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SAN DIEGO (KGTV) -- You've got the chance to start the new year right, with free Miranda Lambert tickets! Interested? Here's how you win:WATCH: 10NEWSWHEN: Wednesday, November 8 at 11 p.m., after the Country Music Awards on ABC.HOW: Watch to win. A cue to call will pop up on your screen, giving you the number you need to call for your chance at the tickets.See you at 11 p.m., San Diego!*The CMAs start tonight at 8 p.m. 431

SAN DIEGO (KGTV) -- Two of San Diego County’s largest cities are among the happiest in the nation, according to WalletHub. San Diego ranked 32nd on the list of 182 cities followed by Chula Vista, which ranked 35th on the list.San Diego ranked 14th on the list for emotional and physical well-being while taking the 28th spot for income and employment.Meanwhile, Chula Vista ranked 82nd in the physical and emotional well-being category and 9th for income and employment.Check the list below for the top five happiest cities in the U.S. 543

SAN DIEGO (KGTV) - Two men wearing masks and gloves robbed a City Heights jewelry store Friday.One of the men jumped a display counter and confronted an employee of the Eclipse Jewelry Store at 4213 University Ave. just east of Interstate 15, police said.One man took jewelry from display trays and put it in a bag while the second man pointed a gun at the employee.The owner told 10News the men got away with about ,000 worth of mostly gold chains. He also said he thought perhaps the men had been in the store before since they seemed to know exactly what they wanted. Both men ran off and were last seen getting into a silver colored late model Toyota or Honda heading east.No one was injured in the robbery. Police did not have detailed descriptions of the suspects. 791

SAN DIEGO (KGTV) — While Saturday will start off cold, temperatures will improve through next week throughout San Diego County after a week of chilly temps and weather.A Frost Advisory will be in effect through 9 a.m. Saturday for the Inland Empire and San Diego County's valleys, as temperatures dip to the 30s an 40s, according to the National Weather Service. At higher elevations, temps could hit the teens.While temperatures are expected to warm up, conditions through the weekend will keep road conditions through some mountain roads dangerous. Snow and ice that had built up through the week will still be present, with a slight chance of flurries for the mountains Saturday.WEATHER: Up-to-date conditions throughout San Diego CountyWith the cold weather Saturday, black ice in some areas could be present. Chain restrictions or road closures may still be required.But warmer weather is on the horizon. Temperatures are expected the return to normal for this time of the year by the middle of next week, according to NWS. 1036

SAN DIEGO (KGTV) -- We’ve known for a while that COVID-19 hits people over 65 especially hard, but a study published Wednesday from researchers in San Diego offers new insight into why that happens.The numbers are staggering: if you’re 65 or older, your risk of winding up in the hospital from COVID-19 is five to 11 times higher than someone under 30. Your risk of death is at least 90 times higher, according to data from the Centers for Disease Control and Prevention.Researchers at the La Jolla Institute for Immunology say the reason why older people fare so much worse appears to be from a lack of T-cells, a type of white blood cell that can decline with age.“Some viruses get controlled by one part of the immune system. Some viruses get controlled by another. In this case it seems that T-cells really do a lot of the work,” said Dr. Shane Crotty, one of the authors of the study published Wednesday in the journal Cell.Dr. Crotty and his colleagues looked at 50 people infected with the virus, and they measured the three elements of the adaptive immune system in detail: antibodies, helper T-cells and killer T-cells.Then they compared the measurements to how people fared against the virus. Some patients in the study group had severe cases, others had mild infections.The researchers found that people with all three branches of the adaptive immune system tended to fully recover. People with severe cases of the virus often lacked one or more of the immune branches, and it was particularly evident in older people.“Our data indicated that of the older individuals, it was particularly the ones that had fewer T-cells to start that look like they really struggled to control this virus,” Dr. Crotty said.As we age, we have fewer T-cells to send after invading pathogens. “That collection of T-cells gets smaller. So it’s harder to recognize a new virus,” Crotty said.Among the 748 deaths in San Diego County reported as of Wednesday, 87% were people aged 60 and older.The findings from LJI may have implications in the search for a vaccine against COVID-19. The data suggests that vaccine-makers may want to target a drug that elicits all three branches of the immune response, Dr. Crotty said. Some vaccine approaches, such as inactivated virus vaccines, only elicit two of three branches, not killer T-cells. However, Crotty said it was too soon to rule any candidates. Two strong branches produced by a vaccine could potentially cover for the lack of a third, he said.Crotty said the findings could help vaccine-makers interpret results from the clinical trials and find the right dosing.“Is a given vaccine a good vaccine, and you just need a booster immunization?” he said. “Does it work well in one population but it doesn’t help in the elderly because it doesn’t generate a T-cell response, for example? Those are the scenarios when this type of knowledge will come into play.” 2906