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SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648

SAN DIEGO (KGTV) -- It has been nearly two years since Denelle Mitchell’s husband took his own life. CAL FIRE Captain Ryan Mitchell died by suicide on November 5, 2017, at the Interstate 8 Pine Valley bridge. Denelle Mitchell did not want to talk about the day it happened, but the emotions she dealt with in the days and months after his death are hard to forget. “One of the first feelings I felt was ashamed or embarrassed at the type of way that he died,” Denelle Mitchell said. “It comes and goes in waves of being mad or sad.”Her husband was dedicated to his job — a job that was his passion.“He loved the acts of fighting fires. He loved the community… the brotherhood and sisterhood that they had,” Denelle said. But there were difficult days. “What comes with that is a lot of hard work, a lot of hours away from your home and your family and your friends.” What wasn’t obvious to many were struggles behind the scenes.RELATED: Veterinarian suicides on the rise: Student loan debt, compassion fatigue among factors in suicide increase“He did talk about his depression quite a bit and I lived it with him. I was there with him when we were going through some really hard times,” Denelle said. “Marriage can be hard, owning a home and renovating a home can be hard, having a kid — that’s a lot of life stresses.”There were also tough times at work. “The fire seasons were getting longer and harder,” she said. “There’s days where as a firefighter wife, they come home and they just are so exhausted — mentally, physically, and emotionally drained." The Firefighter Behavioral Health Alliance recorded 98 firefighter and EMT suicides so far this year. Jeff Dill, the founder of FBHA, said the number this year is on track to be higher than 2018. In 2018, there were 108 suicides. In 2017, the number was 120. A study by the Ruderman Family Foundation said depression among firefighters is nearly double the general population. Firefighters and police are at higher risk for depression, post-traumatic stress disorder, and suicide, according to the study.Denelle now focuses on raising their son, Aiden. She encourages loved ones to pay attention to those who may be struggling. “Don’t just let it go by the wayside. Don’t take no for an answer… try to research the signs,”Denelle said.Locally and statewide, action has been taken to ensure resources are available for first responders. Recently, the County Board of Supervisors approved the Captain Ryan J. Mitchell First Responder Behavioral Health Program, which will offer confidential mental and behavior health support by connecting first responders with a clinical professional.The governor also signed several bills that focus on improving protections for the state’s firefighters and first responders when it comes to mental health. AB 1116 (the California Firefighter Peer Support and Crisis Referral Services Act) establishes statewide standards for peer support programs. SB 542 (the Trauma Treatment Act) will provide “first responders with workers’ compensation while they recover from their mental health scars,” according to a news release from the governor’s office. “Bringing awareness to the topic makes it easier to talk about,” Denelle said. She said she is grateful that she did not have to go through this process alone. “I wanted to thank all our friends and family for the support, especially the Cal Fire community, Local 2881, and Chief Patrick Walker,” Denelle told Team 10. She is now raising money for suicide prevention awareness, This Saturday, she will be participating in the Out of the Darkness San Diego Walk, supporting the American Foundation for Suicide Prevention.To donate to her cause, click here.If you or anyone you know needs help, the crisis number is 888-724-7240. 3775

SAN DIEGO (KGTV) -- It will take about a month to get the old Family Courthouse in downtown San Diego demolished and the area cleaned up, and once it’s gone, work will begin on what will replace it -- brand new affordable housing units.Piece by piece, the building that once heard divorce, custody, and other domestic issues was torn down. In its place will be a new eight-story building with 120 affordable housing units at the corner of Sixth Avenue and Cedar Street.While it’s been vacant, it was used as a temporary shelter for migrant families seeking asylum. Soon it will become home to senior citizens and other families.To be eligible for this affordable housing, a household must make less than 60% of the area median Income. For San Diego, according to the San Diego County website, it is less than ,000 for one person.County Supervisor Nathan Fletcher said the location plays a big part in this project.“Everyone one wants affordable housing as long as it's not near them, but we know this is where housing needs to go. This location is in an urban environment in a downtown setting along transit corridors, walking distance to services is where we need to go,” Fletcher said.After the building is demolished, the next step in this project will be to get community input on the design of the unit. They don’t expect to break ground until 2024. 1365

SAN DIEGO (KGTV) — It's not the most family-friendly event in town, but it is one of San Diego's most time-honored bashes.The 66th Over-The-Line (OTL) World Championship returns to Fiesta Island Park for two weekends July 13 and 14, and July 20 and 21. The annual event, known for its color team names and characters, started locally in the 1950s and has since become a highlight of summertime in San Diego.What more can you ask for during the sweltering heat? Sunshine, brews, and a simple sport that everyone can follow. Well, it may not be that simple for newbies, but it's a quick lesson.RELATED: Ocean Beach summer tradition returns as 'David Buoy' is deployedHere's what to know:The batter and pitcher are on the same team. The batter's goal is to hit the ball into fair territory (over the line) without a fielder catching it. A hit includes any ball that lands in fair territory, if a fielder crosses over the line, or if a fielder drops the ball in fair or foul territory.If a batter connects with the ball but it does not cross the line, it can be saved and ruled a "no pitch" if the batter or pitcher are able to catch the ball before it hits the ground. Kind of like a redo pitch.An out is recorded when the ball fails to cross the line, a batter swings and misses, a fielder catches the ball in fair territory, a batter has two fouls, a player bats out of order, or if a pitcher or batter touch but do not catch a ball that falls short of the line.Nobody actually runs bases — at times, that's probably for the best — and three outs end each half of an inning just like baseball.To score:The third hit of a half-inning scores one run and each hit after that scores another run.A home run, which is when a ball lands past the last fielder without it being touched, scores a run and any hits before it. The hit count is then reset to zero.Anyone is free to spectate, but the Old Mission Beach Athletic Club (OMBAC) has a few guidelines. Participants and fans follow the "No Bs" of OTL, which include no bottles, no bowzers (dogs), no babies, and no battles (fighting.) RELATED: San Diego Airbnb experience transforms clients into mermaidsWhile the event is free, organizers warn that OTL is not the most appropriate and safe event for children due to crowds, language, booze, and the open sports setting.Before heading out, check traffic and weather conditions around the Mission Bay area. For more information on team registration, tickets, and parking visit the OMBAC website. 2497

SAN DIEGO (KGTV) -- Just beyond the gates to Richard J. Donovan Correction Facility are rows of chain-linked fence topped with razor wire.Guard towers surround the complex southeast of San Diego; signs display a warning of no trespassing.The elaborate security set-up is designed to keep inmates in, but those serving time have discovered they don't need to be beyond the walls to inflict havoc on the world outside.Inmates are using cell phones and social media accounts to try and pimp women on the outside."They will work these girls and women outside of prison," said San Diego County Deputy District Attorney Carolyn Matzger. For the past six years, she's been in the sex crimes and human trafficking division.Pimping from prison is a phrase Matzger's become all too familiar with.Team 10 investigator Adam Racusin asked Matzger if pimping from prison is a growing trend."It's something that we definitely realized is happening," she said.Matzger authored an article in "Law Enforcement Quarterly" profiling the first prison trafficking case the San Diego Human Trafficking Taskforce handled.According to the article, a detective in Arizona saw a social media profile with pictures of a man in prison clothes. "The detective, using an undercover social media account of a fake 18-year-old woman, sent a message to the inmate Wendell Bullock." "So he was serving a rape sentence and trying to work women while he was in prison," Matzger said.Court paperwork obtained by 10News shows Bullock identified himself as a pimp during the communication with the detectives. He asked if they had escorted before and told them they could make money together. Bullock made statements that the female's job was to make money and Bullock would be responsible for posting the ads and for keeping her safe.According to the documents, Bullock would tell the girls what to say on the phone and what to look out for. Bullock told one of the females that she would not be having sex for less than 0."It's the promises they make of, 'Hey this is a quick buck. You could make good money doing this. I believe in you,'" Matzger said. "They often say to these women, 'I believe in you.'"This scheme ended with Bullock pleading guilty. He got an additional 10 years behind bars for pandering.In his plea agreement, Bullock wrote that he unlawfully encouraged the undercover detective to become a prostitute by using promises or device or scheme."If you have a human being and you are able to sell that person over and over and over again, that's very very lucrative," Matzger said.A state corrections official told 10News "contraband cell phone usage is a problem that CDCR takes very seriously.""Cellphone use by inmates can pose a security risk. Modern cell phones can record video and audio, and connect to the Internet. Additionally, contraband cellphones in state prisons can be used to facilitate or commit crimes, including illicit gang activity," said Vicky Waters, CDCR Press Secratary."The department has implemented many strategies to curb introduction and use of contraband cellphones, including the Managed Access System (MAS) or jamming/interruption technology, K-9s trained to detect cellphones, the use of parcel scanners, low-dose full-body scanners, metal detectors, etc., which provide a good foundation for preventing contraband from entering the institutions. Also, under CDCR regulations, inmates are prohibited from internet access. Thus, this implicitly bars inmates from access to social media since internet access is required in order to access such social media. Given the prohibition on internet access and also the fact that inmates are barred from possessing cellphones or wireless communication devices, the manner in which California inmates access social media is in violation of the law," said Waters.In the San Diego County region, sex trafficking is an 0 million business annually.Traffickers can make anywhere from half a million dollars on up.The average age of someone who's recruited is 16-years-old.Matgzer says kids are recruited from every neighborhood in the county. As for what motivates the pimps, Matzger won't speculate. In prison, inmates have a lot of time and are looking for ways to make money, says Matzger.Despite being behind bars, inmates can still have a lot of influential power inside and outside the correctional facility."They can do these blasts really quick for them to reach a lot of people and they only need one or two people to bite, and then they've got a business," Matzger said. Since Bullock's case, the human trafficking task force investigated four inmates in three other state prisons who are suspected of using cell phones to traffic.Two of those inmates have already been brought to San Diego County to be prosecuted.If you're a victim or know someone, there's help out there. Call the National Human Trafficking Hotline toll-free hotline at 1-888-373-7888. Anti-Trafficking Hotline advocates are available 24/7 to take reports of potential human trafficking. Text the National Human Trafficking Hotline at 233733. Chat the National Human Trafficking Hotline at www.humantraffickinghotline.org/chat. 5178

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