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SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648

SAN DIEGO (KGTV) - It looks like a mini farmer's market: fresh fruits, vegetables, herbs, even flowers.All of it coming from home gardens like Rosemary McElroy's. She and her fiancé Kevin Rookey love having fresh produce in their own backyard but, "we realized everyone has way more produce when you grow it than you can actually consume."The couple posted on the Nextdoor App, thinking maybe other neighbors wanted to trade.RELATED: Making It in San Diego: Reverse meal planning saves woman hundreds on grocery billThe response was so overwhelming, McElroy decided to organize a meet-up."This is around Lake Murray, let's host it at Lake Murray, we'll call it Lake Murray Produce just to give it a name," said McElroy.So far they've done three swaps, once a month for about an hour. Each time more and more people show up, able to walk away with organic produce for free and make sure nothing goes to waste.RELATED: Ocean Beach duo cook up 'foodie' meals on a day budget"When you have 500 oranges on a tree and you're not eating THem you feel guilt, right? So I think it’s about relieving guilt, too," said McElroy.If you'd like to know more or participate, click here. 1181

SAN DIEGO (KGTV) — It’s decision time for the San Diego Padres, who are trying to choose the right candidate to replace fired manager Andy Green.Widespread reports, confirmed by 10News, indicate the Padres have narrowed their search to two very different candidates.The first is 38-year-old Jayce Tingler, who has worked in a variety of coaching and front office roles with the Texas Rangers, but has no Major League managerial experience.RELATED: Padres' Yates wins Baseball Digest's top reliever awardThe second is 67-year-old Ron Washington, who managed the Texas Rangers to back-to-back World Series appearances in 2010 and 2011, before stepping down in 2014. He's currently the 3rd base coach for the Atlanta Braves.The Padres have previously stated a preference for an experienced manager, which could give Washington the edge. But the decision largely rests on the shoulders of general manager A.J. Preller, who is said to be high on Tingler’s ability to communicate with players in English and Spanish along with his understanding of baseball analytics.The timing of the decision remains unknown but both candidates were in San Diego this past week for second interviews with club officials.RELATED: Padres to unveil new 2020 uniforms in NovemberThe team fire Green days before the conclusion of the regular season. Green manned a 274-366 record during his four seasons with the team.Following Green's dismissal, Preller said "the biggest thing I know is we’re better than what we’ve shown," during a media conference. He added that he felt the team needed a "different voice, different direction" moving into the 2020 season."It's a big decision. You don't want to be sitting here in this spot again," Preller told media on hiring a new manager. "It'll be a good process. It'll be detailed." 1808

SAN DIEGO (KGTV) — Internationally, night markets invoke a sense — and smell — of wonder in its visitors, from delicious street cuisine to unique crafts to entertainment.The Convoy District hopes to capture that magic for San Diegans during San Diego Night Market at SDCCU Stadium. Saturday (4 p.m. - 12 a.m.) and Sunday (4 p.m. - 9 p.m.), the stadium expects 15,000 visitors hoping to experience that magic of bustling nighttime markets in big cities throughout Asia.The market first launched in 2013 at Kearny Mesa's Zion Market, only expecting about 2,000 attendees. To their surprise, 10,000 people showed up and have helped turn the market into an annual event to show off San Diego's diverse culture and history.RELATED: 10 must-eat restaurants on San Diego's Convoy StreetVisitors can enjoy food from local Convoy Street stops like Cross Street Chicken, HI Street Kitchen and Tap, and Simsim Outstanding Shawarma. Plus, food trucks turning out more delectable eats.On two entertainment stages, the San Diego Lucky Lion Dancers will perform, along with Naruwan Taiko drummers, Lemon Candy KPop dancers, and several other acts.And vendors will be out showcasing their handmade crafts and art for purchase throughout the market.Admission is and parking is free at the stadium. A "I Love Convoy" lanyard and pin ticket can also be purchased for , allowing unlimited entrance to the market throughout the weekend and promising Convoy Street deals in the future.Check out the full food and entertainment lineups here. 1532

SAN DIEGO (KGTV) — Local research organizations and San Diego County are teaming with the CDC to expand the genome sequencing of COVID-19. That data gives county leaders important information to drive decision-making to help slow and control the spread of the virus.“The virus is constantly evolving and trying to figure out the best way to spread through our population. And is it does that, it changes a little bit,” said Dr. Louise Laurent a professor at UC San Diego, which is part of the team, along with Scripps Research.Laurent says that studying changes in the virus can help identify which cases are connected to each other and which are not. The county can use that information to understand what measures are working, where there are significant outbreaks, and whether new measures are needed to stop those outbreaks.The county’s top epidemiologist, Dr. Eric McDonald, tells ABC 10News that the data shows that through testing and contract tracing, efforts to control outbreaks have generally been effective. “It looks like many of the instances of individuals who are infected don’t result in too many other infections. We don’t have lots of big clusters of the same exact strain,” McDonald said.The data also shows that while the restrictions and actions taken by the county have been effective in controlling outbreaks, COVID-19 continues to spread in San Diego through travel. “What we found is that San Diego has been hit many different times and viruses from other places have come to San Diego,” Laurent said. “We don’t want to be an isolated place. We want to interact, right? We’re just that kind of place. It makes us vibrant. It makes us an interesting place to be. But that also makes us vulnerable.”The research team recently received a .5 million contract from the CDC to expand its work. 1823

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