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WASHINGTON, Dec. 12 (Xinhua) -- British scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. The findings, published Monday in the U.S. journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF -- the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.Scientists at the University of West England and the University of Bristol discovered that mutations in one specific cancer gene can control how splicing is balanced, allowing a master switch in the cell to be turned on. This master switch of splicing makes cancer cells grow faster, and blood vessels to grow more quickly, as they alter how VEGFs are put together.In experimental models, the researchers found that by using new drugs that block this master switch they prevented blood vessel growth and stopped the growth of cancers."The research clearly demonstrates that it may be possible to block tumor growth by targeting and manipulating alternative splicing in patients, adding to the increasingly wide armory of potential anti-cancer therapies," the authors said.
BEIJING, Dec. 27 (Xinhua) -- The People's Bank of China (PBOC), China's central bank, announced Tuesday that it is banning local regions, institutions or individuals from setting up gold exchanges apart from the existing Shanghai Gold Exchange and Shanghai Futures Exchange.The country also bans the establishment of any gold trading platforms in other exchanges, a statement on the PBOC website said.The statement said the country has ordered a cease to the building of any new gold exchanges or trading platforms. Those which have opened for business must cease operations.The ban came amid bigger risks in gold trading after some local regions, institutions and individuals grew enthusiastic in setting up gold exchanges and trading platforms in recent years as gold prices soared, which led to a surge of illegal practices due to inadequate management, the statement said.It added the central bank will work with the Shanghai Gold Exchange and Shanghai Futures Exchange to boost the healthy development of the country's gold trading market.

BEIJING, Jan. 7 (Xinhua) -- The two-day National Financial Work Conference concluded Saturday, laying out development plans for the financial sector in the coming five years, according to a statement released after the meeting.Chinese Premier Wen Jiabao was present at the conference and delivered a keynote speech.Such a conference is held every five years. Similar meetings were held in 1997, 2002 and 2007.
BEIJING,Nov. 9 (Xinhuanet) – Yinghuo-1, China's first interplanetary spacecraft, is set to hitch a ride with Russia's Phobos-Grunt Mars mission in the early hours on Wednesday, after a two-year delay.A Zenit-2SB rocket will carry Yinghuo-1 and Phobos-Grunt into space from the Baikonur Cosmodrome launch site in Kazakhstan.It is China and Russia's first joint Mars operation and also marks China's first voyage to the Red Planet, China Great Wall Industry Corp said in a news release on Tuesday.Yinghuo-1 will work in orbit with Phobos-Grunt for more than 12 months in collecting data on the Martian atmosphere.Both spacecraft will travel for more than 10 months before entering Martian orbit. During the trip, Yinghuo-1's power supply, communications and temperature gauge will be controlled from the Russian craft, scientists said.Both craft will orbit the planet three times before decoupling. The 106-kg Yinghuo-1 will circle Mars in an elliptical orbit, while Phobos-Grunt will actually land on Phobos, one of the two Martian moons, and bring back soil samples to Earth."The collaboration with Russia will enhance China's ability in deep space exploration, improve spacecraft design and development, and promote planetary exploration," said an unnamed official with the corp, a subsidiary of the China Aerospace Science & Technology Corp. Russia's Lavochkin Research and Production Association signed a cooperation contract, based on an agreement between the Chinese and Russian governments, with China Great Wall Industry Corp in 2007.Yinghuo-1, with a two-year lifespan, also has its own scientific goals.These include analyzing the planet's magnetic environment and ionosphere (upper atmosphere), taking images of topographical features and studying gravity fields on the Martian equator.Pang Zhihao, deputy editor-in-chief of the monthly publication, Space International, said China's focus on the planet's upper atmosphere is significant.Twenty detectors have explored parts of Mars, but most of them have looked for traces of life or water or places suitable for setting up colonies, he said.But studying the upper atmosphere is also vital if humans are to live on the planet, he said.The mission was set for October 2009, but later postponed to this year to enhance the reliability of the project.Only the United States, the former Soviet Union and the European Union have succeeded in landing probes on Mars. Five are in operation, four belong to the US and one belongs to the EU.At least 21 probes sent to the planet have failed. The Shanghai Academy of Spaceflight Technology under the CASC, which designed Yinghuo-1 in 23 months, said that the satellite posed a major technological challenge as the furthest space destination for China before had been the moon. The moon's average distance from Earth is about 384,000 km. The distance between Mars and Earth, depending on orbits, ranges from approximately 55 million km to about 350 million km.Yinghuo-1 will have to endure periods in the freezing dark side of the planet.It underwent simulated tests that matched the Martian temperature, - 260 C.Because of the distances involved, the satellite cannot rely on ground control to adjust position. It will rely on its own onboard computer, scientists said.
HELSINKI, Nov.23 (Xinhua) -- Nokia Siemens Networks is planning to cut its workforce by 17,000 worldwide by the end of 2013, the company said in a statement on Wednesday in Espoo, Finland.The company said the measures are part of an extensive global restructuring program, in which it will focus on mobile broadband and services."We need to take the necessary steps to maintain long term competitiveness and improve profitability in a challenging telecommunications market," said the company's Chief Executive Rajeev Suri in the statement.Rajeev Suri called the job cuts regrettable but necessary, and said the company would provide support for individuals and communities affected by the cuts, but defended the decision on economic grounds.Nokia Siemens is aiming to cut operating expenditures by around a billion euros over two years.Some 74,000 people currently work for the Espoo-based company in 150 countries, around 7,000 in Finland. The company will announce the geographical distribution of the job cuts later on.
来源:资阳报