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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Self-driving trucks carrying U.S. postal mail will soon be on roadways from Phoenix to Dallas.TuSimple, a startup based in San Diego, is the maker of the trucks that will haul mail to and from USPS facilities in the two cities, 240

Scenes of chaos erupted at Hong Kong's airport on Tuesday evening as riot police clashed with protesters who continued to block security gates at one of the world's largest travel hubs.The police made their first significant appearance at the airport since protests began there five days ago, with at least five police buses arriving at the airport after 10:30 p.m.Protestors scrambled to set up barricades as police officers left the buses and entered the airport. Riot police appeared soon after, amassing outside the airport terminal and clashing with demonstrators.The violence came after Hong Kong's Airport Authority announced that all check-in services would be suspended for another night, due to terminal operations being "seriously disrupted.""Members of the public are advised not to come to the airport," the authority said in a statement. All outbound flights which have not yet completed the check-in process have been canceled. 954

Summer break is here for many kids across the country. While that means a break from class, for some students it means an end to the free and reduced school lunch they depend on during the school year. However, one Colorado community is making sure its children don’t go hungry this summer. “I feel good. I love it,” says Salina Sanchez. Sanchez operates a retired bus that was turned into a mobile café. Sanchez is part of the team at Aurora Public Schools bringing free lunches to where students are. “Just giving the free meal and at least knowing that they're eating, and that, that's what's good,” Sanchez says. Across the country, 1 in 6 children in America live in households without consistent access to an adequate amount of food. In the Aurora Public Schools district, roughly 70 percent of students receive free or reduced lunch. In the past, the school provided lunches at school cafeterias during the summer, but getting to the school was a challenge for many students. Therefore, school officials decided to transform buses going out of service into bright, mobile cafés. “Just create a spot where they could come see us…for free,” says Stacey Bennett with the Aurora Public Schools Nutrition Services. “Not have to go into a building and just be more visible and take the food to them. Now, three mobile cafés serve students lunch during the week at several locations. It’s free to all children, whether they are students in the district or not. “It is a small gesture, but it has a huge impact,” Bennett says. For Sanchez, seeing the reaction from the kids makes it all worth it. “I have like over 600 kids. I can say that they are mine, because I treat them all as if they were mine,” Sanchez says. 1729

Researchers in Germany have recently published a study finding that a small percentage of people have developed an addiction to shopping. The October 2019 study released in Comprehensive Psychiatry explores the addictive response to shopping. The study found that 1 in 20 of adults developed an addiction to shopping. The researchers dubbed the addiction as "buying-shopping disorder" (BSD), which "is characterized by extreme preoccupations with and craving for buying/shopping and by irresistible and identity-seeking urges to possess consumer goods."While the study looked at shopping more broadly, the researchers believe that the ability to shop online is feeding the addiction. "As e-commerce provides an important shopping environment, traditional BSD may migrate into the online retail market," the study states. "The internet offers a vast variety of shopping information and simultaneous access to many online stores, thereby meeting expectations for immediate reward, emotional enhancement and identity gain."To read more on the study, click 1065