokesman for the consumer protection ministry of German state Hesse.Then she spread E. coli unconsciously to another 20 people through the food she prepared, said Kehlborn.The woman later developed serious complication of hemolytic- uremic syndrome (HUS), which causes failure of kidney and nervous system.According to the data of the Robert Koch Institute, Germany's national disease control centre, the number of people who are infected has reached 3,408 in Germany and 798 people have fallen into HUS, while the infection speed is slowing down.

SAN FRANCISCO, July 14 (Xinhua) -- Microsoft on Thursday introduces a hacking alert system to its Windows Live Hotmail email service alongside banning common passwords."When someone's account gets hijacked, their friends often find out before they do, because the hijacker uses their account to send spam or phishing email to all their contacts," said Microsoft in a blog post.The new security feature adds a "My friend's been hacked!" option in the "mark as" menu in Hotmail and also enables users to report hacked accounts via the junk mail filing screen.Then an alert will be sent to Microsoft, which will "make sure the account can no longer be used by spammers and activates an account recovery process to allow the owner to take back control the accounts."Users can report any email account as compromised and Hotmail will provide the information to other email providers like Yahoo! and Gmail, said the blog.Meanwhile, Microsoft said Hotmail will roll out a feature to prevent users from choosing commonly used and weak passwords, such as "123456," "ilovecats" and "gogiants." Users who currently use a weak password will be asked to change to a stronger one in the future.Hotmail, first launched in July 1996, is one of the first free email providers, and was acquired by Microsoft in 1997 for an estimated 400 million U.S. dollars.According to statistics released by comScore last August, Hotmail was then the world's largest web-based email service with around 364 million users, followed by Yahoo! Mail (280 million) and Gmail (191 million).

MOSCOW, Aug. 30 (Xinhua) -- Russia's space agency said Tuesday that a Proton-M rocket launch failed earlier this month because of a malfunction in the upper stage.The conclusion was reached by an independent investigation commission following a series of checks, Roscosmos said in a report that was posted on its website."The commission reported that the time span reserved for the gyrostabilized platform's turn was miscalculated and narrowed, which caused the Briz-M upper stage's disorientation and the satellite's journey to a wrong orbit," the agency said.Other systems in the upper stage performed well, the agency said, adding it has lifted a ban on launches of the Proton-M carrier rockets equipped with the Briz-M upper stage.Local media reported the Briz-M, manufactured by the Khrunichev State Research and Production Space Center, has had five failures over its 12-year history of operation.On Aug. 18, a Proton-M carrier rocket failed to deliver a communications satellite into orbit. After the failure, Russia suspended launches of Proton-M rockets pending the outcome of an investigation into the failure.

HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.