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SAN DIEGO (CNS) - A COVID-19 vaccine trial sponsored by drugmaker Johnson & Johnson is slated to get underway soon in San Diego, and will include an estimated 2,000 participants at UC San Diego Health, it was announced Thursday.Up to 60,000 participants will be recruited from 10 different countries around the world as the San Diego portion of the trial, dubbed ENSEMBLE, gets underway Oct. 7, according to UCSD.The efficacy, safety and immunogenicity of the drug Ad.26-COV2.S will be tested via a randomized, double-blind, placebo-controlled study, in which half of the participants receive a single-dose injection of the vaccine and the other half receive a placebo. All participants -- who must be 18 years of age or older and in reasonably good health -- will be monitored for signs of infection and COVID-19 over the next two years, according to UCSD.Researchers are particularly interested in recruiting participants at increased risk of SARS-CoV-2 infection due to where they live, their age or personal circumstances, such as working in essential jobs like first responders, health care, maintenance, construction, grocery stores or assisted living facilities.The San Diego trial will also emphasize participation from the region's underserved communities, as communities of color have shown higher rates of COVID-19-related hospitalization and/or death.UCSD cited data from the county showing measurably higher infection rates in the South Bay, including in Chula Vista, Imperial Beach and National City.Susan Little, professor of medicine at UC San Diego School of Medicine and principal investigator of the UC San Diego trial, said, "Many communities of color are experiencing higher rates of hospitalization related to COVID-19 than are observed in white, non-Hispanic people. It is important that these communities are represented in COVID-19 vaccine clinical trials so that we understand if the vaccine will work well within these groups."For more information about participating in the trial at UC San Diego, go to www.covidvaccinesd.com or call 619-742-0433. 2087

SAN DIEGO (CNS) - A former executive for an Orange County genetics company pleaded guilty today to a federal conspiracy charge for paying kickbacks to physicians.Donald Joseph Matthews, 50, formerly the vice president of market development for Proove Biosciences, admitted in San Diego federal court to paying doctors at least .5 million to order the company's DNA tests for their patients, according to the U.S. Attorney's Office.In total, the U.S. Attorney's Office said Proove billed around million to the Medicare program for the tests -- which the company alleged could determine a patient's risk of drug addiction -- and received around million in reimbursements.Prosecutors said the company claimed the payments were compensation for participation in a clinical research program, but the money was actually "directly tied to the volume of tests that a doctor ordered and whether a doctor continued to order more tests from Proove over time.''In his plea agreement, Matthews admitted that without the financial compensation, ``most doctors were not interested in ordering Proove's tests for their patients.''Doctors who complained about not being paid were told to order more tests, according to the U.S. Attorney's Office.The company's Irvine headquarters was raided by federal authorities in 2017.``Our nation's healthcare system cannot tolerate kickbacks to physicians while criminals line their pockets with taxpayer-funded healthcare dollars, particularly in light of our nation's current struggles with the COVID- 19 pandemic,'' said Acting Special Agent in Charge Omer Meisel of the FBI's San Diego Division.Matthews is scheduled to be sentenced Oct. 26. He faces a maximum penalty of five years in prison and a 0,000 fine, according to the U.S. Attorney's Office. 1798

SAN DIEGO (AP) — A federal judge has extended a freeze on deporting families separated at the U.S.-Mexico border, giving a reprieve to hundreds of children and their parents to remain in the United States.U.S. District Judge Dana Sabraw said in his order Thursday that "hasty" deportation of children after reunification with their parents would deprive them of their right to seek asylum.The American Civil Liberties Union had requested families be given at least a week. The judge's order did not specify a date for when the reprieve would end.RELATED: Trump admin outlines plan to reunify separated children with deported parentsThe government has opposed the move, saying parents waived the rights of children to pursue asylum claims after signing deportation forms. Both sides were to discuss the decision at a hearing Friday.The order to extend the freeze, which Sabraw first put in place July 16, affects many of the more than 2,500 children who were separated from their parents.In his ruling, Sabraw said delaying the deportations "would not unfairly or unduly tax available government resources," but that carrying out the removals would go against the public's interest in upholding the country's laws and protecting the rights of immigrants and asylum seekers.RELATED: San Diego judge upholds ban on deporting reunited migrant familiesHe said claims of people persecuted in their homelands should at least be heard. Many of the families have said they were fleeing violence in their home countries in Central America and planned to seek asylum."The Court is upholding the rights provided to all persons under the United States Constitution, rights that are particularly important to minor children seeking refuge through asylum, and rights that have been specifically recognized by the President's Executive Order in the particular circumstances of this case," Sabraw wrote.In late June, Sabraw ordered that children under 5 be rejoined with their parents in 14 days and children 5 and older be rejoined in 30 days.RELATED: Ivanka Trump says family separations issue 'was a low point'The order came days after President Donald Trump, amid public outrage at children being taken from their parents, halted the "zero-tolerance" policy implemented in the spring that split families up at the border.As of Aug. 16, the government had reunified 2,089 children with their parents or to others, including sponsors. Nearly 600 were still separated, including 366 with parents outside the U.S. 2504

Sam’s Club is going to hire 2,000 seasonal workers to aid with the upcoming holiday season.In a press release, the retail company said they are looking for extra help as they gear up for more days of deals and an influx in shoppers.“We take our cues directly from our members, and they’re telling us they’re ready for and excited about holiday shopping this year,” said Megan Crozier, Chief Merchandising Officer, Sam’s Club in the news release. “Our merchants are making this holiday extra special for our members across categories – from food and holiday décor to one-of-a-kind gifts – with more high-quality items at amazing members-only values, and special experiences they can’t find anywhere else.”The positions will be in their fulfillment and distribution centers.Sam’s Club said the positions would be full-time. Fulfillment center hourly associates will be paid an extra an hour during the holiday season, the company said. 944

SAN DIEGO — Corinne Lam didn't waste anytime once she learned she wouldn't be allowed to cut hair indoors anymore.She spent Monday afternoon gathering tents, misters, and rugs to make it somewhat bearable to move Rancho Bernardo’s Salotto Salon’s operations into its parking lot."We were essentially ready to start operating tomorrow outdoors,” she said Tuesday.Governor Newsom on Monday ordered salons, gyms and malls to cease indoor operations to slow the increasing spread of Covid-19.Lam didn't think moving outside would be a problem. After all, the County of San Diego said businesses could shift operations outside under tents, canopies or sun shelters if the sides are not closed and there is sufficient air movement.Lam, who owns the salon with her husband, was planning to do just that until she learned the California Board of Barbering and Cosmetology won’t allow it.“The law - in the Business and Professions Code - states that all barbering and cosmetology services must be performed IN a licensed establishment,” said Cheri Gyuro, spokeswoman for the state Department of Consumer Affairs. “Therefore, these types of business in the required counties must be closed immediately.”It's a devastating blow to Salotto Salon and those like it across the county - because unlike last shutdown, they've exhausted all of their stimulus funds through the paycheck protection program.“We're not just hairstylists,” Lam said. “We are professionals and business owners and mothers, and all we want is to be able to do what we do.” 1540