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The Wake Forest Institute for Regenerative Medicine says it has a new use for its bioprinting system. In the past they've 3D printed normal-size organs and tissues in hopes of someday implanting them in patients.For the coronavirus, the lab is creating organs using human cells that can be as small as a pinhead. They're focusing on the organs most likely to be infected by the disease. like the lungs.“And so we've been playing with a number of agents to, on both prongs what can make it more infective, what can make it less infective to try to sort this out for the future,” Anthony Atala, director for the institute said.Atala says he hopes the system will help in testing drugs before they hit the market.Drug companies do extensive testing and clinical trials in people before releasing a new medication.Atala says sometimes those companies find no serious side effects, but then years later, discover that it's toxic to patients taking it. Atala says testing a drug using the bioprinting system can tell if a drug is toxic in weeks instead of after years on the market.“Even though we've used the tool extensively for toxicity testing, it's also a tool that can be used for screening,” Atala said. “So we can test agents that are currently being considered for testing against COVID and test the efficacy of the treatment on miniature human organs made up of normal cells”To be clear, Atala said drug tests on 3D printer organs are not meant to replace clinical trials in humans, be are an added step to better predict what will happen in those trials. 1567

The Trump administration has finalized a regulation that overturns Obama-era protections for transgender people against sex discrimination in health care. Friday's action is certain to be challenged in court by LGBTQ groups and others.The policy shift, long-sought by the president’s religious and socially conservative supporters, defines gender as a person’s biological sex. The Obama regulation defined gender as a person’s internal sense of being male, female, neither, or a combination.The Trump administration said that the new rules come with a .9 billion budget reduction over the course of five years. The costs are associated with enforcement efforts. “HHS respects the dignity of every human being, and as we have shown in our response to the pandemic, we vigorously protect and enforce the civil rights of all to the fullest extent permitted by our laws as passed by Congress. We are unwavering in our commitment to enforcing civil rights in healthcare,” Roger Severino, Director of the Office for Civil Rights at HHS.The Human Rights Campaign already announced it will sue the Trump Administration to stop the move.“We cannot and will not allow Donald Trump to continue attacking us. Today, the Human Rights Campaign is announcing plans to sue the Trump administration for exceeding their legal authority and attempting to remove basic health care protections from vulnerable communities including LGBTQ people. And, to add insult to injury, the administration finalized this rule on the anniversary of the Pulse shooting, where a gunman killed 49 people in an LGBTQ nightclub,” said HRC President Alphonso David. “LGBTQ people get sick. LGBTQ people need health care. LGBTQ people should not live in fear that they cannot get the care they need simply because of who they are. It is clear that this administration does not believe that LGBTQ people, or other marginalized communities, deserve equality under the law. 1940

The U.S. has now surpassed 17 million confirmed cases of COVID-19 and has yet again recorded more than 1 million cases of the virus in less than a week, according to a database kept by Johns Hopkins University.The U.S. reached the 16 million case threshold over the weekend. According to the COVID Tracking Project, the country is averaging more than 200,000 new cases of the virus every day, putting it on pace to record 1 million cases every five days.Since Oct. 30, the U.S. has recorded more than 8 million cases of COVID-19 — a number that represents 47% of all cases recorded since the virus reached the U.S. in January. The U.S. is currently in the midst of the most deadly stretch of the pandemic to date. The country surpassed 300,000 deaths linked to the virus on Monday. Since then, nearly 8,000 more people have died of the disease.The COVID Tracking Project reports that the U.S. has averaged more than 2,500 deaths every for the last week — and that number will likely increase in the weeks to come. The COVID Tracking Project also reports that record numbers of Americans are battling the virus in a hospital. The group says more than 113,000 people are currently hospitalized with the virus, leading many health care facilities — particularly those in rural areas — to reach maximum capacity levels.Spikes in COVID-19 typically trail behind spikes in cases and hospitalizations, meaning death totals will likely only increase in the weeks to come. 1481

The risk of homelessness looms large for many across the country as people deal with job loss and economic uncertainty brought on by the coronavirus pandemic.The National Alliance to End Homelessness estimates, right now, there are 567,000 people who call the streets their home, a number that has only risen since March.There are shelters, soup kitchens, and myriad charities to help, but the group Foundations for Social Change, a charitable organization based in Vancouver, Canada, suggests one source of help trumps the rest: money.“Sometimes a little bit of a hand up can mean all the difference in whether or not someone is going to stabilize and get into housing or not,” said chief public policy officer for the Colorado Coalition for the Homeless Cathy Alderman.It might seem like an obvious solution, but it is challenged by the preconceived notion that people battling homelessness might squander the money or spend it on harmful habits like alcohol, drugs, or cigarettes.“I think it’s not surprising at all that people who are struggling with the cost of living and forced to sleep outside would use dollars given to them to get inside into a home,” said Alderman.In September, Foundations for Social Change wrapped up nearly two years of research that suggests those in less fortunate circumstances would use money to help secure food and housing, rather than illicit substances.Back in 2018, the group gave 50 people battling homelessness in Vancouver a lump sum of ,700, without restriction, to see what they would spend it on, and they compared the findings to a group of 60 homeless individuals who were not given any lump sum.Foundations for Social Change found that in the first month, the group that received the payment, 70 percent of them were able to access a sustainable food source that they maintained for the rest of the year. They also found stable housing at a rate that outpaced those who had not received the payments by 12 months.The researchers also found that spending on items like drugs, alcohol, and cigarettes decreased by 39 percent.“The key findings were phenomenal and were even well beyond my expectations,” said one of the head researchers, Dr. Jiaying Zhao. “This actually is counter to our common assumptions of how these folks will spend their money and cash, so that was very good to see.”“I would save a third, spend a third on things I know I needed, and then give a third away,” said Benjamin Dunning, who was homeless for nearly five years following the Great Recession in 2008. “There just wasn’t any work available and I was like, 'well, better dig in for the long haul.'"Dunning says following an injury that prevented him from working he was no longer able to afford rent in the Denver suburb where he lived. He says he moved from shelter to shelter, trying to weather the storm before he was able to find a community of other people in a similar situation that offered a little more stability and a consistent roof over his head.“One thing I found out is [the homeless people I was around] were just like my neighbors in the suburbs,” said Dunning. “Most of them were people who had gotten stuck on hard times and trying to figure out how to deal with it.”The study by Foundations for Social Change focused on people who had been homeless for a year or less and who had been screened for a low risk of mental health challenges and substance abuse. So, Dr. Zhao says this is not a silver bullet, but an encouraging sign to help solve an issue that has several layers of complexity. 3546

The U.S. surpassed 200,000 deaths linked to COVID-19 on Tuesday, according to a database kept by Johns Hopkins University.The deaths — all of which have occurred since February — out-total the number of Americans lost to World War I, the Korean War, the Vietnam War, the War in Afghanistan and the Iraq War combined.The 200,000 deaths are the most of any country around the world. Brazil currently ranks behind the U.S., with about 137,000 deaths.According to Johns Hopkins the U.S. also has among the highest COVID-19 mortality rates in the world. About 61 Americans per 100,000 have died of COVID-19. That ranks sixth in the world and in the company of countries like Spain (65.27) and Mexico (58.24)The U.S. also leads the world with 6.8 million confirmed cases of COVID-19. India (5.5 million), Brazil (4.5 million) and Russia (1.1 million) are the only other countries with at least 1 million confirmed cases of the virus.Johns Hopkins reports that daily confirmed cases of COVID-19 dropped throughout the month of August. However, case rates have ticked up throughout September, and top health experts like Dr. Anthony Fauci are bracing for a difficult winter.Earlier this month, Fauci warned that a wintertime surge could be possible as weather forces Americans indoors and cities begin relaxing COVID-19 lockdown restrictions. Health officials have warned that large indoor gatherings can result in COVID-19 superspreader events.The Institute for Health Metrics and Evaluation at the University of Washington — a model often used by the White House — currently projects that an additional 175,000 Americans will die of the virus by Jan. 1. That projection could drop to as little as 65,000 additional deaths with a universal mask mandate and could increase to as many as 225,000 additional deaths with easing restrictions. 1838