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The Senate on Wednesday will hold a hearing regarding the safety of vaccines, which will feature appearances by Surgeon General Dr. Jerome Adams and National Institutes of Health Director Dr. Francis Collins.The hearing, hosted by the Senate HELP Committee, will discuss the role of vaccines in preventing infectious disease outbreaks and protecting public health.Wednesday's hearing will also include information on a potential COVID-19 vaccine.Top U.S. health experts like Dr. Anthony Fauci say they are cautiously optimistic that there will be enough evidence to grant Emergency Use Authorization to top vaccine candidates by the end of 2020. However, recent polls indicate that some Americans remain skeptical about vaccines.A recent CBS News poll indicates that just 21% of American voters would receive a COVID-19 if one were made available at no cost. That's down from about 30% earlier this year. Two-thirds of those polled say they feel a vaccine would be "rushed" if a vaccine were made available this year.Fauci has said that if a potential vaccine is 75% effective against the virus, it still may not be effective in promoting inoculation levels necessary for "herd immunity" in the U.S. due to Americans' ongoing skepticism about vaccines.Nine vaccine makers banded together to sign a pledge on Tuesday to say that they will not seek Emergency Use Authorization for their vaccine candidates until scientific methods prove they are safe for widespread use. 1476

The Trump administration will end the protected immigration status of thousands of Central Americans who have been living in the US nearly two decades, urging Congress to act if it wants to spare those individuals from being uprooted.Department of Homeland Security acting Secretary Elaine Duke has decided to terminate Temporary Protected Status for Nicaragua with a 12-month delay, the department announced Monday night. DHS also said Duke has not been able to reach a decision on Honduras despite different agencies' input, triggering an automatic six-month extension. At the end of that six-month window, the homeland security secretary will make a decision to terminate or further extend the status.The Trump administration has signaled a desire to wind down the protections of Temporary Protected Status, which is an immigration status allowed by law for certain countries experiencing dire conditions, such as a natural disaster, epidemic or war. TPS protects individuals from deportation and authorizes them to work in the US. Without TPS, those individuals revert to whatever status they had previously -- which could leave large numbers as undocumented immigrants.In encouraging Congress to act if it wants to extend those protections permanently, the Trump administration echoed its move in ending the popular Deferred Action for Childhood Arrivals program, which protects hundreds of thousands of young undocumented immigrants brought to the US as children and which President Donald Trump decided to sunset this fall.Both decisions were due by Monday, as the status was set to expire January 5. There is a 60-days-in-advance requirement by law to make a determination on extending or terminating Temporary Protected Status.The roughly 5,300 individuals from Nicaragua affected by this decision have lived in the US roughly 20 years: To qualify for TPS, Nicaraguans must have been living in the US continuously since January 5, 1999, after Hurricane Mitch devastated the country.DHS officials told reporters that Duke did not yet have enough information to make a decision on the 86,000 individuals covered under the Honduran protections, which by law triggers a six-month extension. Hondurans also have to have been living in the US continuously since January 5, 1999 to qualify, also due to Hurricane Mitch.The move was being closely watched and heavily lobbied on both sides.Though the administration says it is evaluating each country on its own, it has been more aggressive than previous administrations in evaluating only whether conditions have improved from what triggered the initial designation, regardless of dire conditions continuing due to other causes. That has the support of conservatives like Senate Judiciary Chairman Chuck Grassley, who wrote DHS last week urging them to not perpetually renew TPS.In the next few months, the status of hundreds of thousands of TPS recipients will be up for decision. The Trump administration has already terminated the status for Sudan, extended protections for South Sudan, and given itself an extra six months to decide on protections for roughly 58,000 Haitians. That will be the next decision due, at the end of the month. When former Homeland Security Secretary John Kelly extended Haitian TPS another six months over the summer, he encouraged recipients to either apply for status under some other means or prepare to depart the US.In extending Nicaraguan protections for a final 12 months, DHS officials on a call with reporters urged those recipients to "seek an alternative lawful immigration status in the United States, if eligible, or, if necessary, arrange for their departure."Coming up early next year is also a decision for El Salvador, with roughly 260,000 people covered from that country, who have lived in the US more than 15 years.One official also called on Congress to act if they want individuals to remain permanently. Democrats have heavily lobbied DHS to preserve the protections, as have advocacy groups and business groups like the US Chamber of Commerce."Only Congress can legislate a permanent solution and provide those in an otherwise perpetually temporary status with a certain future," the official said.Democrats were quick to call out the administration's move. The Congressional Hispanic Caucus called on Congress to act following the administration's "reckless" action."The Trump administration's irresponsible decision to end TPS for Nicaraguans will tear apart families and upend the lives of these hard-working individuals," CHC Chairwoman Michelle Lujan Grisham said in a statement. "These immigrants have lived in the United States for nearly 20 years and have raised US citizen children, contributed to our economy and enriched our communities. Deporting families who are contributing to the economic and social fabric of our nation isn't leadership; it's a reckless and callous abuse of power."  4920

The U.S. Postal Service on Tuesday said it could not meet a federal judge’s order to sweep processing centers for undelivered mail-in ballots, arguing that doing so would disrupt its Election Day operations. U.S. District Judge Emmet G. Sullivan of Washington, D.C., gave the agency until Tuesday afternoon to search 27 facilities in several battleground areas for outstanding ballots and send out those votes immediately. In its response, the Postal Service said it had already conducted rounds of morning checks at all its processing hubs. Further, the agency said it has been performing daily reviews of all 220 facilities handling election mail and planned another sweep hours before polling places closed Tuesday. 726

The two children who were rescued from an RV after an hours-long chase ended in Kern County, California have been reunited with their mother. The Los Angeles County Sheriff's Office posted pictures on Twitter at about 2 a.m. Wednesday, showing the children with their mom at an office. LACSO says both children were unharmed following Tuesday's pursuit.  377

The Smithsonian National Zoo in Washington is welcoming its newest member — a baby Lowland gorilla.On Sunday, 15-year-old Calaya gave birth to a son, Moke — "junior" or "little one" in Lingala, a language spoken in Central Africa.“The birth of this western lowland gorilla is very special and significant, not only to our Zoo family but also to this critically endangered species as a whole,” said Meredith Bastian, the National Zoo's curator of primates, according to the Smithsonian. “The primate team’s goal was to set Calaya up for success as best we could, given that she is a first-time mother. Doing so required great patience and dedication on the part of my team, and I am very proud of them and Calaya.”According to the zoo, Cayala has been adjusting well to motherhood and has learned how to care for Moke by watching other gorillas and through the help of staff. Zookeepers helped trained Cayala, in part, by showing her pictures of mother gorillas and presenting her with toys to cuddle and kiss.“This infant’s arrival triggers many emotions—joy, excitement, relief—and pride that all of our perseverance in preparing Calaya for motherhood has paid off,” said animal keeper Melba Brown. “We will provide support to her if need be, but I have every confidence that Calaya will be a great mom to Moke. I am excited to see how he will fit into the group dynamic. There are a lot of different personalities in this family troop, but they all work well together.”Alex Hider is a writer for the E.W. Scripps National Desk. Follow him on Twitter @alexhider. 1581