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Tinder's parent company Match Group is suing competitor Bumble, accusing the female-friendly dating app of patent infringement and stealing trade secrets.The lawsuit, filed Friday in Texas, says Bumble is virtually identical to Tinder, the app that popularized the swipe right to like, swipe left to dislike functionality.Bumble copied the "world-changing, card swipe-based, mutual opt-in premise" of Tinder, the lawsuit says.The complaint also says that Bumble's co-creators are ex-Tinder employees, and the app has rolled out two new features that were "learned of and developed confidentially while at Tinder."Bumble has become a fierce competitor to Tinder since it launched in 2014. Bumble's differentiating factor is that only women can make the first move. But Match confirmed last month it plans to launch that feature in its own app.In the complaint, Match says it "applauds Bumble's efforts at empowering women, both in its app and offline" and "cares deeply both about its women users and about women's issues generally.""This case is simply about forcing Bumble to stop competing with Match and Tinder using Match's own inventions, patented designs, trademarks, and trade secrets," it says.The lawsuit is the first time that Match Group, which also owns dating sites Plenty of Fish and Match.com, has enforced the patents it secured on swiping and double opt-ins for dating matches on Tinder, according to a company spokesperson.Tinder and Bumble have had a complicated history.Bumble was launched by Whitney Wolfe Herd, an early employee at Tinder.Wolfe Herd left Tinder in 2014 after alleging sexual harassment and discrimination. The case was eventually settled. Ex-Tinder employees Chris Gulczynski and Sarah Mick joined Herd to start Bumble more than three years ago. Gulczynski and Mick, who are designers, are at the center of the stolen secret allegations in the suit.The two had knowledge of an "undo" button talked about at Tinder, according to the complaint. That feature was "nearly, if not literally, identical" to Bumble's backtrack feature, the lawsuit says. The backtrack feature allows users to go back in time to "like" someone they may have accidentally passed on.Gulczynski and Mick also helped implement photo messaging at Bumble, something Gulczynski had allegedly mocked up a design for while at Tinder.In a statement, a Match Group spokesperson said the company is "committed to protecting the intellectual property and proprietary data that defines our business,"Bumble did not immediately respond to request for comment. According to the Linkedin accounts for Gulczynski and Mick, both have left Bumble. They did not immediately respond to messages seeking comment about the lawsuit.Axios was first to report that Match Group had filed the suit.It's been widely reported that Bumble once turned down a buyout offer from Match Group. Match Group was reportedly still interested in Bumble's business as recently as November of last year.Match Group said it doesn't comment on mergers and acquisitions speculation.In an interview with journalist Gayle King at the SXSW festival last week, Wolfe Herd declined to talk about any conversations — past or present — with Match Group, the parent company of Tinder. 3251

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

Top senators eager to target Saudi Arabia over the murder of journalist Jamal Khashoggi?plan to meet Thursday to try to cut a bipartisan deal curtailing US involvement in the war in Yemen, suspend arms sales with the Saudi kingdom and rebuke the crown prince, Mohammed bin Salman.The goal of the senators is to reach bipartisan consensus on a deal that could be on the floor as soon as Monday, according to members involved in the effort."There's a consensus among a lot of us that we want to suspend arms sales and stop support for the war -- how do you best do that?" said Sen. Lindsey Graham, a South Carolina Republican who is directly involved in the effort.Asked if he's spoken to the White House about the push, Graham said bluntly: "They know where I'm at.""It'll have teeth," said Senate Foreign Relations Committee Chairman Bob Corker, a Tennessee Republican, who added that the senators are trying to piece together various proposals into one plan to achieve bipartisan consensus. "We're trying to get everything together so we do something constructive."The move would amount to a rebuke not just to Saudi Arabia -- but also to Trump, who has downplayed the murder of Khashoggi and cast doubt on the crown prince's role?in the murder while also promoting economic ties of the US and Saudi Arabia. Among the ideas: Formally halt arms sales between the kingdom and the US, a top Trump priority, while also limiting the US involvement in the Saudi-led war in Yemen, which the Trump administration supports. Moreover, senators are debating how best to target the crown prince, whether it's through a non-binding resolution blaming him for the murder or seeking to slap him with sanctions."Honestly, left to my own accord, I would focus on (bin Salman)," said Corker, who is retiring at the end of his term in January, but added that any deal would also weigh in on the US involvement in Yemen.Corker also said CIA director Gina Haspel gave the "most precise presentation I've ever heard in 12 years" in the Senate when she briefed senators Tuesday on the Khashoggi murder.He said that a colleague corrected his comments Tuesday that a jury would convict bin Salman in 30 minutes. It would have been "20 minutes," he said the colleague told him.Corker said he would be "benevolent" and give Defense Secretary James Mattis and Secretary of State Mike Pompeo the benefit of the doubt for their prior briefing, saying they may be downplaying a link with the crown prince because they haven't seen the same intelligence that the CIA director has.Without a bipartisan deal, Corker warned that a measure -- drafted by Sens. Bernie Sanders of Vermont, Mike Lee of Utah and Chris Murphy of Connecticut -- to end US support within 30 days for the war in Yemen would pass the Senate as soon as next week."If there's not (a deal), the other one looks to me like it's going to get 51 votes," he said.But with only limited time left in the lame-duck session, GOP leaders are wary about bringing up the measure because it could dominate the floor schedule next week. Because of the unusual process, bringing up the Sanders-Lee-Murphy measure -- without a bipartisan deal to consider amendments -- could open up the floor to a session known as a "vote-a-rama" that could open up the bill to a wide-range of unrelated issues."The conundrum is if we get on it without an agreement on amendments then we've got a vote-a-rama," said Senate Majority Whip John Cornyn, a Texas Republican. "And so there's no germaneness requirement, so everything from criminal justice reform to repeal-and-replace Obamacare to Medicare-for-all are all fair game. That's the conundrum."Cornyn added: "I think we should condemn the murder of Khashoggi in the most emphatic terms but I don't think we should cut our nose off to spite our face with regard to the proxy war in Yemen against Iran." 3885

This Labor Day, gas prices are set to be the lowest since 2004.According to AAA, the national average is .23, which is down 34 cents from last year.Gas Buddy reported the national average for the lowest-priced gas price on Labor Day was .82 per gallon in 2004.AAA said car trips are down 3% from last year, with air travel being down 75%."That means that motorists should expect heightened traffic throughout the Labor Day holiday, on top of new restrictions and precautions necessitated by the current health challenge," AAA said in a press release.AAA says prices at the pump will continue to drop in the coming weeks, as "demand falls and refineries in the Gulf of Mexico region come back online in the wake of Hurricane Laura." 743

They call it "The Game." But one of the fiercest rivalry college football games will have to wait a few more weeks due to the massive Camp Fire burning in Northern California. Due to the poor air quality in the Bay Area from the Camp Fire, Saturday's Stanford/California football game has been postponed until Dec. 1. The game will take place one day after the Pac 12 championship game, but both teams have already been eliminated from contention. As of Friday, the Camp Fire has killed at least 63, and hundreds are missing. The game, which was going to be held on California's Berkley campus, is just one of many college sporting events being postponed this weekend due to poor air quality. "We have been carefully tracking air quality in Berkeley and the Bay Area over the past week, relying on the best data and guidance available to us from medical and environmental experts," California's Athletic Director Knowlton said. "The forecasts we have received show a minimal chance of the improvement necessary to hold the game on Saturday. While we would have preferred to play the Big Game on its scheduled date, once we realized that air quality would likely not return to acceptable levels, we made the decision to postpone for the health and safety of our student-athletes, coaches, gameday staff, students, band and spirit groups, alumni and fans."Berkley is located roughly 150 miles from Paradise, which was the epicenter of the Camp Fire.  1481

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