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ISLAMABAD, Oct. 15 (Xinhua) -- President Asif Ali Zardari said on Saturday that the government was committed to address the issues of special people including those afflicted with impaired vision and blindness and called for establishing highest standards for their care.In a message on the International White Cane Safety Day, the President asked the people and relevant government agencies to reflect on the problems of visually handicapped people.He asked them to come up with suggestions to achieve high standards in caring for the disabled as these exist in other civilized nations.The White Cane Safety Day was aimed at creating awareness about the problems and requirements of visually handicapped persons and to take practical steps to address these issues. Enditem

BEIJING, Nov. 10 (Xinhuanet) -- Awareness in three vegetative patients were detected in a portable electrode test, a new study shows. If replicated, the method may change standards in treating such patients.The new study, published online in the journal The Lancet Wednesday, was reported to be the first to detect signs of awareness in patients living in the unresponsive state through more accessible electroencephalogram (EEG) machine.The EEG is a portable and more affordable technique than Magnetic Resonance Imaging (MRI) scanner, but it is as effective as the MRI to diagnose patients in the vegetative state, according to the research team led by Damian Cruse and Adrian M. Owen of the University of Western Ontario.In the research test, the team hooked 16 previously determined to be vegetative patients to EEG machines and gave simple instructions to them like moving their fingers and toes.The machines show that the patterns in the premotor cortex, the area of the brain that plans and prepares movements, in three of 16 patients were exactly the same as those of healthy volunteers.While the patients were able to follow simple instructions, they were not able to make their own decisions about their state, the researchers said.

WASHINGTON, Oct. 9 (Xinhua) -- U.S. researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication Sunday in Nature Biotechnology, researchers describe using small interfering RNA technology to silence the biochemical signals that attract a particular group of inflammatory cells to areas of tissue damage."The white blood cells known as monocytes play a critical role in the early stages of the immune response," says Matthias Nahrendorf, of the Massachusetts General Hospital (MGH) Center for Systems Biology, the paper's senior author. "We now know there are two subsets of monocytes -- an inflammatory subset that defends against pathogens and a reparative subset that supports healing. But if the inflammatory response is excessive, it can block the healing process and exacerbate conditions such as heart disease and cancer."Cells damaged by injury or disease release a cocktail of chemicals called cytokines that attract immune cells to the site of the damage. Inflammatory monocytes are guided to sites of tissue injury by a receptor protein called CCR2, and the MGH-led team devised a strategy targeting that molecule to block the inflammatory process but not the action of the reparative monocytes.Small interfering RNA (siRNA) technology prevents production of specific proteins by binding to associated messenger RNA molecules and preventing their translation. However, the technique requires extreme precision in developing the right siRNA molecule and delivering it to the correct cellular location.To make sure that their siRNA preparation targeted the right monocytes, researchers first confirmed that its use reduced levels of CCR2 in monocytes and increased levels of the fragments produced when siRNA binds to its target. They then showed that monocytes from mice treated with the siRNA preparation were unable to migrate towards CCR2's usual molecular target. Experiments in animal models of several important diseases showed that the siRNA preparation reduced the amount of cardiac muscle damaged by a heart attack, reduced the size and the number of inflammatory cells in atherosclerotic plaques and in lymphomas, and improved the survival of transplanted pancreatic islets."These inflammatory monocytes are involved in almost every major disease," Nahrendorf explains. "Anti-inflammatory drugs currently on the market hit every inflammatory cell in the body, which can produce unwanted side effects. This new siRNA treatment doesn't affect inflammatory cells that don't rely on the CCR2 receptor. That makes a big difference."

CAPE TOWN, Nov. 13 (Xinhua) -- The research vessel SA Agulhas has set off from Cape Town on a 10-day polar tour intended to promote dialogue on climate change, authorities confirmed on Sunday.The trip was designed to mark the 17th Climate Conference of the Parties (COP17) to be held in Durban later this month, according to the Department of Environmental Affairs.The voyage, which set off Saturday noon with scientists, academics, students and journalists aboard, would host exhibitions, symposiums and lectures from climate change scientists on the work of the polar research vessel, spokesman Zolile Nqayi said in a statement.The exhibitions and lectures would also highlight the various scientific activities undertaken by the department and its partners in Antarctica and the Southern Oceans, according to the South African Press Association (SAPA).Apart from her research and supply work, the Agulhus also helped to rescue the Magdalena Oldendorff, which became stuck in thick ice in June 2002.In December the SA Agulhas would make its final voyage to Antarctica before retirement.The Agulhas, which has been in service for 33 years, would be replaced by a new vessel under construction in Finland."She served us very well," said Dr Monde Mayekiso, deputy director general of oceans and coasts."The new vessel will have enhanced technologies and capabilities to further understand the ocean environment and to bring that understanding to an increasing number of South Africans, " he said.

BEIJING, Dec. 11 (Xinhua) -- China is faced with severe challenges in collecting enough blood plasma to produce medicines, Health Minister Chen Zhu said Sunday.Chen called on the public to join blood donation after donating blood plasma at the Beijing Red Cross Blood Center on Sunday, the fifth time since he took office in 2007.Blood plasma is needed to make blood products like prothrombin complex which is vital for hemophiliacs.The total volume of blood plasma collected last year was 4,180 tonnes, while the volume needed to produce enough medicines was 8,000 tonnes, said a statement from the ministry. The situation became even worse this year.Donations of blood plasma in China fell dramatically in recent years, as a result of safety concerns from donors and the government's efforts to regulate blood collection after contamination triggered HIV infection scandals.In an overhaul of plasma collection services in 2004, the ministry closed 262 donation centers, leaving only 138 in operation, resulting in the plasma donations falling at least one-third from 5,000 tonnes in 2003.Blood plasma are currently collected at 144 designed stations across the mainland. The stations, as requested by law, are all owned by major manufacturers of blood products.Chen promised to encourage qualified drug makers to set up more collection stations in the next five years.He also assured the public the safety of blood donation at authorized stations.