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LA JOLLA, Calif. (KGTV) — Police are on the hunt for a man who they say set a La Jolla home on fire before pointing a gun at construction crews. Friday morning, Teresa Zlokarnik woke up to an odd smell coming from across the street. “I don’t know where it was coming from, but I saw smoke, and I saw the firemen going into the house,” Zlokarnik said. For the last few months, she saw the home on the other side of the street go from rubble to almost done. But not anymore. At 9:45 a.m., San Diego Fire Rescue responded to an attic fire, set intentionally.“What? An arson? That’s scary. Oh my God,” Zlokarnik said. The homeowner, who asked not to be identified, claimed he knows who did it. “He didn’t show up for three days, and I fired him,” the homeowner said. The homeowner said he believes the suspected arsonist is a disgruntled former employee who was hired to work on the sheet rock. But when the man came to the site Friday morning and saw his replacements at work, he set the attic on fire. In his 40 years of renovating homes, the homeowner said he has never seen this kind of reaction from an employee, current or former.“He said, ‘My price is my price and if not, you are going to hear from me!’ So I heard from him this way,” the man said. He added that the new subcontractors were held at gunpoint. They waited until the suspect left to call 911.The home on Palomino Circle was supposed to be on the market July 1, 2019, for .9 million. But after what happened today, the homeowner said that an open house would have to be pushed back.“Our heater is gone, the electricity is gone, the plumbing is probably damaged,” he said. The homeowner and his company are now playing catch-up. As for Zlokarnik, her sense of security in her neighborhood is now shattered. “Oh my God, he’s out on the loose? God, I am scared. I am locking my doors,” Zlokarnik said. San Diego Police have not caught the suspected arsonist. 1932

Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched."  6969

LA JOLLA, Calif. (KGTV) - San Diego photographers, mark your calendars for Scrippshenge. Named for the ancient British site Stonehenge, where the sun lines up among ancient stones on the solstice, the sun lines up with the gap in La Jolla’s Scripps Institution of Oceanography pier on certain days of the year. The natural phenomenon makes for spectacular photos. This summer, Scrippshenge is set to take place August 7 - 9, according to the Photo Ephemeris app. “You might even get the shot on Aug 10/11 also, probably with a partially set sun,” says Stephen Trainor of Crookneck Apps. “You'll see the sunset line is ever so slightly to the north of the pier center: that's what you need, because sunset is the moment the sun disappears below the horizon, hence in order to frame the setting sun between the legs of the pier, it still needs to be just above the horizon, and therefore true sunset has to be just slightly to the north,” says Trainor. If you miss Scrippshenge, you can still enjoy the sunset at one of SIO’s Green Flash Concerts.RELATED: New Yorkers celebrate Manhattanhenge 1098

LAKE HODGES (KGTV) - A San Diego woman tells 10News she was bit by a tick at Lake Hodges and diagnosed with Lyme disease a month later. Sheila Greer has hiked Lake Hodges for 33 years she tells 10News, "I've never had an issue." Greer hiked the same trails at the end of June. She says that's when she believes she got bit by a tick, "The trail had bushes coming up that I would have to brush through and something in the back of my mind said, that's a prime area for ticks. But, I discounted it because I've hiked there for 33 years." Greer got diagnosed with Lyme disease a month after the tick bite. Usually, tick bites have a ring around the bite but her's did not. For that reason, she thought it was a spider bite and waited to see a doctor. She tells 10News she struggled with neck pains and unbearable headaches. Greer finally got a Western Blot test which confirmed her diagnosis. The County of San Diego tells 10News, "Lyme disease is rare San Diego County and we have not had a positive tick found in many years." Because Greer thought she had a spider bite, she didn't know to look for a tick to bring to the county for testing. Greer has been seeing a doctor regularly and is now on antibiotics, "I'm taking antibiotics and I'll be taking antibiotics for a minimum of three months, maybe much longer." 1322

Ladies & gents, here’s the cast of our new @NBC comedy, #YOUNGROCK. A series based on my wild and unpredictable childhood & formative years growing up. Bradley Constant will take on playing me at 15 and kicking puberty’s ass ??????Can’t wait for you guys to watch! @sevenbucksprod pic.twitter.com/1pUY1gf9XN— Dwayne Johnson (@TheRock) October 1, 2020 366