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The Food and Drug Administration approved on Wednesday a treatment for the Ebola virus. This is the first FDA-approved treatment for Zaire ebolavirus infection in adults and kids.Zaire ebolavirus is one of four Ebola virus species that can cause potentially deadly infections. It is transmitted through direct contact with blood, tissue or body fluids of an infected person or wild animal.The treatment, Inmazeb, is a mixture of three monoclonal antibodies and was created by Regeneron Pharmaceuticals. The three antibodies work together to bind to the glycoprotein on the surface of the Ebola virus and block it from entry into the body’s cells.Inmazeb was tested in the Democratic Republic of the Congo during an Ebola virus outbreak in 2018-2019 through a partnership between the local government and the National Institutes of Health.A vaccine for Ebola virus was approved by the FDA in December 2019.Regeneron is also the company behind an experimental antibody cocktail that was given to President Donald Trump following his diagnosis of COVID-19, and which he said “cured” him. Trump was also prescribed the antiviral drug remdesivir and the steroid dexamethasone at the time.Regeneron’s COVID-19 treatment is a mix of two powerful antibodies that are believed to boost the immune response to the coronavirus. Early results seem promising, according to initial tests and a press release from the company.The company has submitted an application to the FDA to get emergency approval of their COVID-19 treatment. 1525

The Federal Aviation Administration issued an emergency directive for inspections of certain Boeing 737 planes due to recent reports of engine shutdowns.The FAA issued an emergency airworthiness directive on Thursday for certain Boeing 737s that have been in storage for more than a week.According to the directive, a certain engine valve may be responsible for four recent reports of engine shutdowns. Agency officials suspect that the valve may become corroded during storage, causing it to remain stuck in the open position.The directive requires that any Boeing 737-300, -400, -500, -600, -700, -700C,-800, -900, and -900ER that have been in storage for a week or longer undergo an inspection before being put back into use. The directive also requires inspections for any of those Boeing models that have completed "less than 10 flight cycles" at the time of the directive after coming out of storage.The inspection order was released the same day that CNBC reported that Boeing told lenders to expect fewer deliveries of its 737 Max planes that initially expected. The 737 Max, a plane Boeing has been developing for years, was grounded in 2019 after a series of crashes. 1185

The death of unarmed black men at the hands of police is not an issue often broached in the epicenter of the technology industry.But Ebele Okobi, Facebook's public policy director for Africa, hopes the death of her 36-year-old brother, Chinedu, can begin to change attitudes in the clubby and largely white world of Silicon Valley.The Morehouse College graduate died earlier this month after being tased during a confrontation with sheriff's deputies near San Francisco."It doesn't matter what school you went to," said Ebele Okobi, 44. "You can go to Harvard. You can work in tech. Every black American will tell you they live in a state of constant anxiety. Every black man will tell you they can work at Google, they can be a senior person at Facebook or Apple but when you're driving and you're a black man, you recognize the danger that you're in."The circumstances surrounding Okobi's death on the afternoon of October 3 remain unclear.The San Mateo County Sheriff's Office said deputies encountered Okobi "running in and out of traffic" on a street in Millbrae, a city about 30 miles northwest of Silicon Valley.Okobi "immediately assaulted" a deputy who got out of his vehicle, the statement said. There was a struggle with other deputies who responded.Okobi was taken into custody and transported to a hospital, where he died. A deputy was treated for injuries at a hospital, the sheriff's office said.Tasers were discharged at Okobi three to four times, according to San Mateo County District Attorney Stephen Wagstaff.One or more deputies fired Tasers. It's unclear how many times Okobi was struck, he said.An autopsy has been completed but investigators were awaiting toxicology reports, which could take four to six weeks, Wagstaff said.The district attorney's office, which investigates officer involved deaths, was still interviewing witnesses and combing through surveillance footage in the area, according to Wagstaff."We have hit a period of great concern regarding Tasers," said Wagstaff, adding that Okobi's death was the county's third since December during law enforcement encounters that involved the high-voltage stun guns.Wagstaff said it's still unclear if the Taser contributed to Okobi's death.The district attorney said his office will release video of the incident by mid-December.Ebele Okobi, whose family has retained an attorney, said prosecutors told her there was drone video of the encounter. She said the family's first contact with authorities was Wednesday.Prosecutors would not tell the family whether her brother can be seen assaulting a deputy in the video, she said.The sheriff's office said four deputies and a sergeant were involved in the incident. Deputies in "critical incidents where a death occurs are routinely placed on paid administrative leave, pending investigation," the office said."When the district attorney's office completes an investigation of sheriff's office staff, the San Mateo County Sheriff's Office will often conduct a separate administrative investigation in regards to compliance with our policies," the statement said.Chinedu Okobi graduated in 2003 with a degree in business administration from Morehouse College in Atlanta.He grew up in the San Francisco area as the youngest son of a Nigerian-American family, Ebele Okobi said.Chinedu Okobi, who has a 12-year-old daughter, spent the last decade struggling with mental health issues and may have stopped taking medications earlier this year, according to his sister."He was really gentle," Ebele Okobi recalled. "He was someone people connected to all his life. He was a kind person. He loved poetry. He recorded poetry. He recorded rap. He was also very spiritual and deeply religious."She marveled at the support from executives and others at Facebook."There definitely something insular about tech and definitely something insular about Silicon Valley," she said."But my colleagues at Facebook basically organized themselves and just kept telling the story and saying, this is important. Facebook's mission and Facebook's power to do good in the world -- that's the reason I work there. I've never seen this kind of solidarity and this kind of care."Ebele Okobi said that as a black woman she long feared losing a loved one in a violent police encounter.In 2014, after the birth of her son, she moved her family to London."I think it takes a huge amount of emotional courage to raise black children here and I knew that I didn't have it," she said. "I don't have the emotional fortitude to have a black husband and a black son in America. It's not as if I could take everyone I love with me."She said she hopes her brother's death resonates in Silicon Valley's corridors of influence and privilege."People who never thought this could happen to anybody they know, now know that it can," Ebele Okobi said."I hope this becomes a catalyst for more informed conversations" about police encounters with unarmed black men and the mentally ill as well as the use of Tasers on suspects. "My hope is that now that more people are proximate to these problems that they do something about them."A memorial fund to make donations to the Equal Justice Initiative?was set up in Chinedu Okobi's name. 5227

The coronavirus pandemic has already caused depleted toilet paper shelves and concerns about meat shortages, but now it’s also to blame for some other, maybe more surprising shortages across the country.Coca-Cola announced at the beginning of July that it was stopping production on Odwalla Juice at the end of the month. On a call with investors, James Quincey, Chairman & Chief Executive Officer of The Coca-Cola Co. said of Odwalla, “In the case of a brand like Odwalla and its chilled direct store delivery, which has struggled over the last several years, we started to stop operations effective July 31. This gives us the flexibility to support our investments in brands like Minute Maid and Simply.”And if you thought you were imagining fewer types of Coke products on store shelves, there’s a good chance you weren’t. A representative from the soft drink giant said in an email, “We continue to see high demand for products consumed at home. We are implementing contingency plans as best we can to get the products people want to store shelves. We appreciate everyone’s patience as we work through these unprecedented times,” going on to say, “we are focusing on the availability of our most popular brands.”“Coke is facing is a different sort of thing right now; it's something that's a shift in demand, which is temporary, and they're not in position to respond to it other than to…put all of their eggs into the baskets that are going out the door fastest,” said William Dickens, University Distinguished Professor and chair of the economics department at Northeastern University.Another issue for Coke likely ties into another shortage – aluminum cans.According to Robert Budway, the president of the Can Manufacturers Institute, the aluminium can industry was seeing demand increase even before the pandemic began because cans are more environmentally friendly than plastic bottles, and the demand has only gone up.“Can manufacturers are fully focused on filling the extraordinary demand from all sectors of the industry’s customer base,” said Budway in a statement. He also said that although there is enough aluminum, can makers have announced the construction of several new plants in the United States and Canada, but they will take between 12 and 18 months to build.Chains like Taco Bell announced they’re trimming the menu too, removing things like the 7-Layer Burrito and Nachos Supreme. And Red Robin Gourmet Burgers ditched a third of its menu.The national burger chain cut 55 items, and a representative pointed to what they told their investors about the changes saying the cuts have resulted in “faster cook times, higher quality food” and say it’s reduced waste.“Sure,” said Dickens. “But why wouldn't they have done it before this, if it made such a big difference? The best explanation is that now they're in a different circumstance, and they just can't afford to produce the type of variety that they did before because they aren't having as many people coming in.”Dickens said everything, each menu item and each flavor of soda, has a specific cost to make. For a business to be profitable, it has to sell a certain number of each offering.So it makes sense that less popular items might hit the road right now.“As for menus and shortages…I think we may very well see more firms follow suit. I know my favorite restaurant is only offering a couple of items compared to what it used to. So I know it's a phenomenon that's out there,” said Dickens. “It's more profitable for [restaurants] to focus on a couple of items that they know that they're going to sell a lot of.”He went on to say what we can expect to see in the next month or year largely depends on how things go with COVID-19 and the subsequent handling of the economy.“I guess my biggest fear is that we're mishandling the economy,” said Dickens.He said that the United States’ economy hasn’t shrunk as much as it might have since the pandemic hit because Congress authorized an extra 0 per week for unemployment benefits. He said that the people who are getting those benefits are also then spending that money on things like food and drink.With the final unemployment supplements already distributed, Dickens predicts people will have less money to spend, which in turn will mean less money in the economy overall, more job layoffs – and a deeper recession. He said that could ultimately mean more shortages – and more businesses closing for good.“We should not let the smart things that were done fade away too early, and this is clearly too early since a large part of the country is still seeing growing numbers of cases,” said Dickens. “They're probably going to have to take action to pull back from re-opening and people are gonna need economic support.” 4769

The drop in gun sales has lead to deep job cuts at Sturm RugerOn Wednesday, the company reported a 21% sales decline for 2017. Thursday it disclosed that it has cut 700 jobs, or more than a quarter of its staff, over the last 13 months. That leaves it with 1,750 workers."When we reduced production in 2017, we had to make some difficult decisions," said CEO Chris Killoy, on a call with analysts Thursday. Many of the jobs were eliminated through attrition. The company also had 320 temporary employees a year ago who have since left the company. In January, the company needed to further reduce staff, prompting it to lay off an additional 60 workers.Gun sales have been sharply lower across the industry since President Donald Trump was elected. Fears that Hillary Clinton would win the presidency and seek tougher gun control laws drove record sales through 2016, and encouraged retailers to stock up on inventory. With the election of Trump and Republicans in control of both houses of Congress, those fears greatly abated.Killoy said that 2017 FBI background checks, which correspond roughly to purchases, fell 11%. Retailers also cut back on purchases to reduce inventory."2017 was a challenging year for the firearm industry," Killoy. But he said as a result of the job cuts, "we're better positioned to compete in 2018."There has been more talk about gun control in the week since the shooting of 17 students and staff at a Florida high school, led by many of the students and families from that school.President Trump and some Republicans, including Senator Marco Rubio of Florida, have voiced new support for some gun control measures. But it's too soon to say whether those efforts will affect gun sales.Killoy did not mention the gun control debate during his conference call, although he did express sympathy for victims of the Florida shooting."Like all Americans, we struggle with the shock and sadness of these terrible events," he said.Sturm Ruger is not the only company to report a drop in sales. Overall the industry has reported a sales decline of more than 0 million in 2017.Gun maker Remington has warned it plans to file for bankruptcy protection soon. Killoy was asked about whether Sturm Ruger would be interested in buying Remington, given that it has a strong balance sheet. Ruger's cash on hand fell by nearly million during the year, but it still has .5 million and no debt. He wouldn't rule out a deal for Remington, but wouldn't comment on it directly."We're watching that closely," he said the coming bankruptcy case. "We wish them well going through that process. With million cash on hand, it may provide some opportunities down the road." 2727