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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394

For companies hiring right now, ensuring you're hiring the most qualified candidate can be tricky. The COVID-19 pandemic has changed the way businesses approach hiring and are forcing them to recruit remotely. "Everything we’ve always done previously has been in person. It’s always been encouraged to do in-person, face-to-face communication. From a job seeker's perspective, obviously, it helps to be in-person and kind of take their facial cues and whatnot, so we really had to change everything we were doing," says Erik Cherkaski with the Fresno Regional Workforce Development Board. Cherkaski says one of his main jobs is to recruit employees for local businesses. Because of the pandemic, their recruiting services are now virtual. Recently, the organization has been holding virtual job fairs for a number of large employers."I think one day we had logistics, so we had some of our local fulfillment centers on. Another day we had the service industry on, so some of the local retailers that were doing mass hiring [participated]. Then, we had a focus on government, as well. So, some of the local and state organizations that were doing some hiring and we had some very good turnout. This was new territory for us," said Cherkaski.Employers held virtual presentations for candidates who tuned in using online meeting platforms like Zoom and Webex. "It was very engaging. We got good feedback from our employers and we are looking to do it again. So that was very positive for us to see that we can do something like this online," said Cherkaski.College students and recent graduates are also finding their first career move by participating in online events. Handshake, which helps connect more than 500,000 employers with college students looking for a job or internship, says it's expanding it's virtual services to accommodate universities who've put their in-person career fairs on hold."There are a lot of opportunities that do still exist even with the change in the economy this particular year. We have so many students across so many different walks of life that are looking in for those opportunities to be able to just jump start their career," said Christine Cruzvergara, with Handshake. To help, Handshake created a new virtual engagement module."That is going to allow employers to be able to actually segment, campaign and reach out to candidates that meet the different criteria and qualifications that they are looking for, across all of our thousands of universities and colleges. They can go beyond the basic qualifications in a virtual fair to be even more tailored around, for example, some of their DEI requirements or their goals," said Cruzvergara.Handshake hopes the new tools not only help employers narrow down the types of students they want to hire, but also helps students. "It's going to allow students to maximize the time they do have in between classes or in-between their part time jobs or things they might be doing other responsibilities or obligations they have," said Cruzvergara.As for how long Fresno Regional Workforce Development Board will be holding their recruiting events virtually, Cherkaski said, "if you were to have asked me this four months ago I would have said, Oh this isn’t going to go on too long but now we're four months in and I suspect were going to be doing this for the foreseeable future."Both Fresno Regional Workforce Development Board and Handshake believe even when COVID-19 restrictions are lifted completely, employers will still want to use virtual recruiting events to widen their candidate search.Editor's note: An earlier version of this story incorrectly identified Christine Cruzvergara's last name. 3693

For two minutes, people and traffic in Israel today paused to remember the estimated 6 million lives lost during the Holocaust.The Times of Israel reports that at 10 a.m. local time, nationwide sirens blared as a day of remembrance began. It also shared this video to Facebook: The Holocaust was a genocide during World War II in which millions of European Jews were killed by Nazi Germany led by Adolf Hitler, between 1941 and 1945.Beginning in the early 1930s, the German government passed laws to exclude Jews from civil society. Many were moved to concentration camps, ghettos and detention sites.A new survey found that Americans are beginning to lack basic knowledge about the Holocaust.The survey found that nearly half of all Americans — 41 percent — couldn't identify Auschwitz, a concentration camp where an estimated 1.1 million Jews and minorities were killed at the hands of Nazis during World War II. Among millennials, that number rose to 66 percent.The survey also found that a significant portion of Americans don't understand the scale of the Holocaust. Go here to read more on the results of this survey. 1166

ly injury to a public safety officer, authorities said, citing a criminal complaint, which is sealed. 1307

FREDERICK, Colo. -- A Frederick husband and father is behind bars in the Weld County Jail, booked early Thursday morning for the disappearance of his pregnant wife and two young daughters.According to two law enforcement officials, Christopher Watts, 33, has confessed to killing Shanann?Watts, 34, and their two daughters — 3-year-old Celeste and 4-year-old Bella. Officials believe they know where the bodies are.Watts and her daughters were reported missing out of Frederick on Monday. The Colorado Bureau of Investigation issued a missing-endangered alert for the three on Tuesday. A day later, the Federal Bureau of Investigation joined in the search.Just after midnight Thursday, an official with the Frederick Police Department said they had made an arrest "in connection to the missing person's case" involving Shanann Watts and her two girls. Officials said they were awaiting charges for the suspect, who will be held at the Weld County Jail for the time being.Police declined to comment further on the investigation. Watts was 15 weeks pregnant. In an interview with Scripps station KMGH in Denver on Tuesday, Chris Watts said his wife’s purse, keys and phone were all left at home before she went missing. You can watch the full interview below: Town of Frederick officials said they would provide another update in this case on Thursday at 10:30 a.m.  1422