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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

LOS ANGELES, July 18 (Xinhua) -- The spacecraft Dawn of the National Aeronautics and Space Administration (NASA) has returned the first close-up image of the giant asteroid Vesta after entering its orbit for the first time last week, the Jet Propulsion Laboratory (JPL) announced on Monday.The image taken for navigation purposes shows Vesta in greater detail than ever before, said JPL in Pasadena, California.On July 15, Dawn became the first probe to enter orbit around an object in the main asteroid belt between Mars and Jupiter.When Vesta captured Dawn into its orbit, there were approximately 9,900 miles (about 16,000 kilometers) between the spacecraft and the asteroid.Vesta is 330 miles (about 530 kilometers) in diameter and the second most massive object in the asteroid belt.NASA's Dawn spacecraft obtained this image with its framing camera on July 17, 2011. It was taken from a distance of about 9,500 miles (15,000 kilometers) away from the protoplanet Vesta. Each pixel in the image corresponds to roughly 0.88 miles (1.4 kilometers). Ground- and space-based telescopes have obtained images of Vesta for about two centuries, but they have not been able to see much detail on its surface."We are beginning the study of arguably the oldest extant primordial surface in the solar system," said Dawn principal investigator Christopher Russell from the University of California, Los Angeles, which is responsible for Dawn's mission science. " This region of space has been ignored for far too long. So far, the images received to date reveal a complex surface that seems to have preserved some of the earliest events in Vesta's history, as well as logging the onslaught that Vesta has suffered in the intervening eons."Vesta is thought to be the source of a large number of meteorites that fall to Earth. Vesta and its new NASA neighbor, Dawn, are currently approximately 117 million miles (about 188 million kilometers) away from Earth. The Dawn team will begin gathering science data in August.Observations will provide unprecedented data to help scientists understand the earliest chapter of the solar system and pave the way for future human space missions, according to JPL."Dawn slipped gently into orbit with the same grace it has displayed during its years of ion thrusting through interplanetary space," said Marc Rayman, Dawn chief engineer and mission manager at NASA's JPL. "It is fantastically exciting that we will begin providing humankind its first detailed views of one of the last unexplored worlds in the inner solar system."Although orbit capture is complete, the approach phase will continue for about three weeks. During approach, the Dawn team will continue a search for possible moons around the asteroid; obtain more images for navigation; observe Vesta's physical properties; and obtain calibration data.In addition, navigators will measure the strength of Vesta's gravitational tug on the spacecraft to compute the asteroid's mass with much greater accuracy than has been previously available, according to JPL.Dawn will spend one year orbiting Vesta, then travel to a second destination, the dwarf planet Ceres, arriving in February 2015. The mission to Vesta and Ceres is managed by JPL for the agency's Science Mission Directorate in Washington.Dawn is a project of the directorate's Discovery Program, which is managed by NASA's Marshall Space Flight Center in Huntsville, Alaska.

SUVA, July 25 (Xinhua) -- There are 400,000 people suffering from anaemia in Fiji with a total of population at about 800,000 people, according to the Health Ministry on Monday.Health Minister Doctor Neil Sharma told media that currently 60 per cent of children less than five years old are iron deficient, 40 per cent of women lack iron while 20 per cent of men suffer from iron deficiency in the island nation.Sharma, therefore, called on every family to grow local, eat local and move back to our traditional food habits, telling anaemic, "Do not forget to take your iron tablets."National Advisor Non-Communicable Diseases, Dr Isimeli Tukana also told media on Monday that strategies would include implementing the Food and Health Guidelines for the country in all clinics.All females are supposed to take their iron medication while all pre and primary school children will be given iron supplementation, he added.According to Fiji's Agriculture and Nutrition Department, the island nation, which is in transition towards increasing industrialization, is facing nutritional problems associated with both under-nutrition and over-nutrition.Lack of access to food due to economical shortages is one of the major causes of malnutrition in the country as one quarter of the population is living below the poverty line and most are living in illegal squatter settlements in search of employment and educational opportunities in urban areas.The problem of over-nutrition, on the other hand, may be associated with the change in the consumption patterns towards a diet high in energy but low in fibre, vitamins and minerals and a sedentary lifestyle.

SAN FRANCISCO, Sept. 13 (Xinhua) -- Researchers in San Francisco, U.S. have found in a latest study that bisphenol A (BPA) and methylparaben, two chemicals commonly used in consumer products, can interfere with the breast cancer drugs, local media reported on Tuesday.In the study, doctors from California Pacific Medical Center in San Francisco found that healthy breast cells from high-risk patients started to find ways to bypass breast cancer drugs after they were exposed to BPA and methylparaben in the lab.The cells exposed to the two chemicals kept growing and didn't die after they were introduced with Tamoxifen, a current standard drug therapy for female breast cancer and most common used treatment for male breast cancer, Dr. William Goodson, lead author of the study, told San Francisco Chronicle.Goodson said that BPA and methylparaben not only mimic estrogen 's ability to drive cancer, but appear to be even better than the natural hormone in bypassing the ability of drugs to treat it. The finds have been published online in the British medical journal Carcinogenesis.The research shows more evidence of safety issues of BPA, a chemical primarily used to make plastic baby bottles, food containers, household electronics and etc, as well as the less known methylparaben, a chemical preservative used in cosmetics and other personal care products.The researchers noted that the breast cancer rates have been growing by about the same amount in men as in women over the past three decades. Scientists have been looking at environmental causes for the disease and wondering where the hormones are coming from.Goodson said BPA and methylparaben are used so widely and even found in household dust, noting that it is still unknown whether the effects of exposure to the chemicals are reversible.Since 2008, several governments issued reports questioning the negative health effects of BPA, especially raising concerns regarding exposure of fetuses, infants and children. BPA use has been banned in baby bottles in a lot of countries and regions.As for methylparaben, the U.S. Food and Drug Administration said on its website that "at the present time there is no reason for consumers to be concerned about the uses of cosmetics containing parabens (including methylparaben)."

BEIJING, Aug. 12 (Xinhuanet) -- A Connecticut woman who was savagely attacked by a pet chimpanzee and had her face deformed in 2009 was shown on TV with a new face Thursday.TV pictures revealed Charla Nash’s new nose, lips and eyelid, which were transplanted in May by doctors at the Brigham and Women’s Hospital in Boston.Nash said to the viewers that she can move her mouth, smile and smell. Her daughter Brianna added that her mother can even talk and eat better now.Dr. Bohdan Pomanhac led a 30-member surgical team to complete the face transplant in 20 hours. The team also transplanted two hands but these were later removed due to blood flow problem when Nash suffered pneumonia.Nash’s friend Sandra Herold owned a 15-year-old chimpanzee named Travis that attacked without any provocation when Nash was visiting Herold.Travis simply went berserk and could not be stopped even after Herold stabbed it with a kitchen knife. It would only let go of Nash after the police arrived and shot it dead.