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SAN DIEGO (KGTV) — In just days, Pfizer’s COVID-19 vaccine will go before a key group of scientific advisers to the Food and Drug Administration, and a San Diego doctor will be part of the process to cast an important vote.Dr. Mark Sawyer, an infectious disease specialist at Rady Children’s Hospital, will serve as a voting member of the Vaccines and Related Biological Products Advisory Committee or VRBPAC when the body meets Dec. 10 to publicly vet Pfizer’s COVID-19 candidate.Dr. Sawyer is also a professor of clinical pediatrics at UC San Diego. He has served before on this outside advisory committee to the FDA, but the stakes have never been so high.“I mean this is a tough decision,” he said in an interview Friday. “We're weighing the benefit of a vaccine against the risks. And with any new product, we don't know the risks and we have to estimate based on the data we have.”Dr. Sawyer said he received Pfizer’s full Phase 3 data Friday morning, making him one of the first Americans outside the FDA to see the full details of the company’s large-scale clinical trial. The FDA is expected to release the data to the general public by Tuesday, two days before the public meeting.Sawyer will be one of about 20 outside vaccine experts from around the country on VRBPAC. The FDA hasn’t yet released a full roster of the doctors and scientists who will take part. The independent advisory committee will hear comments from Pfizer and the FDA and listen to public input before voting on whether to recommend emergency authorization.The marathon meeting is expected to last up to nine hours.“The FDA counts on this advisory committee to be an independent group of people who are looking at the same information they looked at and asking us what our concerns are, or whether we reached the same conclusion that their staff have reached,” he said.The meeting comes on the heels of a study by Pew Research that found lingering skepticism of the vaccine. Just 60% of Americans planned to get vaccinated as of the survey released Monday.“I do think that's going to change once this committee meets and the data is made public and we can all talk together as a community about what we know about the safety, and what we don't know, frankly,” he said.Dr. Sawyer was a member of VRBPAC for four years and briefly served as the acting chair in 2017.The committee meets a few times each year to make recommendations on the annual flu vaccine and other drugs.The committee’s vote is not binding. The job of the outside advisers is to issue a recommendation and the FDA can overrule them, but the agency rarely does. From 2003 to 2019, VRBPAC made 105 recommendations. The agency fully implemented 84% of VRBPAC’s recommendations and partially implemented 10%, according to Union of Concerned Scientists.That means when the committee votes Thursday, it’ll carry a lot of weight. The FDA is expected to announce its final decision shortly after the vote, possibly within hours.Dr. Sawyer said the advisers will make a decision following the process they traditionally do, based on all the knowns and unknowns. “And we’re going to weigh that against what we're going through right now,” he said. “Our hospitals are getting overwhelmed. Our ICUs are getting full.”“We really need to do something to intervene and the vaccine is the best thing we've got going,” he added. 3369

SAN DIEGO (KGTV) - Marine Corps Air Station Miramar broke ground Friday on its first hangar to house the F-35, the most advanced fighter jet in the world.While the plane may be controversial, the hope is to replace aging aircraft. The new project will also include a flightline expansion."We're building new F-35 joint strike fighters and we're going to send them right here to Miramar,” President Trump said in his visit to the base Tuesday.Congressman Scott Peters and other military leaders were in attendance at the groundbreaking, thrilled about finally moving these projects forward."We're really taking care of the nation's defense," said Rep. Peters, representing the 52nd District. "One of the things when I went to the Armed Services Committee was to make sure that this facility was high on the list of priorities," he said. Harper Construction won the bid and will employ about 2000 workers.  The 160,000 square foot hangar is designed to hold up to 12 F-35s."We need to upgrade the infrastructure, the connections, the systems inside the hangers," said Col. Jason Woodworth, the Commanding Officer at MCAS Miramar.While critics have pointed to design flaws and skyrocketing costs on the new planes, the military says aging aircraft like the F/A-18 hornets are becoming tougher to maintain."Older airplanes are like that telephone on your wall you had when you were a kid with the rotary dial on it," Woodworth said. "[The] cell phone in your pocket, that's the F-35 that does it all.""3rd Marine Aircraft Wing was more excited than anybody here," said Asst. Wing Commander Michael Borgschulte with the 3rd Marine Aircraft Wing.The Marine Corps plans to replace its entire fleet of Harriers, Hornets, and Prowlers with new F-35s."The more flight hours, the more times our pilots can get in the aircraft an actually execute their mission, the more proficient they are," Borgschulte said.The Pentagon admits budget shortfalls have hurt military training, but it stopped short of blaming cutbacks for this week's F/A-18 crash in Florida that killed two navy pilots.The hangar should be done by January 2020, about the same time the F-35s are set to arrive. This groundbreaking kicks off just two of nine projects scheduled over the next 13 years.MCAS Miramar expects to have at least 70 F-35s by 2031. 2333

SAN DIEGO (KGTV) — Looking for dinner with a view?In San Diego, the best views are found up and down the county's coastline, according to OpenTable users. The dining website's rankings were pulled together 12 million reviews for more than 28,000 U.S. restaurants collected on OpenTable between June 2017 and May 2018.In San Diego, 10 restaurants took honors as one of the best places to grab something to eat that's just as beautiful as the scenery nearby: 479

SAN DIEGO (KGTV) — Mission Valley's Gordon Biersch restaurant may be closing, but the brewery location will live on under a new local eatery.Puesto will take over the location of the well-known restaurant after it closes in July, according to the company. The Mission Center Road spot will be the Mexican restaurant's third location.Gordon Biersch is set to leave Mission Valley on July 16, though no reason was immediately given for the closure, according to paperwork filed by the company. RELATED: Uber Eats to test drone delivery service in San DiegoPuesto will reopen the on-site brewery and try to retain as many of Gordon Biersch's staff as possible. The new restaurant plans to open in Fall 2019.The on-site brewery will give Puesto the opportunity to develop their own beer program, after collaborations with San Diego and Mexico breweries for years, in addition to its signature margaritas and cocktails.“The Puesto team has been doing cervecería collaborations for years now, working primarily with cervecerías in Mexico to create our own San Diego meets Mexico cervezas," Puesto co-owner Eric Adler said. "We’ve been looking for a space in San Diego for some time where we could develop our own cerveza program. This new space gives us the opportunity not only to brew, but continue bringing our innovative approach to authentic Mexican flavors to more of our hometown.”Puesto currently operates six restaurants around California, offering a variety of handmade tacos, bowls, and street food-style plates. 1525

SAN DIEGO (KGTV) - Libraries across San Diego County adapted quickly during the coronavirus pandemic, offering digital options for people to continue reading, researching, and connecting with the community."It's hugely important," says Migell Acosta, the San Diego County Library System Director. "People need libraries for serious study and recreational reading and then their information needs.""We knew that our main services were going to be reference, picking up library material and connecting to our technology," adds Ady Huertas, the Supervising Librarian of Youth and Family Services for the City of San Diego. "Luckily, during this time, we've been able to maintain that service, and we're really happy that we're able to do that."Moving to digital services when the pandemic forced branches to close took some adjustments but ultimately proved successful.Libraries moved money in their budgets from buying physical books to buying ebooks so people could have more options to download. The County library system went from 2 million ebook downloads in 2019 to 3 million in 2020 and amassed the state's 2nd most extensive digital library.The City Library created a virtual hub on Facebook to connect with people through storytime, videos, and more. It quickly grew to more than 2,000 followers."We went from creating some basic programming daily to having multiple programs per day for all ages," says Huertas. "We have a schedule. We have storytimes, book clubs, book talks, crafts, stem, learning opportunities, and we even have mindfulness programs and other folks we collaborate to create the content."Both systems also gave out nearly 30,000 take-home summer reading kits to keep kids excited about literacy.The County sent magazines and paperback books to members of the homeless population living in shelters and hotels.Libraries also expanded their online learning options. The County's high school diploma program for people aged 19 and up graduated 25 people during the pandemic and currently has 100 more enrolled.They also offered access to Linda.com, an online learning library of "how-to" videos."I love YouTube like everybody else," says Acosta. "But these are classes that are more business skills, how to do a presentation, accounting skills, and then deep level computer skills."They've had several thousand hours' worths of videos already viewed on the service since they added the service.In the spring, libraries were able to add in-person pick up of books. Over the summer, they offered limited access for people to come into the branches.They also made it easier for people to become library customers by offering library cards with only a phone number or email address.To help address the equity gap, libraries also allowed people to check out computers and other devices. They also expanded wifi signals at the branches to have internet access for people sitting outside the library.Library officials say the new emphasis on digital has made them better libraries in the long run."Whenever there's a challenge to be met, and you step up to the challenge, personally or as an institution, you become better for from that experience," says Huertas. 3187

来源：资阳报