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Researchers have found a new way to predict some aspects of mental illness, before it happens. They used artificial intelligence and more than 60 million health records. Dr. Bruce Kinon has always been fascinated by the brain. Motivated by a desire to find better treatments for mental disorders, he co-authored a study in a collaboration with Lundbeck and Kings College in London. They developed a tool that could identify early symptoms of "first episode of psychosis,” commonly referred to as when someone has a "break."“Most schizophrenia begins with the first episode of psychosis. This is a marked change in normal behavior. This is where the patient all of a sudden, rather suddenly, begins acting bizarrely, may have thoughts not based in reality,” Dr. Kinon explained. That first episode is critical, and the beginning of the lifelong disability known as schizophrenia. So, what if they could predict that first break? It's not something you can test for. “What we’ve done in this study is basically developed a population tool that one could screen populations of individuals who haven’t been identified through any health care professional as possibly having those precedence of developing a prodromal or at risk state for psychosis,” Dr. Kinon said.Dr. Kinon says there's usually some sort of stressor that leads to that break.“These periods of first psychosis seem to be preceded by what we call prodromal symptoms, a simmering, under the surface of symptoms,” he said. “Usually the individual feels out of sorts, that they don’t understand what’s going on around them. Their social relationships may be aborted."Dr. Kinon worked with IBM Watson Health Explorys Solutions. They took more than 60 million anonymized health records, including those who'd had a diagnosis of first episode of psychosis, and put them through privatization machines and let the artificial intelligence do the work. “Sometimes when you have all this data across billions of data points across thousands of patients, it becomes hard for us as humans to see the data and find patterns that’s where machine learning comes into play,” said Dr. Anil Jain, Vice President and Chief Health Information Officer at IBM Watson Health.Dr. Jain says think of it like a virtual clinical study, where you're looking for patterns. And imagine how that could one day help doctors. It took two years to get to this point, and they're not done yet. Now that there's a predictive model looking for patterns, they need to design a clinical trial so as to create an intervention. “Imagine down the road, not today, that you put this model back in the hands of clinicians who are taking care of patients that’s how you connect the dots between what we can discover from big data and real world evidence and machine learning algorithms back to the practice of medicine.”There's still a lot of questions. Would people want to know what's coming? Or the risks? Or the stigma? But for now, it's a big step, using big data, possibly leading to big medical breakthroughs. Dr. Kinon has hope for the future, and hope for prevention for those with mental illness. In the meantime, he wants people to reach out to the many organizations, like the 3221

Several feet of snow have fallen and power lines are down in the Rockies -- and it's only September.A winter storm is blowing through parts of the region this weekend, just days after the start of fall.So far, parts of Montana have received almost two feet of snow. Browning was blanketed by 23 inches and East Glacier Park by 21.The National Weather Service's winter-storm warning for portions of north-central Montana is in effect until Monday morning. CNN meteorologist Ivan Cabrera said another one to two feet of snow may fall by then.A 554

SAN MARCOS, Texas — Much of Sean Makra's life has been a fight.But through the struggle, music has always been there. He served 11 years in the U.S. Army, including three year-long tours in Iraq."It's a really ugly side of life that you have to see, and not just the combat side but just with people in general. It brings the worst out," Makra says.Serving in the military led to Makra having substance abuse problems."I got addicted to painkillers, it's a very common story with soldiers," Makra says. "I ended up in jail, and that was the first time in the whole 11 years that I actually was like, 'OK, I can just surrender here.' "Every Monday night in San Marcos, Texas, Makra and fellow veterans meet to use lyrics as ammunition in a battle often fought away from the front lines."It's so intense because every word and every strum of the guitar is releasing, it's purging, and it's beautiful but it's painful," Makra says.Dustin Welch is the musician who founded this group — 994

Science centers, Smithsonian centers, and art museums are shutting down amid the spread of coronavirus. On Thursday evening, the Smithsonian museums, galleries and National Zoo will all close on Saturday indefinitely. The news comes as a hit to the D.C., which was also slated to host the Cherry Blossom Festival later in the month. The Smithsonian issued the following statement:"The health and safety of Smithsonian visitors, staff and volunteers is a top priority. We are closely monitoring the coronavirus situation and maintain ongoing communication with local health officials and the Centers for Disease Controland Prevention. Due to the rapidly changing nature of the situation, we are not announcing a reopening date at this time and will provide updates on a week-to-week basis on our websites. Follow the Smithsonian on Instagram, Facebook and Twitter for immediate updates @smithsonian."The situation is similar in New York, where the Metropolitan Museum of Art is shutting down indefinitely. Here is what The Met had to say:"We will be closing all three locations—The Met Fifth Avenue, The Met Breuer, and The Met Cloisters—temporarily starting tomorrow, March 13, to support New York City’s effort to contain the spread of COVID-19. The Museum will undertake a thorough cleaning and plans to announce next steps early next week. While we don’t have any confirmed cases connected to the Museum, we believe that we must do all that we can to ensure a safe and healthy environment for our community which at this time calls for us to minimize gatherings while maintaining the cleanest environment possible. We look forward to soon announcing when we’ll be able to welcome our staff and visitors back to the Museum.” 1738

So the NBA's inviting 22 teams to Orlando: 13 Western Conference, 9 Eastern Conference. Eight-regular season games per team. Play-in for the 8th seeds. July 31-October 12. Vote tomorrow to ratify. The NBA's back.— Adrian Wojnarowski (@wojespn) June 3, 2020 269

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