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The drug ketamine is used as an anesthetic, a pain reliever or even a club drug. But now, a ketamine-like drug could soon be approved by the FDA to help people fighting severe depression. Sally Owens is one patient undergoing ketamine treatment. “You feel secure in and grounded, even though you're in a dream state,” Owens says of the treatment. “And in an hour, you come out of it and you're feeling better.” The retired nurse started getting IV ketamine treatments after fighting depression with antidepressants for most of her adult life, with no success. But after two sessions at Vitalitas, a Denver ketamine infusion center, she saw results. “I was doing more things around the house and getting out and and doing more things with friends,” she says. Owens says she’s excited to hear the FDA is considering a more accessible, less potent nasal spray similar to ketamine. “You could essentially think of esketamine as half of ketamine,” describes Dr. Roman Langston, who treats patients with ketamine. Esketamine would be for people with severe depression who haven't benefited from at least two different therapies, the doctor says. 300 million people around the world are affected by severe depression. Drug makers hope the spray can help 30 to 40 percent of patients, who don't respond to antidepressants. Antidepressants can take weeks to take effect, while they say nasal spray benefits start after four hours. Dr. Langston says FDA approval could make more people comfortable using the drug, commonly known as a party drug. Right now, it's not covered by insurance. Sessions can range from 0 to 0 for a session. “If they qualify for coverage through their insurance company, maybe it's a copay, and they can give it a try and it could make a huge difference in their life,” he says.Dr. Langston says it remains to be seen what the long-term consequences of esketamine are. 1907
A group of Good Samaritans — all of them dressed in furry animal costumes — helped police arrest a man suspected of domestic violence on Friday.The incident took place outside of the San Jose Convention Center on Friday, just as FurCon was ending for the evening. FurCon is a convention for "furries" — a subculture of people interested in dressing up and cosplaying in animal costumes.According to 411

Researchers are trying to find out as much as they can about great white sharks.After a couple of attacks involving people last year, there are new efforts to learn more about these animals. It’s moments like the incident at Nauset Beach South that shark experts are studying more closely. Video taken of the beach shows white sharks feeding on seals close to the shore. Now, researchers are launching new studies, including one looking at the feeding habits and behaviors of these sharks. “We're essentially going to be giving iPhones to white sharks to track their activity in three dimensions at a really fine scale,” explains Megan Winton, a research scientist with the Atlantic White Shark Conservancy. Winton and other researchers will be tagging sharks with devices similar to what's in smartphones. “We'll be able to identify how often they're feeding on seals. We'll be able to look for relationships with feeding activity and environmental conditions,” Winton says. The data would be given to officials to use to provide better warnings on beaches. The Atlantic White Shark Conservancy is currently pouring over data on a population study they just finished. “Based on the video footage, we were able to identify every shark we saw to an individual level,” Winton says. So far, the researchers have identified more than 300 white sharks. Winton calls it a conservation success story, thanks to protections put in place over the last few decades. “So one thing I like to remind people is that these are large, amazing animals and they're very capable predators and they're certainly deserving of our respect,” Winton says. “But they're not monsters out there, lurking our coastline menacing our beaches. They're big fish out there eating their natural prey item.” White sharks are the only natural predator to seals in the Cape Cod area, which some residents and fisherman see as a nuisance.Researchers want to see how many seals the sharks are eating and if they can impact the seal population. 2023
A lot of things have changed at Disneyland since 1985.For starters, Captain Jack Sparrow is now the star of the Pirates of the Caribbean ride, and you can buy and drink alcohol inside Oga's Cantina.But one thing hasn't changed: Canadian woman Tamia Richardson's love for Disney.In August 2019, the park honored visitor Richardson's free entry pass from 1985. Although decades have passed since Richardson received the pass, she was allowed in without so much as a surcharge.Richardson, who lives in the Edmonton suburb of Sherwood Park, Alberta, was planning a girls' trip to Disneyland with her mother, aunt, and daughters Mia and Maren when she found the coupon.The mom of two first visited Disneyland in 1985 when she was 14 years old. That was also the year that Disneyland, located in Anaheim, California, celebrated its 30th birthday.In 1985, admission tickets cost .50. These days, the most basic single day admission ticket costs ."As part of the 30th Anniversary, Disneyland featured the Gift Giver Extraordinaire, which gave out prizes to every 30th guest," a Disney spokesperson explains to CNN Travel. "Tamia won a pass to use for a return visit. She kept the pass for 30 years and used it today for admission.""Disney's big in our family," says Kent Richardson, Tamia's husband, who has been keeping the home fires warm back in Canada. "They're having the time of their lives."Still, not every old pass or ticket that you find buried in the attic will necessarily be honored at the House of Mouse.Passes that are confirmed not to be copies and that do not have expiration dates will be accepted for entrance into Disney parks, while "A B C D E" tickets (used for admission to individual rides or attractions) are not good for general admittance.In the past, some Disney staffers have reportedly used a "Book of Life" if they needed to verify a particular pass. 1891
This street in Denver is quiet. And that’s why things seemed a little off to Judy Plok last summer, when she saw what was going on at this house. “It was obviously a party house,” said Plok, who lives near the house in question. She and the rest of the neighborhood soon discovered this house was an Airbnb rental, and new guests were coming in every weekend to have a good time. “One Saturday afternoon, the people who were there enjoying themselves got out on the roof. There’s several different levels, and they were jumping off the roof into the pool. if you’re going to party, you’re not going to sit around quietly enjoying a sip of tea,” said Plok. So she and her neighbors decided to do something about it. They contacted the city attorney and took the owner of the house to court. “The judge found in our favor, so we were pleased with that,” said Plok. The house is no longer an Airbnb, and Plok said the neighborhood is quiet again. Orinda, California, is a lot like this street in Denver. It’s quiet and families love it. The town is having issues with Airbnb, too, but, they are far more serious. The day after Halloween, Mayor Inga Miller said she got a phone call no mayor wants to get. There was a shooting at a house party and five people were killed. Miller said she had the same reaction most would, but as mayor she had a job to do as well. “So as those facts developed Friday morning, we set about changing our agenda for the Tuesday meeting to direct staff to include an item on our short term rental housing program,” said Miller. A meeting she knew the town would turn out for. Dozens did, and the meeting was emotional. Soon after, Airbnb responded with a list of reforms: Plans to review every unit A 24/7 hotline for neighbors and what they call a “high risk human review”A look at people who might be high risk reservationsAll in an effort to ban house parties “When I heard Airbnb wanted to ban house parties, I thought, good luck with that. That’s like parents going away and telling their teenage kids, don’t have any parties when we’re gone. How are they going to control that?” said Cheri Young, who is a professor of hospitality at the University of Denver. She’s not sure the ban is enforceable, and she’s not the only one. “I think that’s fine as long as someone defines what a house party is,” said Plok. “You don’t have control over what’s going on in the actual unit, it’s almost impossible. How are they going to know how many people are in there? Do you want Airbnb hosts putting cameras up, inside the home?” said Young. As for Orinda, the city plans on taking action. “An interim ordinance, an urgency ordinance, that would allow us to immediately ban non hosted short term rentals, for a period of 45 days, which time could be extended up to two years, while we look at more long term solutions,” said Miller. 2877
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