徐州做四维那个好(徐州无痛胃镜大约多钱) (今日更新中)

If you’re a fan of tequila and cheap drinks, Applebee’s is offering a deal you can take advantage of all-August-long!Through the end of August, Applebee’s is serving up strawberry margaritas (or, more appropriately nicknamed “Strawberry Dollaritas”). To put into perspective, their all-day-long special is less than the price of a soda! The drinks are served in a frosty 10-ounce mug on the rocks with tequila, strawberry and margarita mix — the perfect combination to cool down during the sweltering hot summer.Operating hours and participating locations may vary so before heading out to your favorite Applebee’s location, the company suggest reaching out and making sure they offer the deal. 710

How accurate are the coronavirus tests used in the U.S.?Months into the outbreak, no one really knows how well many of the screening tests work, and experts at top medical centers say it is time to do the studies to find out.When the new virus began spreading, the Food and Drug Administration used its emergency powers to OK scores of quickly devised tests, based mainly on a small number of lab studies showing they could successfully detect the virus.That’s very different from the large patient studies that can take weeks or months, which experts say are needed to provide a true sense of testing accuracy.The FDA’s speedy response came after it was initially criticized for delaying the launch of new tests during a crisis and after the Centers for Disease Control and Prevention stumbled in getting its own test out to states.But with the U.S. outbreak nearly certain to stretch on for months or even years, some experts want the FDA to demand better evidence of the tests’ accuracy so doctors know how many infections might be missed.There have been more than 2 million confirmed coronavirus cases in the U.S. and more than 115,000 deaths, according to data compiled by Johns Hopkins University. Cases in nearly half of U.S. states are rising.In recent weeks, preliminary findings have flagged potential problems with some COVID-19 tests, including one used daily at the White House. Faulty tests could leave many thousands of Americans with the incorrect assumption that they are virus-free, contributing to new flare-ups of the disease as communities reopen.“In the beginning, the FDA was under a lot of pressure to get these tests onto the marketplace,” said Dr. Steven Woloshin of Dartmouth College, who wrote about the issue in the New England Journal of Medicine last week. “But now that there are plenty of tests out there, it’s time for them to raise the bar.”The FDA said in a statement that it has already asked multiple test makers to do follow-up accuracy studies, although it didn’t say for how many of the more than 110 authorized screening tests. The agency also said it is tracking reports of problems. Accuracy has also been an issue with blood tests that look for signs of past infections.No screening test is 100% accurate. So details on accuracy are routinely provided for tests of all types, including seasonal flu, hepatitis, HIV and cancers. For example, rapid flu tests are known to miss 20% or more of all cases, a factor doctors weigh when treating patients who have symptoms but test negative.For now, most COVID-19 tests in the U.S. don’t give data on real-world performance, including how often the tests falsely clear patients of infection or falsely detect the virus. That information is lacking for all but a few of the roughly 80 commercial screening tests available, according to an Associated Press review.The government’s emergency authorization process “requires a lower level of evidence,” the agency said. Makers need only show that a test “may be effective” instead of the usual requirement to demonstrate “safety and effectiveness.” They would have to meet that higher threshold once the U.S. government declares the emergency over.Many of the commercial test makers submitted results from 60 samples, the minimum number required and mostly used lab-produced specimens of the virus. The FDA now recommends the use of nasal swabs or other real samples from people screened for coronavirus.Experts say larger patient studies patients are needed to assess a test’s true performance.Lab testing bears little resemblance to actual — sometimes imperfect — conditions at hospitals, clinics and testing sites noted Dr. Robert Kaplan of Stanford University.“You’re testing people in parking lots, the patients themselves are extremely anxious and often unable to follow instructions,” said Kaplan, a former associate director of the National Institutes of Health.Kaplan and others say those differences could explain why some tests are not performing as expected.Last month, the FDA warned doctors of a potential accuracy problem with Abbott Laboratories’ rapid ID Now test, which delivers results in roughly 15 minutes. The test has been lauded by President Donald Trump and used to screen the president, his staff and visitors to the White House.The FDA alert followed a preliminary report by New York University that found Abbott’s test missed between a third to one-half of infections caught by a rival test in patients screened for the virus.Abbott rejected the findings, saying the researchers did not follow the instructions for using its test. The company pointed to alternate patient studies, including its own, that have found the test successfully detects between 91% and 95% or more of virus cases when compared to other tests.But similar problems with ID NOW’s accuracy have been flagged in preliminary reports by researchers at Stanford University, Loyola University and the Cleveland Clinic.For now, the FDA is requiring Abbott to conduct follow-up studies in several different patient groups.The FDA’s emergency standards “are still high but there is a significant difference in the body of work that what would go into a submission under the normal process,” said Abbott vice president John Hackett. “Our normal process takes years to bring these out.”Requiring bigger studies of all coronavirus tests could provide valuable information, but it could also strain the FDA’s already stretched staff and resources, said Dr. Daniel Schultz, former director of the FDA’s medical device center.Dr. Colin West of the Mayo Clinic worries doctors and patients have put too much confidence in the current crop of tests, when an unknown number of patients with COVID-19 are likely receiving false negative results.Even a modest error rate can have grave consequences during an outbreak like COVID-19. West gives the example of a test that is 95% accurate at detecting the virus and is used on 1 million people. That would still result in 50,000 people being incorrectly told that they don’t have the virus.“The negative test does not mean that I’m off the hook,” West said. “We just need to maintain that level of vigilance until we have a better sense of how good these tests really can be.”___Follow Matthew Perrone on Twitter: @AP_FDAwriter.___Follow AP pandemic coverage at http://apnews.com/VirusOutbreak and https://apnews.com/UnderstandingtheOutbreak.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 6604

ICYMI: The 2020 @ArmyNavyGame, presented by @USAA, will return to West Point for the first time since 1943.?? https://t.co/mdSCEyVfXc#GoArmy | #BeatNavy | #ArmyNavy pic.twitter.com/7405S9SIDG— Army Football (@ArmyWP_Football) October 23, 2020 250

IMPERIAL BEACH, Calif. (KGTV) - A new event venue is honoring the history of the South Bay, while giving people a gorgeous view for their parties and meetings.Salt Drift Pointe, at 536 13th Street, has 13,000 square feet of space. It includes a main room, a bar, patio, pier and more."It's a huge blank space," says Co-Owner Richard Inunza of the venue. "We've got a great atmosphere and great views."Inzunza and his co-owner Terry Snyder designed the venue specifically to try and pay homage to the South Bay. The "rustic wall" in the event space is painted to reflect the colors of the bay. And the name, Salt Drift Pointe, refers to the industrial history of the region.RELATED: New Chula Vista event space highlights city's rich history"When Rich and I thought about the name for this place, we wanted to grab the natural landscapes," says Snyder. "As you can see from the beautiful views we have of the salt ponds and the old salt mines, we wanted to include the salt."Salt played a big part in the South Bay story. According to San Diego History Center Historian Andy Strathman, it was the first industry that helped the region shift away from a farm-based economy during the late 1800s."You could build very large settling basins to bring the saltwater in and allow it to evaporate over time," says Strathman. "You would get the water increasingly saline, and eventually, you could harvest the salt."In the 21st century, the South Bay has shifted its economy again, trying to attract more tourists. The new Chula Vista Bayfront project is expected to bring in more than billion every year once it's completed.Inzunza and Snyder say it's fitting that a new business like theirs, which will tap into the hospitality industry, honors the past."We hope families can come and enjoy this place for years," says Snyder.To celebrate, Salt Drift Pointe is hosting a free grand opening party on Oct. 30. The public is welcome to stop by and take a look at the new venue from 5 - 8 p.m. 1993

House Republicans are announcing they're leaving office at a significantly faster rate than any other recent Congresses, suggesting Democrats could pick up seats in the 2018 midterm elections. On Wednesday, CNN reported House speaker, Wisconsin Republican Paul Ryan, would be next.Already, at least 42 House Republicans have announced they are retiring, running for another office or resigning outright, including Ryan. They're leaving from all over the map, from southern New Jersey to southern New Mexico.Democrats need to pick up 24 House seats to retake the majority from Republicans, who've had control of the House since 2011.Republican leadership has acknowledged it has a problem."We've got to find better ways to empower people where they feel like this is worth their time," Rep. Pete Sessions of Texas, a former two-term National Republican Congressional Committee chair who met with several members to discuss retirements, told the National Journal in September.But the retirements kept coming.While midterm elections are historically tough for the party of the President in power, it's too early to tell how things will unfold this year. But seats are opening up all over. A few seats will be filled by special elections before next November. But most won't.The locations of some of these seats were pivotal during the push for health care reform and tax reform in 2017. Reps. Frank LoBiondo of New Jersey and Charlie Dent of Pennsylvania were courted during the health care debates for their votes. Both have high numbers of Medicaid enrollees in their districts. Property taxes are high in New Jersey, and LoBiondo objected to the repeal of the state and local tax deduction during the tax reform debates.Some states are seeing higher numbers of open seats. And not all of the vacancies are coming from Republicans. Several vacancies opened in Texas, including the blue 16th Congressional District, won by Democrat Beto O'Rourke in 2016. He announced that he plans to run for the Senate in 2018.Seats have opened as a result of sexual harassment inquiries or accusations. Among Democrats, Reps. Ruben Kihuen of Nevada and John Conyers of Michigan announced they would leave Congress following pressure to resign, though Kihuen plans to finish his term. On the Republican side, Rep. Trent Franks of Arizona resigned and Rep. Blake Farenthold of Texas announced he will resign, both following sexual harassment accusations.The campaign committees on both sides of the political aisle are eyeing the 23 Republicans defending districts that Hillary Clinton won in 2016 and the 12 seats held by Democrats in districts that President Donald Trump won. These are seen as vulnerable seats to flip.But many of the Republican retirements are occurring in districts where Trump narrowly carried the vote, like New Jersey's 2nd or Michigan's 11th. Members from these districts could have faced tough re-elections this year, when Democrats are expected to be strong performers, potentially regaining control of the House.Republicans who say they will run for other offices are more likely to come from districts where Trump performed well. These members vote in alignment with the President at a high rate. They may count on continued support from his base to propel them into higher office.With few exceptions, the Republicans and Democrats who are retiring largely vote along party lines. They also have levels of support for the President's agenda similar to those of their respective parties.Past research has found the emergence of "strategic retirement" by politicians when they think re-election is less likely. The recent results in Virginia and subsequent Republican departures suggest this phenomenon may be in effect.Here is the full list of representatives so far who have announced that they plan to leave office, broken down by whether they said they will resign, retire or run for another office. Some members resigned before their terms ended.While the number of Democrats and Republicans planning to run for another office is close in number, the number of House Republican retirements dwarfs those announced by Democrats. Members from either party planning to run for another office tend to run for Senate seats or governorships.Scandal has also led to some resignations. Rep. Tim Murphy of Pennsylvania announced he would retire after the anti-abortion GOP congressman admitted that he had had an affair and had urged an abortion.  4465

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