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Moderna announced on Thursday that it had enrolled 30,000 participants in its Phase 3 COVID-19 vaccine trial, with more than 11,000 of those participants from communities of color.More than 25,650 participants have already received their second vaccination, the company said in a press release.The company added that the study also includes 7,000 participants over the age of 65.“Completing enrollment of the Phase 3 COVE study is an important milestone for the clinical development of mRNA-1273, our vaccine candidate against COVID-19," said Stéphane Bancel, Chief Executive Officer of Moderna in the news release. "We are indebted to all of the participants in the study. We would also like to thank the investigators and our partners at clinical trial sites, including our partners from PPD and the NIH, as well as the dedicated Moderna team for their support in completing enrollment. Moderna is committed to rigorous scientific research and the highest data quality standards. We will continue to work in collaboration with regulators to advance mRNA-1273, which we hope will help defeat the COVID-19 pandemic.”CNN reported that for Moderna to apply to the FDA for emergency use authorization, the following three things need to happen:53 of the 30,000 participants would need to become sick with COVID-19, which is expected to occur in the second half of November.40 of the 53 participants who do become ill with COVID-19 need to have received the placebo, which would show that the vaccine is 75% effective.Make sure enough time has passed to see if participants develop side effects.According to CNN, Moderna is the first company to start US clinical trials of a COVID-19 vaccine. 1696
NBA commissioner Adam Silver said Tuesday that he believes that the league's next season won't begin until 2021."We said a week ago or so that the earliest we would start is Christmas of this year," Silver told sportscaster Bob Costas during an appearance on CNN Tuesday. "But the more I'm learning and listening to Dr. Fauci this morning, I continue to believe that we're going to be better off getting into January."The NBA season typically tips off in October, with the NBA Finals culminating in June. However, the current 2019-2020 season was delayed for several months due to the COVID-19 pandemic, and the league is currently is still in the midst of the conference semifinals.In addition, Silver said Tuesday that it's the league's goal to play a standard 82-game season and playoffs in 2021."Further, the goal would be to play games in home arenas in front of fans, but there's still a lot we need to learn in terms of rapid testing, for example. Would that be a means of getting fans into our building? Will there be other protections?" Silver said.Upon restarting its season in July, the NBA opted to hold all games and board all players, coaches and team personnel at the ESPN Wide World of Sports Complex at Disney World. Players and coaches must remain at the resort at all times in order to be eligible to play. Only about two-thirds of teams continued play in the 2020-21 season, and a seeding round was conducted before the standard playoffs began.MLB and the NFL chose to play games in home stadiums with limited or no attendance upon the start of their seasons. Silver says he hopes to learn from those sports before making a final decision on the 2021 season."There's a lot of new information out there in the marketplace that we're looking to absorb. But the goal is to play a standard season," Silver said. 1835

Months of isolation and social distancing have taken their toll on Americans. But for the 30 million struggling with eating disorders, that stress can make them especially vulnerable.Mental health experts say as social distancing enters its fourth month, they’ve seen a dramatic spike in people seeking assistance. The good news, they say, is that there is help.Growing up in a conservative south Texas family, Eric Dorsa says not fitting a stereotypical masculine identity drove him into a dangerous relationship with food.“I developed an eating disorder as a way to cope with emotions and thoughts and feelings about myself that I couldn't express as a child,” said Dorsa.After 13 years of recovery, it’s still a battle.“It was the hardest thing I've ever done,” said Dorsa. “It is like a giant car crash going off in the middle of your life and you have no choice but to deal with it.”Dr. Ellen Astrachan-Fletcher is the clinical director of the Eating Recovery Center in Chicago. The international center treats eating disorders like anorexia, bulimia and binge-eating.“Does this pandemic and the isolation contribute to worsening difficulties with eating disorders? Absolutely 100%,” said Astrachan-Fletcher.She says for millions suffering from eating disorders, the months-long lockdowns and isolation from support systems is amplifying the problem.With grocery stores not stocking certain products, experts say that could be a trigger for people who need that normal routine and those specific food brands to help keep them on their recovery track.“The reality is we have to be flexible in this time because due to the pandemic things are not what we expect,” said Astrachan-Fletcher.People turning to food for comfort and social media messaging about weight gain are not helping.“When someone starts engaging with an eating disorder, they tend to isolate and that feeds the eating disorder,” said Astrachan-Fletcher. “So, the isolation and pushing loved ones away is one way the eating disorder grows.”The National Eating Disorders Association says it has seen a 74% increase in calls to their help line during the pandemic as compared to the same time last year.“Even though sometimes it feels like we're alone, you don't have to be and there are lots of people here to be there with you,” said Astrachan-Fletcher.Astrachan-Fletcher says it’s important to seek professional help, take a friend or family member with you when you go to the grocery store, and set up virtual online dates for meal-times or snack breaks.Dorsa says it’s important to find your helpers.“You're not alone and you're enough just as you are,” he said. “You don't have to show up any other way other than with what you have. And let people help you find the next steps for you.” 2769
MILWAUKEE -- A suspicious package investigation in downtown Milwaukee took an unexpected turn Monday when a bystander suddenly walked up to the item in question and began rummaging through it, prompting investigators to tackle him. The backpack was reported shortly before 7 a.m., prompting a response by Milwaukee Police and the bomb squad.Video shows the man crossing the police tape, walking up to the backpack and dumping out the contents. It’s not clear if the man had any connection to the investigation. Police have not released any other information at this time. 614
MOHEGAN LAKE, N.Y. — Angelina Friedman, a 102-year-old nursing home resident, recently survived her second bout with COVID-19, according to her daughter Joanne Merola."Not only has she beaten COVID at 101, she's beaten it at 102," Merola said.Friedman also has the unique distinction of living through two global pandemics.During the 1918 pandemic, Angelina Sciales was born on a passenger ship taking immigrants from Italy to New York City."She was born on a ship coming from Italy during the Spanish flu," Merola said earlier this year. "Her birthday was Oct. 18, 1918."Angelina's mother died giving birth on the ship."She was helped by her two sisters," Merola said of her mother.When Angelina's father reunited with his daughters in New York, he took them to live in Brooklyn."She was one of 11 children," Merola said. "She's the last one surviving."Angelina eventually married a man named Harold Friedman. The couple battled cancer later in life, but only Angelina overcame the disease.She's lost most of her hearing and her vision is bad, but she's retained her zest for life.Friedman, a resident of the North Westchester Restorative Therapy and Nursing Center, battled COVID-19 most recently in October, according to her daughter.Her first bout with the virus happened in March when she was taken to the hospital for a minor medical procedure.When she initially tested positive for COVID-19, the procedure was postponed and Friedman spent a week in the hospital. She then returned to the nursing home and was isolated in her room.After running a fever on and off for several weeks, Friedman finally tested negative for coronavirus on April 20.At the time, Friedman's daughter received a late-night phone call from nurses. They said Friedman was doing great, that she was eating again and looking for yarn for crocheting."My mother is a survivor," Merola said in April. "She survived miscarriages, internal bleeding and cancer."Six months after that first COVID-19 diagnosis, Friedman's daughter said she received a call from the nursing home in late October, "to tell me she tested positive again.""She had symptoms — fever, a dry cough," Merola said. "...they gave her a bunch of meds. They thought she might also have the flu."More staff and residents at the nursing home were getting sick, according to Merola, so the older residents were put in isolation.Merola said she got daily updates on the situation, and on Nov. 17 she received great news."My invincible mother tested negative," she said.After another test came back negative, Friedman was moved out of isolation and back into her regular room.Merola said she attributes her mother's survival to "an iron will to live.""She's not the oldest to survive COVID, but she may be the oldest to survive it twice," she said.This story was originally published by Mary Murphy on WPIX in New York City. 2868
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