宜宾自体软骨隆鼻术费用(宜宾韩式双眼皮哪好) (今日更新中)

With heavy hearts, we can confirm that Prayer Warrior was humanely euthanized following an injury in today’s sixth race on the main track.Our deepest sympathies to the Metz family and their team.— Del Mar Racetrack (@DelMarRacing) November 11, 2019 262

With its low air pressure, Hurricane Michael unofficially sits as the third-strongest landfalling hurricane to strike the United States. Having such a tremendously low air pressure typically causes storms to have strong winds, and Michael was no exception. Hurricane Hunters from the Air Force and NOAA estimated Michael's lowest pressure was 919 MB at landfall. The only two hurricanes with a lower pressure at landfall to hit the United States were the Labor Day Hurricane of 1935 and Camille of 1969.Also based on estimates, Michael had top winds of 155 MPH, which is just below Category 5 status. Based on top winds speeds, Michael was tied for the sixth-strongest landfalling hurricane in US history, tied with Hurricane Maria in 2017 and "Guam" in 1900. In terms of air pressure, Michael was 1 MB stronger than Katrina in 2005 and Maria in 2017 at landfall, and 3 MBs stronger than Andrew of 1992. Michael's top winds at landfall were well ahead of Katrina's top winds at landfall of 130 MPH, on par with Maria's top winds at landfall of 155 MPH, but below Andrew's top winds of 165 MPH.But in the immediate aftermath of Andrew, it was declared a Category 4 hurricane at landfall. It was not until years later when the National Hurricane Center concluded that winds in Andrew were greater than 157 MPH, marking the only Category 5 hurricane to strike the US since Camille in 1969. Like Andrew, Michael continued to strengthen all the way until landfall. In just three days, the storm went from a tropical storm to a high-end Category 4 hurricane. Other reasons Micheal will be notable:- Michael was just the sixth hurricane of at least Category 4 strength to hit Florida since 1950.  1752

With a coronavirus vaccine still months off, companies are rushing to test what may be the next best thing: drugs that deliver antibodies to fight the virus right away, without having to train the immune system to make them.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. Vaccines work by tricking the body into thinking there’s an infection so it makes antibodies and remembers how to do that if the real bug turns up.But it can take a month or two after vaccination or infection for the most effective antibodies to form. The experimental drugs shortcut that process by giving concentrated versions of specific ones that worked best against the coronavirus in lab and animal tests.“A vaccine takes time to work, to force the development of antibodies. But when you give an antibody, you get immediate protection,” said University of North Carolina virologist Dr. Myron Cohen. “If we can generate them in large concentrations, in big vats in an antibody factory ... we can kind of bypass the immune system.”These drugs are believed to last for a month or more and could give quick, temporary immunity to people at high risk of infection, such as health workers and housemates of someone with COVID-19. If they proved effective and if a vaccine doesn’t materialize or protect as hoped, the drugs might eventually be considered for wider use, perhaps for teachers or other groups.They’re also being tested as treatments, to help the immune system and prevent severe symptoms or death.“The hope there is to target people who are in the first week of their illness and that we can treat them with the antibody and prevent them from getting sick,” said Dr. Marshall Lyon, an infectious disease specialist helping to test one such drug at Emory University in Atlanta.Having such a tool “would be a really momentous thing in our fight against COVID,” Cohen said.Vaccines are seen as a key to controlling the virus, which has been confirmed to have infected more than 20 million people worldwide and killed more than 738,000. Several companies are racing to develop vaccines, but the results of the large final tests needed to evaluate them are months away.The antibody drugs are “very promising” and, in contrast, could be available “fairly soon,” said Dr. Janet Woodcock, a U.S. Food and Drug Administration official who is leading government efforts to speed COVID-19 therapies. Key studies are underway and some answers should come by early fall.One company, Eli Lilly, has already started manufacturing its antibody drug, betting that studies now underway will give positive results.“Our goal is to get something out as soon as possible” and to have hundreds of thousands of doses ready by fall, said Lilly’s chief scientific officer, Dr. Daniel Skovronsky.Another company that developed an antibody drug cocktail against Ebola — Regeneron Pharmaceuticals Inc. — now is testing one for coronavirus.“The success with our Ebola program gives us some confidence that we can potentially do this again,” said Christos Kyratsous, a Regeneron microbiologist who helped lead that work.Regeneron’s drug uses two antibodies to enhance chances the drug will work even if the virus evolves to evade action by one.Lilly is testing two different, single-antibody drugs — one with the Canadian company AbCellera and another with a Chinese company, Junshi Biosciences. In July, Junshi said no safety concerns emerged in 40 healthy people who tried it and that larger studies were getting underway.Others working on antibody drugs include Amgen and Adaptive Biotechnologies. The Singapore biotech company Tychan Pte Ltd. also is testing an antibody drug and has similar products in development for Zika virus and yellow fever.“I’m cautiously optimistic” about the drugs, said the nation’s top infectious diseases expert, Dr. Anthony Fauci. “I’m heartened by the experience that we had with Ebola,” where the drugs proved effective.What could go wrong?— The antibodies may not reach all of the places in the body where they need to act, such as deep in the lungs. All the antibody drugs are given through an IV and must make their way through the bloodstream to wherever they’re needed.— The virus might mutate to avoid the antibody — the reason Regeneron is testing a two-antibody combo that binds to the virus in different places to help prevent its escape.Skovronsky said Lilly stuck with one antibody because manufacturing capacity would essentially be cut in half to make two, and “you will have less doses available.” If a single antibody works, “we can treat twice as many people,” he said.— The antibodies might not last long enough. If they fade within a month, it’s still OK for treatment since COVID-19 illness usually resolves in that time. But for prevention, it may not be practical to give infusions more often than every month or two.A San Francisco company, Vir Biotechnology Inc., says it has engineered antibodies to last longer than they usually do to avoid this problem. GlaxoSmithKline has invested 0 million in Vir to test them.Giving a higher dose also may help. If half of antibodies disappear after a month, “if you give twice as much, you will have two months’ protection,” Lilly’s Skovronsky said.— The big fear: Antibodies may do the opposite of what’s hoped and actually enhance the virus’s ability to get into cells or stimulate the immune system in a way that makes people sicker. It’s a theoretical concern that hasn’t been seen in testing so far, but large, definitive experiments are needed to prove safety.“As best as we can tell, the antibodies are helpful,” Lyon said.___Marilynn Marchione can be followed on Twitter: @MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 5919

When we first met Mark Lee Jr. in 2018, he had been working with the group Justice for TEDD Handlers to try and reunite with his K-9 partner Rayco. The two were part of the Army’s bomb detection team.Lee was injured in Afghanistan and left in 2012. It was the last time he saw Rayco.Also in 2018, a report came out that said the Army mismanaged the adoption of more than 200 military dogs, leaving veterans like Lee without the chance to adopt.When Rayco finished his service with the military, he ended up working with the U.S. Capital Police (USCP).The Justice for TEDD group, made up of a few civilians like Betsy Hamptom, were fighting to try and locate these dogs to reunite them.Meanwhile, Lee was struggling. He ended up behind bars and in rehab.“I didn't do too well,” said Lee. “I guess everything kind of caught up with me. While I was incarcerated. The guy at Capitol police that had Rayco watched our initial interview.”After our story, USCP technician Stephen Nunn got in touch with Justice for TEDD Handlers and said he wanted Rayco back with Lee.“It’s been 180 degrees since then, as you can see, I got my best friend back,” said Lee. “It shows a lot about his character being that when he reached out to find me as a law enforcement officer and find out I was incarcerated and still do nothing but want me to have him back.”Lee reunited with Rayco in D.C. and then the two went to Indiana to thank the woman who made it possible.“This is the one I wanted to happen for so long,” said Hampton. “This is a big deal to me. He’s like a son to me. My husband and I have adopted this kid.”It’s like the two old war buddies haven’t missed a beat.“He still has his working harness so if I pull it out of my backpack or pull it up, he goes crazy because he thinks he’s going to get to go work and have some fun,” said Lee.The pair isn’t finished yet either. They are moving to Texas to work with Mission K-9 Rescue. They will help rehabilitate dogs with PTSD, so they can find homes and reunite other military handlers.“Me and Rake are going to go over there and see if we can help somebody else get their boy back,” said Lee.The Justice for TEDD Handlers program is winding down. They were able to reunite 12 handlers with their dogs. A few others went to visit their old K-9 partners. Marines had similar issues finding their improvised explosive device detection dogs after service.The report on the mishandling of K-9s did lead to a change within the military to make sure this doesn’t happen again. 2518

With a total of six adopted and foster children, Keri Penland’s family is an exercise in planning and patience.“Trying to do school with them has been insane,” she said.All of her kids are school-aged; some have learning disabilities. When the coronavirus pandemic hit, they--along with tens of millions of other students across the country--became part of a nationwide experiment in remote learning.Her verdict?“I don't know how anybody is doing this, to be honest,” Penland said. “It's not possible.”And it turns out, she's not alone.“We found that remote learning is really failing our most vulnerable learners,” said Justin Ruben, who is with the nonprofit “ParentsTogether.” The group recently conducted a survey of more than 1,500 families across the country to see how remote learning was going.Among the findings:When compared to a family making 0,000 a year, lower-income families--making ,000 or less-- are ten times more likely to have children doing little to no remote learning.Those families are also five times more likely to attend a school not offering distance learning materials at all and 13 percent of them didn’t even have a computer device or internet access.Yet, the numbers were even worse for families of children with special needs, who usually get individualized support at school. Out of those families, 40 percent said that with remote learning, they were receiving no support at all.“A huge chunk of students are being left behind by remote learning,” Ruben said.ParentsTogether wants the federal government to step in with 5 billion more in funding for education, especially since the coronavirus pandemic slashed tax revenues for local and state budgets and, in turn, education programs.“Schools are making budgets right now and kids are falling behind right now, and schools are making plans for the fall right now,” Ruben said. “And so, there's this surreal lack of urgency in Washington, D.C., and there’s literally like a whole generation of vulnerable kids is being allowed to languish.”Back at Penland’s house, it’s been an unusual ending to the school year.“I'll tell you, if school doesn't start again, the kids are gonna be way, way behind,” she said. “It's a different time than we've ever experienced.”Given everything that happened with schools and the pandemic, experts have some suggestions for how to keep kids engaged and learning over the summer.Keep some semblance of structure. A visual schedule that everyone can see will help and make it easier for you and your kids to get back into the swing of things when summer ends.Read to your children or encourage them to read, write or draw--anything that engages their minds, as long as it does not involve a computer or phone screen.Outdoor hikes, walks or scavenger hunts can help kids get exercise and keep them engaged in discovering new things.Make sure your kids get enough sleep and proper nutrition, to keep them in top shape and ready for when it’s time to return to school. 2998

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