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SAN FRANCISCO, Nov. 12 (Xinhua) -- Apple has unveiled a worldwide replacement program for the first-generation iPod nano music player due to overheating battery issues, telling owners to stop using the product and get it replaced for free."Apple has determined that, in very rare cases, the battery in the iPod nano (1st generation) may overheat and pose a safety risk. Affected iPod nanos were sold between September 2005 and December 2006," said Apple in a notice posted late Friday on the support section of its official website.The company said the issue has been traced to a single battery supplier that produced batteries with a manufacturing defect. Since the product is five or six years old now, the likelihood of an incident increases.Owners of iPod nano can check the serial number on the back of the product to see if it is eligible for replacement. Apple promises a replacement unit about six weeks after the company received the affected one.The overheating battery issues of the first generation iPod nano have been known for years. In 2008, Japan's Ministry of Economy, Trade and Industry launched an investigation into Apple after dozens of iPod overheating cases were reported, including several incidents of iPod nanos toasting to the point of catching fire and causing minor burns to owners.Last August, a commuter train in Tokyo was delayed during rush hour when passengers complained of a strong burning smell from an overheating iPod nano that had burst apart.The portable music player also cost Apple a 22.5 million-U.S. dollar settlement in 2009 when a class action lawsuit in California alleged iPod nano is prone to scratches and its alleged defects were not disclosed by the company.

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

ACCRA, Dec. 19 (Xinhua) -- A strange disease has hit inhabitants of the Amansie West District in the Ashanti Region of Ghana, near Kumasi, 270 km north of the capital, claiming two lives, health officials said here on Monday.Director of Public Health Dr. Joseph Amankwa told Xinhua that the disease, which had been identified as Laffa viral hemorrhagic fever, and had symptoms similar to those of malaria, caused victims to bleed to death.Dr. Amankwa said he received information about the infection over the weekend but indicated that no other details were made available."We are sending a team to the affected area to verify what the actual situation is to determine our next action. We are also liaising with the World Health Organization to gather enough data on the infections and soon information will be sent out to the public," he said.According to reports carried by local Joy fm radio station, the disease was the first of its kind in the country.The reports quoted health officials as saying infection was passed on from infected rodents like mice and rats and was highly contagious."About two months ago, a young man of 19 years came to our health center here and complained of malaria, so we treated him for malaria but suddenly, blood started coming from the nose, mouth, anus and the ears, and immediately he died," Municipal Director of Health in the Amansie West District, Dominic Brobbey told the radio station.He warned that although the situation was under control, there were no drugs to treat the disease in Ghana, and therefore urged government to expedite action to acquire the necessary drugs to prevent further deaths.

BEIJING, Jan. 20 (Xinhuanet) --The air quality has worsened in the Chinese capital since Wednesday, triggering renewed discontent among residents.Without rainfall and wind to dispel pollutants, particulate matter has been accumulating in the air. Most monitoring stations measured PM 10 (particulate matter smaller than 10 micrograms) at higher than 300 micrograms a cubic meter.In southwestern Beijing's Fangshan district, the Liangxiang station recorded 516 micrograms of PM 10 a cubic meter, the highest reading of the day, according to the Beijing Municipal Environmental Monitoring Center.More than 150 micrograms a cubic meter is considered hazardous to health.Beijing has been shrouded by heavy smog off and on this winter, and the ongoing air concerns are wearing on residents particularly as they prepare to celebrate the Spring Festival holiday next week."I almost got choked by the smog when I stepped out of the office building on Wednesday," said Yang Yanli, 24, an accountant. "The smell is so terrible, as though I'm inhaling chunks of coal, that it has spoiled my holiday mood.""PM 10 intensity has been particularly high these days," said Wang Qiuxia, a researcher at the Green Beagle, a non-governmental organization based in Beijing.Unlike the smog that hit mostly the southern part of the capital on Jan 1, the smog in recent days has shrouded the entire city, according to the Beijing environmental protection bureau.Worse yet, it will linger until Saturday, when the wind will pick up and disperse it, the bureau predicted.The Chinese Center for Disease Control and Prevention suggests people stay at home to protect themselves from respiratory and heart problems triggered by heavy smog."The intensity of indoor pollutants is 30 to 60 percent lower than those outdoors during a hazy day," said Xu Dongqun, an officer with the environmental bureau. "I suggest people with respiratory problems put off traveling if the smog lingers."But many people said they had to brave the foul air to travel, especially migrants who are eager to reunite with their families during Spring Festival."No one likes to travel when the air is this bad, but do you have any choice when Spring Festival is coming?" asked Feng Xiao, a public servant at China's General Administration of Sport. The 24-year-old plans to travel by train from Beijing to her hometown in East China's Shandong province on Friday.

BRATISLAVA, Dec. 22 (Xinhua) -- The Slovak Education Ministry on Thursday launched an internet website to provide the general public with digitalized textbooks.According to Education Minister Eugen Jurzyca, the public could access a total of 26 digitalised textbooks, compulsory-reading books and download 65 audio-recordings on the website of eaktovka.sk.The word aktovka means schoolbag in Slovak."We hope that pupils will be able to study even in places where they don't bring their textbooks, such as during the holidays at their grandma's, but also that teachers will have an easier time putting together various textbooks or their sections on, for example, physics or chemistry," said the minister.Jurzyca said he estimated that 92 percent of households with school-age children which own personal computers and 70 percent of those which have access to the internet would visit the website.