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The day after President Donald Trump signed a historic peace agreement with world leaders and attended a town hall event in Philadelphia, there are reports White House staff members may have tested positive for COVID-19.During his White House briefing on Wednesday, President Donald Trump confirmed that one person, who is part of the WH staff, tested positive for the coronavirus.A reporter for Globo, a Brazillian media outlet, who is part of the White House press corps tweeted Wednesday morning that she learned of the positive cases when the corps own testing was late. 582
The Food and Drug Administration released updated safety standards Tuesday for makers of COVID-19 vaccines despite efforts by the White House to block them, clearing the way for requirements that are widely expected to prevent the introduction of a vaccine before Election Day.In the new guidelines posted on its website, the FDA said vaccine makers should follow trial participants for at least two months to rule out any major side effects before seeking emergency approval. That standard had been a sticking point between the FDA and White House officials, who said it could unreasonably delay the availability of COVID-19 vaccines.President Donald Trump has repeatedly insisted a vaccine could be authorized before Nov. 3, even though top government scientists working on the effort have said that timeline is very unlikely. On Monday Trump said vaccines are coming “momentarily,” in a video recorded after he returned to the White House.Former FDA officials have warned that public perception that a vaccine was being rushed out for political reasons could derail efforts to vaccinate millions of Americans.A senior administration official confirmed Monday that the White House had blocked FDA’s plans to formally publish the safety guidelines based on the two-month data requirement, arguing there was “no clinical or medical reason” for it.But on Tuesday, the FDA posted the guidance on its website, making clear that regulators plan to impose the safety standards for any vaccine seeking an expedited path to market.FDA Commissioner Stephen Hahn said in a statement that he hoped the guidelines would help “the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy.”The requirements are aimed at companies seeking rapid approval through the FDA’s emergency authorization pathway. That accelerated process, reserved for health emergencies, allows medical products onto the market based on a lower bar than traditional FDA approval. But FDA has made clear only vaccines that are shown to be safe and effective will be authorized for coronavirus.Former FDA acting commissioner Dr. Stephen Ostroff said the requirements seem reasonable given the agency is in largely “uncharted territory” in terms of considering emergency use of a vaccine. The agency has only previously cleared one vaccine through the method — a decades-old shot that was authorized to prevent anthrax poisoning in 2005.“There really is no margin for error here,” Ostroff said. “Even when you’re talking about limited use of a vaccine there has to be some level of assurance that there isn’t a risk here that would far outweigh the benefit.”Dr. Peter Marks, the head of FDA’s vaccine division, said Tuesday that the two-month follow-up requirement was chosen to be “something reasonably aggressive, but not too conservative — right in the middle.” He spoke at a symposium organized by Johns Hopkins University.Initial doses of vaccines for emergency use would likely be reserved for medical workers and people with health conditions that make them particularly vulnerable to coronavirus. Full FDA approval for the general population will require significantly more data and is not expected until mid-2021.The White House attempt to block the guidance followed a string of instances in which the Trump administration has undercut its own medical experts working to combat the pandemic. FDA’s Hahn has been attempting to shore up public confidence in the vaccine review process for weeks, vowing that career scientists, not politicians, will decide if the shots are safe and effective.Pfizer CEO Albert Bourla has stoked excitement by saying that he expects data on whether the company’s candidate works to be ready in late October. But a number of variables would still have to align for the company to submit, and the FDA to review and greenlight, a vaccine application before Nov. 3. Pfizer’s competitors Moderna, AstraZeneca and Johnson & Johnson are working on longer research timelines.Vaccine development typically takes years, but the U.S. government has invested billions in efforts to accelerate the process and help multiple drugmakers prepare multiple candidates. All the doses will be purchased by the federal government for use vaccinating the U.S. population.Beyond exposing the rift between the White House and FDA, the delay in releasing the guidelines may have had limited practical effect.FDA scientists have been discussing the guidelines publicly for weeks and have made clear that the recommendations have already been shared with each of the vaccine developers.Former FDA Commissioner Scott Gottlieb said Tuesday that drugmakers depend on the FDA’s science-based endorsement to vouch for the safety and effectiveness of their products.“I can’t imagine a circumstance where a sponsor would challenge or seek to undermine the FDA’s role here,” Gottlieb said at the COVID-19 symposium. “This is precisely the moment when we need an objective, neutral arbiter.”Last week, Gottlieb and six other former FDA commissioners blasted the Trump administration for “undermining the credibility” of the agency in a op-ed calling for the release of the then-stalled vaccine guidelines.“Scientists should make decisions based on data, unfettered by political pressure or the intrusions of ideology or vested interests,” the officials wrote.___AP Medical Writer Lauran Neergaard contributed to this report.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 5644

The decades-old sexual assault and murder of a young girl has been solved, thanks to DNA and genealogy records.In September 1982, 8-year-old Kelly Prosser was walking home from school in Columbus, Ohio. Prosser never made it home, and her body was found in a cornfield two days later after her raincoat was spotted.The case went unsolved for decades.DNA evidence from the items collected at the time was entered into CODIS in 2014. There were no hits.Friday, Prosser’s killer was identified as Harold Warren Jarrell, with the help of DNA evidence and genealogical research. Jarrell is now deceased, living relatives helped officers confirm details about Jarrell’s involvement.In 1977, Jarrell was charged with abducting a girl on the north side of Columbus, he was released in early 1982. Jarrell was never mentioned in Prosser’s case file. 848
The E.W. Scripps Company is a partner with The Associated Press and has been following guidance from their election desk on 2020 race updates.Early Wednesday morning, the AP called the presidential race in Arizona for Joe Biden. The state is continuing to count ballots, and in the hours since, President Donald Trump has significantly cut into Biden's lead.Thursday afternoon, officials said there were about 450,000 votes still to be counted in the battleground state. As of 12:30 p.m., Biden had a 2.35 percentage point lead over Trump, an advantage of about 68,000 votes.At 9 p.m. ET, a new trove of votes from Maricopa County, the largest county in the state. Trump gained nearly 11,000 votes, cutting Biden's lead to 46,257. AP executive director Sally Buzbee released the following statement regarding its Arizona projection: "The Associated Press continues to watch and analyze vote count results from Arizona as they come in. We will follow the facts in all cases."All election results remain unofficial until each state verifies its election count.Below is the AP's explanation as to how it made the decision to call the state for Biden.The Associated Press has declared Democrat Joe Biden the winner in Arizona, flipping a longtime GOP state that President Donald Trump won in 2016.The AP called the race at 2:50 a.m. EST Wednesday, after an analysis of ballots cast statewide concluded there were not enough outstanding to allow Trump to catch up.With 80% of the expected vote counted, Biden was ahead by 5 percentage points, with a roughly 130,000-vote lead over Trump with about 2.6 million ballots counted. The remaining ballots left to be counted, including mail-in votes in Maricopa County, where Biden performed strongly, were not enough for Trump to catch up to the former vice president.Arizona has a long political history of voting Republican. It's the home state of Barry Goldwater, a five-term, conservative senator who was the Republican nominee for president in 1964. John McCain, the party's 2008 presidential nominee, represented the state in Congress from 1983 until his 2018 death.But changing demographics, including a fast-growing Latino population and a boom of new residents — some fleeing the skyrocketing cost of living in neighboring California — have made the state friendlier to Democrats.Many of the gains have been driven by the shifting politics of Maricopa County, which is home to Phoenix and its suburbs. That's where Biden sealed his victory. Maricopa County accounts for 60% of the state's vote, and Biden ran up huge margins there.In 2016, Trump carried the county by 4 percentage points, which helped propel him to a win. But two years later, Democratic Sen. Kyrsten Sinema flipped a Senate seat from Republican control by winning the county by 5 points.When the AP called the race for Biden, he was leading there by 9 percentage points.Biden flipping Arizona is a sign of Democrats' ascendant influence in the state.In 2018, Sinema became the first Democrat in three decades to win a U.S. Senate seat in Arizona. Democrats also won three statewide offices and five of nine congressional seats and made gains in the state legislature that year.In 2016, voters ousted Republican Joe Arpaio, Maricopa County's hardline sheriff, who built a national profile on his harsh treatment of immigrants. 3349
The destructive storm surge has receded, and the clean up has begun from Hurricane Laura in Texas and Louisiana. But officials along this shattered stretch of Louisiana coast are warning returning residents they will face weeks without power or water amid the hot, stifling days of late summer. Hundreds of thousands of people in two of the hardest-hit states are reported to be without power following the severe storm.The U.S. toll from the Category 4 hurricane stood at 16 deaths, with more than half of those killed by carbon monoxide poisoning from the unsafe operation of generators. President Donald Trump landed in Louisiana Saturday afternoon to tour the damage in Louisiana and will head to Texas next. 720
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