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Immunotherapy has gained ground against a stubborn opponent: ovarian cancer. A personalized cancer vaccine is safe and may lengthen the lives of ovarian cancer patients, a small clinical trial found.The research, published Wednesday in the journal Science Translational Medicine, showed "significantly higher" overall survival at two years among patients who received the vaccine, compared with patients who did not.Ovarian cancer is a "silent killer" because often it goes unnoticed until it is diagnosed at a late stage. Treated with surgery followed by chemotherapy, most patients -- 85% -- relapse and ultimately develop resistance to the chemo. At this point, they run out of treatment options.Still, scientists are hopeful based on the fact that a subset of patients shows an immune response to their cancer. Generally, these patients have better survival rates than those whose immune systems don't react in the same way.A vaccine, then, might be able to trigger and boost the immune system and increase the survival rates of patients, said Dr. Lana Kandalaft, senior author of the new study and an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine.  1210

In an interview this week, Donald Trump Jr. said he is waiting for “due process” in the case against a teenager accused of shooting three demonstrators in Kenosha, Wisconsin, killing two, and seemed to refer to being at the protests and the shootings as “stupid things.”The president’s son was talking to ExtraTV about his book, “Liberal Privilege: Joe Biden and the Democrats Defense of the Indefensible.”The show’s host, Rachel Lindsay, asked Trump about the Black Lives Matter movement, as racial tensions and violence at some demonstrations are brought up at President Trump and Former Vice President Joe Biden’s campaign events.After initial questions about what Trump Jr. thought of the movement, Lindsay asked, “The phrase 'Black Lives Matter…' do you understand what that means and what the fight is for it?"“Of course. And I agree with it,” Trump Jr. said, “It’s a very good marketing message, it's a great catchphrase, but that doesn't back up a lot of the political ideology behind it.”Lindsay then asks about his reaction to events in Kenosha. Jacob Blake, 29, was shot several times in the back by a Kenosha police officer. He is recovering in the hospital after his spinal cord was severed.Video of the shooting went viral and sparked demonstrations for several nights in Kenosha. It also inspired professional athletes to cancel practices and games the week of the shooting, to urge their leagues and fans to think about social injustice issues. A few nights after Blake’s shooting, investigators say 17-year-old Kyle Rittenhouse drove to Kenosha from his home in Illinois with an AR-15. He allegedly shot three demonstrators, two of them died.Rittenhouse was arrested at his home and faces five criminal counts including intentional homicide and reckless homicide.On a visit to Kenosha, President Trump visited with police officers and business owners whose stores had been damaged by protesters. He said he did not meet with the Blake family because they wanted a lawyer present for the meeting.Lindsay pressed Trump Jr. on why the administration has not spoken out about what happened to Blake, or the demonstrators who were shot."But why hasn't the Trump Administration or President Trump condemned what happened in Kenosha with Kyle Rittenhouse… coming across state lines and… murdering two people and injuring another [at a protest]?” Lindsay asked.“We're waiting for due process. We're not jumping to a conclusion… If I put myself in Kyle Rittenhouse['s shoes], maybe I shouldn't have been there. He's a young kid. I don't want young kids running around the streets with AR-15s… Maybe I wouldn't have put myself in that situation — who knows...? We all do stupid things at 17,” Trump Jr. replied.“It's a little beyond stupid," Lindsay responded.“Really stupid — fine. But we all have to let due process play out and let due process take its course,” Trump Jr. said. 2895

IMPERIAL BEACH, Calif., (KGTV) — One week after San Diego County lifted the beach closure at the Imperial Beach Pier, many people are enjoying the waves. But parts of the coastline remain closed due to the Tijuana River runoff contamination. Nicolas Pasculli of Hillcrest, drove down specifically to Imperial Beach to avoid the weekend crowds.“We’ve had rain for such a long time. It’s nice to enjoy the sunshine and the fresh air," Pasculli said. We met him sunbathing on the sand, just south of Seacoast Drive. Compared to some of the other areas in the county, this beach was empty.“Maybe because the sign is up and it says to be careful, the water might be contaminated,” Pasculli said. Bright yellow signs are clearly posted at the entrance of the beach. Last week, San Diego County Environmental Health gave the green light for people to enjoy beaches north of the last house on Southeast Drive in Imperial Beach. But Pasculli was right in the middle of the 'Red zone,' where the county deemed unsafe due to Tijuana sewage contamination since last November. That did not seem to bother him. “The way I look at it, we’re pretty close to that last house, so I think we’re in a gray zone, so I’m not worried about it,” Pasculli said. Surfer Dane Crosby was not phased by the warnings either.“It’s a north swell today, so I know that the water is moving south," he said.The Imperial Beach resident already surfed the waters in the morning. He was at the beach again, walking his dog Dixie.“When it is dirty, you’ll get an essence of detergent, kind of like a peppery detergent smell,” Crosby said. But today, he did not smell anything. Neither did Pasculli. They are both confident that the winds and waves will filter away the contaminants.“I think sometimes people get over anxious about things because we’ve become such a germaphobe society,” Pasculli said. “The ocean is pretty active today, so I think it's going to clean itself out.” 1950

If you think Charleston, South Carolina, has plenty of history within its pre-Colonial grounds, just look at what's been hiding 160 miles off the city's coast for thousands of years: a giant deep-sea coral reef system. The chief scientist who helped make the discovery called it unbelievable. 300

If the lyrics to "Let It Go" have been stuck in your head since 2013's "Frozen," new songs are right around the corner.Kristen Bell, who voices Anna, the younger sister of Princess Elsa [Idina Menzel] from the hit animated Disney film, shared a "Frozen 2" update on Thursday during an appearance on "Ellen.""I have recorded the movie," Bell said. "There will be edits before it's finished. I know the songs, I know the story. It's very good!"The film also features the return of Josh Gad [Olaf] and Jonathan Groff [Kristoff]."Frozen" grossed more than billion in the worldwide box office and became Disney's highest-grossing animated film of all time."Frozen 2" releases in theaters November 27, 2019.  718