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SAN DIEGO (CNS) - A man was killed Saturday when an SUV overturned and crashed into a tree on the Sea World Drive on-ramp to northbound Interstate 5, the California Highway Patrol said.The accident happened about 9 a.m. when a white Cadillac Escalade luxury SUV, traveling at a high rate of speed according to one witness, overturned and hit a tree on the right shoulder of the Sea World Drive on-ramp, according to CHP Officer Salvador Castro.Units from the San Diego Fire-Rescue Department were also on the scene, near the Tecolote Canyon Natural Park and Nature Center.The CHP had no immediate information on the identity of the victim. Castro said nobody else was in the SUV at the time of the crash.Traffic on Sea World Drive and northbound I-5 was reported to be slowing. The CHP will investigate the cause of the accident. 837

SAN DIEGO (CNS) - An elderly disabled woman was assaulted and seriously injured in downtown San Diego, police said Saturday.The victim, a 73-year-old homeless woman who uses a walker, was attacked near the corner of Fourth Avenue and B Street at 10:10 p.m. Friday, according to Lt. Matt Dobbs of the San Diego Police Department's homicide unit.She was taken to the hospital where she underwent emergency surgery, the lieutenant said. Because of the serious nature of the woman's injuries, investigators from the SDPD's homicide unit were called to the scene."Detectives are collecting evidence and interviewing witnesses," Dobbs said. "A man was seen in an altercation with the victim. He is described as a Black male in his forties, approximately six-feet tall and weighing 250 pounds."The suspect was wearing a white tank top and blue jeans and was last seen walking eastbound on 400 C Street, Dobbs said.The victim has been identified, but her name was not immediately released.Anyone with information on the attack was asked to call the homicide unit at 619-531-2293 or Crime Stoppers at 888-580-8477. 1113

SAN DIEGO (CNS) - An international team of scientists, led by biologists at the University of California San Diego, has synthetically engineered mosquitoes that halt the transmission of the dengue virus, the university announced Thursday.Scientists at UC San Diego Associate Professor Omar Akbari's lab worked with Vanderbilt University Medical Center to identify a human antibody for dengue suppression. The broad-spectrum antibody stops the transmission of all four known types of the fever, compared to previous experiments, which have been able to limit single strains.The team then designed the antibody "cargo" to be synthetically expressed in the dengue-spreading Aedes aegypti mosquitoes.RELATED: UC San Diego study finds solutions for loneliness"Once the female mosquito takes in blood, the antibody is activated and expressed -- that's the trigger," Akbari said. "The antibody is able to hinder the replication of the virus and prevent its dissemination throughout the mosquito, which then prevents its transmission to humans. It's a powerful approach."Akbari works in the Division of Biological Sciences and is a member of the Tata Institute for Genetics and Society.These lab-engineers mosquitoes could be paired with a dissemination system, making it capable of spreading the antibody throughout wild disease- transmitting mosquitoes, Akbari said.Dengue fever is a virus that poses a severe risk to children and older adults in tropical regions in Asia and Latin America. There are an estimated 390 million infections every year, around 500,000 of which lead to Severe Dengue, and 25,000 people die of the disease every year.RELATED: UCSD Health, San Diego Zoo Safari Park team up to save gorilla's eyesightThe Pan American Health Organization recently reported the highest number of dengue cases ever recorded in the Americas. Infecting those with compromised immune systems, dengue victims suffer flu-like symptoms, including severe fevers and rashes. Serious cases can include life-threatening bleeding. No specific treatment exists and thus, prevention and control depend on measures that stop the spread of the virus.This development could go a long way toward limiting the disease's transmission."It is fascinating that we now can transfer genes from the human immune system to confer immunity to mosquitoes," said coauthor of the paper, Dr. James Crowe, Jr., director of the Vanderbilt Vaccine Center at Vanderbilt University Medical Center in Nashville, Tenn. "This work opens up a whole new field of biotechnology possibilities to interrupt mosquito-borne diseases of man."Akbari's lab is now in the early stages of testing methods to simultaneously neutralize mosquitoes against dengue and a suite of other viruses such as Zika, yellow fever and chikungunya. 2789

SAN DIEGO (CNS) - City officials are asking the San Diego Superior Court to review two competing development plans for the city's SDCCU Stadium site in Mission Valley.Both the SoccerCity and SDSU West proposals have garnered enough signatures of support to qualify for the November ballot. Whichever measure receives the most votes -- assuming it exceeds 50 percent -- will win the rights to negotiate with the city to redevelop the Mission Valley site.The City Attorney's Office filed petitions asking the court to determine whether the initiatives "impermissibly exceed the power to act through an initiative, and whether they impermissibly conflict with state law and the San Diego City Charter."MISSION VALLEY COVERAGE: 731

SAN DIEGO (CNS) - A man died in a hospital Sunday of injuries he suffered in a collision with a boat while he rode a Jet Ski in Mission Bay, authorities said.The collision happened at 6:30 p.m. Saturday near the north end of Ski Beach when a man in his 20s from out of state was riding on a Jet Ski with another family member, according to the San Diego Police Department.A boat collided with the Jet Ski and the injured man was taken back to shore by the family member, where CPR was performed and a pulse was eventually detected, police said. He was taken to a hospital, where he died Sunday.Police questioned the driver of the boat, which was taken as evidence. The investigation of the collision is ongoing. The boat driver's name was withheld. 756

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