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CHARLOTTESVILLE, Va. - At the ripe age of 74, scientist Wladek Minor, PhD. is not slowing down anytime soon, especially when it comes to his research to better understand COVID-19.“This is the biggest danger I’ve seen in my lifetime,” said Minor. “This is a real danger, and we shouldn’t underestimate it.”Minor, who is also a professor at UVA’s Department of Molecular Physiology and Biological Physics, recently made a new discovery in the fight against coronavirus.As the lead researcher, Minor and his team of scientists recently discovered a link between a coronavirus treatment and people with diabetes.They found the drug dexamethasone, which is used to lower the risk of death in patients with a severe case of the virus, might be less effective for treating patients with diabetes.“We were trying to explain why the action of dexamethasone is somewhat erratic,” Minor said. “It means it works for some people and [does] not necessarily work for other people.”Minor and his team analyzed data from 373 COVID-19 patients at a hospital from Wuhan, China.Their research determined how a type of protein in our blood, called serum albumin, picks up dexamethasone and carries it through the body.The scientists found that patients who died had lower levels of that protein than those who survived.Those who died also had higher levels of blood sugar, suggesting diabetes may make it difficult for patients to get the benefits of the drug.“We are trying to make as much impact on human life as possible,” said Minor.Dexamethasone has been shown to cut deaths by about 30% for COVID-19 patients who were on ventilators.The steroid was used to help treat President Donald Trump’s bout with the virus, along with other treatments and drugs including remdesivir, which was just approved by the FDA to use on all hospitalized patients.“COVID is now our enemy, and really, it’s the biggest enemy,” Minor said.Scientists said more research is needed to determine the best treatment for COVID-19 patients, especially for those who have diabetes.For more information on Minor’s research, click here.This story was first reported by Antoinette DelBel at WTKR in Norfolk, Virginia. 2180

CARLSBAD (CNS) - A report of domestic violence triggered an hours-long standoff in a Carlsbad neighborhood Friday night into Saturday morning, police said.Around 10 p.m. Friday, a woman called police and said her husband had assaulted her, cut her hand with a knife and threatened to kill her before she could escape, according to Carlsbad Police Lt. Kevin Lehan. The woman also told police her husband was heavily intoxicated.Police headed to the couple's residence, on Juniper Avenue between Interstate 5 and Garfield Street, and found the man had barricaded himself inside, Lehan said.The man wouldn't cooperate with officers and after a few hours, a SWAT team forced entry into the home through the front door and a window, according to Lehan.Officers searched the home and ultimately found the man hiding under a bed. He was taken into custody without further incident.It was determined the man was unarmed when police arrested him, Lehan said. 957

Catastrophic wildfires continue to ravage California, as one blaze nearly doubled in size over the last three days, making it the largest in the state's history.No one has been injured in the Mendocino Complex Fire, which consists of two fires -- the Ranch Fire and the River Fire -- burning around Clear Lake, in several counties in Northern California.Combined, they form the biggest blaze that California firefighters are currently battling. Altogether, the Mendocino Complex Fire has burned 283,800 acres -- growing about 80% since Friday night. As of Monday evening, it was 30% contained and had destroyed 75 residences.The Mendocino Complex Fire has now surpassed last year's Thomas Fire, which burned 281,893 acres in Ventura and Santa Barbara counties, as the largest fire in Cal Fire history.Exhausted firefighters across the state are trying to contain 16 major fires that are burning in hot, dry and windy conditions.On Monday, another fast-moving fire ignited in the state -- this time in Orange County, where firefighters battled the Holy Fire that expanded to more than 4,000 acres. That fire started in the Cleveland National Forest and evacuations in the nearby areas have been ordered, according to the Orange County Fire Authority.Trump blames California's 'bad environmental laws'In Northern California's Shasta County, the devastating Carr Fire claimed its seventh victim Saturday when a Pacific Gas & Electric worker died while working with a crew to restore power, utility spokesman J.D. Guidi said.Over the weekend, the White House approved a disaster declaration for Shasta County, allowing affected residents from the Carr Fire to apply for federal disaster assistance such as temporary housing, home repairs and other programs.At the same time, President Donald Trump blamed the state's environmental laws for the wildfires."California wildfires are being magnified & made so much worse by the bad environmental laws which aren't allowing massive amount of readily available water to be properly utilized," he tweeted Sunday. "It is being diverted into the Pacific Ocean. Must also tree clear to stop fire spreading!"It wasn't immediately clear what California laws Trump was referring to. Henri Grissino-Mayer, a geography professor at the University of Tennessee, said he had "no clue" what Trump was referring to in his tweet."California does NOT divert water to the ocean," he told CNN in an email. "Ridiculous. It's true that water is diverted to the coastal cities for a constant water supply but all such water is used by the coastal communities."More than 14,000 firefighters are battling the wildfires across California."Battling these relentless fires requires a Herculean effort," California Gov. Jerry Brown had written in his request to Trump for a presidential major disaster declaration.Fire crews from Australia and New Zealand arrived in California to help. They came to Redding, on Monday, according to the US Forest Service-Pacific Southwest Region.Parts of Redding were damaged by the Carr Fire, which has burned more than 164,413 acres. The fire was 47% contained as of late Monday, according to Cal Fire.The Carr Fire, now in its third week, is the sixth most destructive in the state's history, having destroyed more than 1,600 structures, according to Cal Fire.Parts of Yosemite National Park closed indefinitelyAnother major fire also burning in Northern California, the Ferguson Fire, extended into its third week.This fire has killed two people and injured 11 others. And it prompted the indefinite closure of some of the most popular parts of Yosemite National Park, officials announced on Sunday."Over the past 48 hours, fire has impacted all of the roads used to access Yosemite Valley, burning dead and downed trees that can become very explosive and fall without warning," according to the National Park Service.Yosemite Valley is home to some of the most famous destinations of the park."There are also significant terrain hazards for firefighters. These hazards, along with extreme fire behavior and frequent weather changes, have made this an extremely difficult fire fight," according to the NPS statement.The Ferguson Fire started on July 13. Of the 94,331 acres burned, firefighters have contained 39%, according to authorities.The-CNN-Wire 4320

CHARLOTTE, N.C. (AP) — Police say a fourth person has died after being shot earlier this week during an impromptu celebration in North Carolina. The Charlotte-Mecklenburg Police department issued a release saying Dairyon Dejean Stevenson died Tuesday while being treated for a gunshot wound received during the shooting early Monday. 342

Caesars Windsor has announced that due to ongoing labor disruption and temporary closure, they will be making the "difficult yet necessary" decision to cancel hotel reservations and postpone Total Rewards promotions scheduled for the remainder of May. Performances for May have also been postponed until a currently undetermined date. These include: Pitbull, May 25; Le Brice, May 26; and Daniel O'Donnell, May 27. 432

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