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HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.
BRUSSELS, May 31 (Xinhua) -- Baby bottles containing the substance Bisphenol A (BPA) would have to be pulled from the shelves across the European Union (EU) starting from Wednesday, in a "milestone" move to better protect the health of EU citizens, an official said Tuesday."Due to the fact that there are uncertainties concerning the effect of the exposure of infants to Bisphenol A, the commission deemed it both necessary and appropriate to take action," said John Dalli, EU Health and Consumer Policy Commissioner."The aim is to further reduce the exposure of the most vulnerable part of our population, i.e. infants," he said.The ban, adopted in an EU directive in late January, would prohibit baby bottles containing BPA from placing on the EU market and import into the 27-member EU from June 1.Previously, the bloc had already banned the manufacture of the controversial baby bottles on March 1, and the industry has been withdrawing such products voluntarily.BPA is an organic molecule that is used in the manufacture of polycarbonate plastics, which are used to manufacture plastic materials, such as baby bottles.Traces of BPA can be released from plastic containers into the food they carry if these containers are heated at high temperatures. They may lead to early sexual development of children and could cause cancer, according to health officials.China would also prohibit the manufacture of feeding bottles containing BPA from June 1, while imports and sales of bottles containing BPA would be banned starting from Sept. 1.
BEIJING, Aug. 24 (Xinhuanet) -- Married patients are more likely than single ones to survive 15 years after heart surgery, according to a study online in the Health Psychology.Researchers of the study tracked 225 people who underwent coronary bypass surgery from 1987 to 1990. They found that 124 patients of them, or about 55 percent, survived for at least the next 15 years. And 61 percent of the married patients and 30 percent of the unmarried survived.Kathleen King, lead author of study, said that the close connection to another person in a marriage lengthened patients’ lives."Marriage gives you purpose in life, and feeling like you have a reason to live is an important part of doing the things you need to do to stay alive," Harry T. Reis, co-author of the study, said. "Married people also help each other; remind each other it's time to take their pills. And they probably eat healthier."However, the marriage quality had different effects on the survival odds between men and women. Men who had bypass surgery lived longer by virtue of simply being married, regardless of how happy or miserable the union, but the marriage quality had more impact on women's survival after surgery. 83 percent of the happily married women had survived, compared with 28 percent of the less happily married women and 27 percent of the single women. Among the men, 83 percent of the happily married were still alive, compared with 60 percent of the less happily married and 36 percent of the single."The most dramatic thing to me is [that] just being married, especially if you had a happy marriage, had that big an effect 15 years later," King told ABCNews.com.Marriage does not only have a positive effect on the survival of patients after heart surgery, but also benefits patients with other diseases.In recent years, a number of studies have showed several apparent health benefits of marriage. For instance, it might slightly add the odds of survival from colon cancer and help reduce pain in rheumatoid arthritis patients.
HOUSTON, July 25 (Xinhua) -- A shelter-in-place was ordered after a battery caught fire during a testing at NASA's Johnson Space Center Monday morning.A battery was being tested inside a containment system when it got overheated and caught fire at about 9 a.m. local time, ABC quoted the Houston Fire Department (HFD) sources as reporting.A shelter-in-place was issued for a few buildings because it's believed that one of the bi-products of the combustion could be dangerous, HFD said.The fire was put out before 11:30 a.m.A firefighter was injured when a hydrant cap blew off and struck him, according to ABC.
BEIJING, July 26 (Xinhuanet) -- Seven of the 20 top selling American prescription drugs will lose their patents by the end of next year, making way for less expensive generic versions, according to media reports.It's a shift that could save consumers billions of dollars -- assuming those big-ticket medications are willing to give up a trusted brand name for an off-label replacement.The prices of medications such as cholesterol-fighting Lipitor and blood thinner Plavix are expected to go down significantly, according to the U.S. Food and Drug Administration (FDA).Lipitor will lose its patent in November. When that patent expires, people are advised to buy atorvastatin, the generic equivalent. Other brand names include the anti-psychotic Zyprexa and the rheumatoid arthritis and psoriasis drug Enbrel, of which the patent will expire in October and October of next year, respectively.Over the next 10 years, an estimated 120 more brand-name prescription drugs will lose their patents in the U.S.