宜宾玻尿酸丰鼻唇沟(宜宾双眼皮好的整形医院) (今日更新中)

A genetic analysis of COVID-19 patients suggests that blood type might influence whether someone develops severe disease.Scientists who compared the genes of thousands of patients in Europe found that those who had Type A blood were more likely to have severe disease while those with Type O were less likely.Wednesday’s report in the New England Journal of Medicine does not prove a blood type connection, but it does confirm a previous report from China of such a link.“Most of us discounted it because it was a very crude study,” Dr. Parameswar Hari, a blood specialist at the Medical College of Wisconsin, said of the report from China. With the new work, “now I believe it,” he said. “It could be very important.”Other scientists urged caution.The evidence of a role for blood type is “tentative ... it isn’t enough of a signal to be sure,” said Dr. Eric Topol, head of the Scripps Research Translational Institute in San Diego.The study, involving scientists in Italy, Spain, Denmark, Germany and other countries, compared about 2,000 patients with severe COVID-19 to several thousand other people who were healthy or who had only mild or no symptoms. Researchers tied variations in six genes to the likelihood of severe disease, including some that could have a role in how vulnerable people are to the virus. They also tied blood groups to possible risk.Most genetic studies like this are much larger, so it would be important to see if other scientists can look at other groups of patients to see if they find the same links, Topol said.Many researchers have been hunting for clues as to why some people infected with the coronavirus get very ill and others, less so. Being older or male seems to increase risk, and scientists have been looking at genes as another possible “host factor” that influences disease severity.There are four main blood types — A, B, AB and O — and “it’s determined by proteins on the surface of your red blood cells,” said Dr. Mary Horowitz, scientific chief at the Center for International Blood and Marrow Transplant Research.People with Type O are better able to recognize certain proteins as foreign, and that may extend to proteins on virus surfaces, Hari explained.During the SARS outbreak, which was caused by a genetic cousin of the coronavirus causing the current pandemic, “it was noted that people with O blood type were less likely to get severe disease,” he said.Blood type also has been tied to susceptibility to some other infectious diseases, including cholera, recurrent urinary tract infections from E. coli, and a bug called H. pylori that can cause ulcers and stomach cancer, said Dr. David Valle, director of the Institute of Genetic Medicine at Johns Hopkins University.Bottom line: “It’s a provocative study. It’s in my view well worth publishing and getting out there,” but it needs verification in more patients, Valle said.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3086

A Las Vegas personal injury lawyer has been arrested in a theft case stretching back years.Beginning in March, Las Vegas Metropolitan Police Department detectives began to receive reports from multiple victims regarding a local personal injury lawyer. Victims that have to this date filed police reports, all allege that their personal injury attorney, later identified as 53-year-old Matthew Dunkley, misappropriated financial settlements the victims were to receive as a result of their cases in which Dunkley represented them.The reports indicated that Dunkley, in addition to misappropriating the settlements to the victims, also took money from the insurance companies that were intended to cover the victims’ medical bills. The victims never received their settlements and are now being held personally responsible for the unpaid medical bills. On Monday, Dunkley was located by detectives with the LVMPD Major Violators Section Repeat Offender Program and taken into custody. He was transported to the Clark County Detention Center where he faces at least 39 counts of theft.As of his arrest, detectives believe approximately .8 million was taken from victims.Detectives are asking any additional clients of Dunkley Law who may be awaiting settlements and were victimized by this scheme, to contact the LVMPD Theft Crimes Bureau at 702-828-3483.Clear Counsel Law Group has assumed some of the cases, but these clients may still have been victimized by Dunkley.In 2017, the Nevada bar asked Clear Counsel to assist Mr. Dunkley's former clients with open legal matters. Clear Counsel Law Group has no other relationship with Mr. Dunkley.Many of these cases were from personal injury cases that had occurred as far back as 2012, and one of the incidents involved a 5-year-old child who had been the victim of a dog attack. These victims also filed complaints with the State Bar of Nevada.According to the website of the State Bar of Nevada, Dunkley was suspended from practicing law in October of 2017. 2047

A consumer advocacy group is warning parents of what it calls "dangerously high" levels of a chemical called boron in popular slime toys marketed to children -- although an expert disputed the findings and said the warning is overblown.The warning was contained in the annual report by the?US Public Interest Research Group Education Fund. The "Trouble in Toyland" safety survey was published Tuesday ahead of the major holiday shopping season.The group noted "toys are safer than ever before," but that more work needs to be done to make them safer. PIRG's report highlighted the potential hazards of slime, toys with possible choking hazards and ones that could violate children's privacy by sharing data."With hundreds of new toys hitting the market every year, our survey of only 40 toys suggests there may be other potentially dangerous toys slipping through existing protections or worthy of further investigation," the group said.The group singled out six popular slime products for what it described as containing "dangerously high boron content." Boron is a nonmetallic element, and compounds of it, such as borax, have been used in products for decades, ranging from detergents to roach poison. The US PIRG Education Fund said it found that "significant concentrations of boron, as high as 4,700 parts per million (ppm) in popular slime toys.""Young kids are known to put everything in their mouths and when it comes to slime that could have serious consequences," said Adam Garber, the lead author of the report. "These high levels of boron can cause nausea, vomiting and long term reproductive health issues. Parents should closely monitor their kids when playing with this toy and call poison control if any is eaten."Garber added, "We should protect children by ensuring every package has appropriate labels moving forward and determine health-based standards to ensure children don't end up in the emergency room from their holiday gift."The United States does not have established standards on limits for boron in products. The Centers for Disease Control and Prevention says exposure to large amounts of boron -- about 30 grams of boric acid -- "over short periods of time can affect the stomach, intestines, liver, kidney, and brain and can eventually lead to death." Fatal doses for children are estimated to be 5 to 6 grams, according to the?Environmental Protection Agency.PIRG noted the European Union has a limit of 300 ppm for boron and that there should be a "full-fledged investigation to determine if limits should be established" in the US. "Policymakers should continue to evaluate new threats, such as boron, and ensure the Consumer Product Safety Commission has the funding and authority to protect the public," the report said.However, Rick Sachleben, a member of the American Chemical Society who has experience with boron, said it's important to distinguish the fact that "all forms of boron are not equally toxic." He said sodium borate, the known component used in slime, has "very low toxicity.""You'd almost have to do something beyond reason to make it toxic," he said, adding that a child would need to eat "multiple containers" before it reached toxic levels."The health risks are relatively low and can be controlled by telling your kid: 'If you eat the slime, I'm not going to buy you any more," Sachleben said.Sachleben wasn't the only one to take issue with the PIRG report.Wonder Workshop CEO Vikas Gupta told CNN that information about his company's product in the report was categorically false. The PIRG report, citing an investigation by the Mozilla Foundation, said Wonder Workshop's Dash robot "shares your information with third parties.""That is absolutely incorrect," Gupta said. "We don't collect any personal identifiable information from children, and we do not share any information from the apps or the software or robots to any third-party ever. None of that happens."Amazon, which had its Amazon Fire HD Kids Edition cited for its possible sharing of data, said the product is in full compliance with the Children's Online Privacy Protection Act. "We do not share children's data with third parties," Amazon said in a written statement.The report also said another popular toy -- the Hatchimals Fabula Forest; Hatching Egg with Interactive Tigrette -- had "no choking hazard label" in its listing on Walmart.com, although the photograph of the product has a choking warning on the front of the box.Garber said that wasn't good enough, that the "law requires online sites to provide warning labels directly on the site, not just on pictures or on the packaging, so parents are warned prior to purchase."According to PIRG, the Consumer Product Safety Commission has recalled more than 40 children's products in the last year, totaling more than 2.7 million units.Balloons cause more choking deaths among children than any other toy, according to the PIRG report. The group found three balloon packages that are either marketed to young children or are not labeled properly with choking hazard warnings.The six slime products mentioned in the report were:-- Kangaroos Original Super Cool Slime, which was found to contain "4700 ppm boron concentration. The EU limit is 300 ppm."-- Kidsco Glow in The Dark Slime with "4600 ppm boron concentration."-- Toysmith Jupiter Juice Slime with "1900 ppm boron concentration."-- iBaseToy Fluffy Slime with "1500 ppm boron concentration."-- Haniex Soft Magic Crystal Slime with "1400 ppm boron concentration."-- Meland Fluffy Slime with "1100 ppm boron concentration."Garber said 5 grams of boron could prove fatal for a child, although "health impacts with boron appear at much lower levels" than that. He acknowledged "you'd likely have to ingest multiple containers to reach the fatal level" of boron, but he doesn't believe that should be the standard. 5896

A fifth person has died from his wounds as a result of Tuesday's Strasbourg Christmas market attack, the Paris prosecutor's office told CNN on Sunday.A gunman burst into the market in the evening hours Tuesday as crowds did their holiday shopping, killing three and wounding 13 more. The fourth victim, Antonio Megalizza, an Italian journalist who had been on life support since the attack, died on December 14, French authorities told CNN.CNN affiliate BFMTV reported that a 45-year-old man visiting from Thailand, an Afghan father of three who had been living in France for 15 years, and a man from Strasbourg also died in Tuesday's market attack.The authorities are calling the mass shooting a terrorist attack. Police killed the gunman Thursday night near the marketplace.The shooter, Cherif Chekatt, was known to prison officials for being radicalized and for his proselytizing behavior in detention in 2015, Paris prosecutor Rémy Heitz said, adding that he had been incarcerated multiple times in the past. French prosecutors said the suspect shouted the Arabic phrase "Allahu Akbar," meaning "God is greatest," at the time of the attack. 1152

A man is dead after falling off a ladder while cutting a tree branch following Hurricane Irma.Hillsborough County, Florida Fire Rescue responded to Puritan Road in Tampa, at approximately 2:54 p.m. on Thursday, after receiving a call about a person down.Upon arrival, firefighters found 60-year-old John Knight on the ground.According to a witness, Knight was cutting a tree branch when it hit him and knocked him off his ladder, causing him to fall between 20 to 25 feet.Firefighters pronounced Knight dead at the scene. 559

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