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This time, the bomb could have maimed anyone walking through this quiet Austin neighborhood.For the fourth time this month, a device exploded on residents in the Texas capital. What makes this blast especially terrifying is that it was left on the side of a residential road and may have been triggered by a tripwire, Austin Police Chief Brian Manley said.The three previous bombs were stuffed inside packages and left on residents' doorsteps.And unlike the victims of the previous blasts, the two men injured in Sunday's explosion are white, Austin police said. Both men are expected to recover."The use of a tripwire is far less discriminating than leaving parcel bombs at residences and suggests that the latest victims were not specifically targeted," said Stratfor Threat Lens, a global think tank."The device's success, despite significantly different design, further suggests that the bombmaker behind these attacks is an accomplished one, and has likely to have received some training, perhaps as a military or police explosive ordnance disposal technician."This latest attack has even impacted area schoolchildren. The Austin public school district says it can't send buses to the affected neighborhood Monday because of police activity. "Any tardies or absences due to this situation will be excused," the district said. Now, investigators are trying to determine if the person responsible is linked to the trio of bombings this month that killed two people and wounded two others."The entire community is anxious this morning," Austin Mayor Steve Adler said Monday.Austin bombings: Live updates Latest developments 1633

Three students who gave their lives when a gunman opened fire inside a Florida high school will be awarded Medal's of Heroism by the U.S. Army, a spokesperson told Scripps station WFTS in Tampa.According to the U.S. Army, "The Medal of Heroism is a U.S. military decoration awarded by the Department of the Army to a JROTC Cadet who performs an act of heroism. The achievement must be an accomplishment so exceptional and outstanding that it clearly sets the individual apart from fellow students or from other persons in similar circumstances. The performance must have involved the acceptance of danger and extraordinary responsibilities, exemplifying praiseworthy fortitude and courage."Related:17 dead in south Florida school shooting, 19-year-old suspect held without bondFlorida school shooting 'hero' JROTC cadet should receive military burial, classmates sayCoach dies after heroically shielding students from gunfire in Florida school shooting 965

There are things you do that may take little thought, like text a friend, FaceTime a relative, or order something off Amazon. But, for many senior citizens, these actions are new."Technology is slowly opening up all these doors to different things. To watch YouTube videos, they’ve never seen anything like that," said Connie Nelson, franchise owner of Visiting Angels.Nelson works with the elderly, who need assistance in their homes. She says introducing this generation that’s used to delayed gratification to technology is playing a huge role in helping them get through this pandemic."I think the biggest surprise for them is how instant it is. They’re used to a phone call, somebody has to answer. This is just instant. You text a grandchild and they text you immediately," said Nelson.The technology Nelson’s at-home caregivers are teaching the senior citizens ranges from texting to ordering groceries from Alexa."They’re sitting there all day, waiting. They’re waiting for a phone call or they’re waiting for a visit, and sometimes they don’t come because everybody’s busy. But once you hand technology to them, the response is there," said Nelson.And while most of this education is for entertainment purposes, Nelson says they’re walking patients through telemedicine in hopes they’ll continue using it in the future."I think at first they’re a little standoffish. Like, ‘No, he has to see me, touch me. He has to check my ears.’ And, if they can get past that, they won’t get the physical exam, but you’ll get that face-to-face where you can actually tell him what’s going on. It’s not going to replace all visits, but some it can," said Nelson.Teaching them skills like FaceTime, even using social media like Facebook, is keeping them connected to those who may not be able to visit right now."Once they learn it, it’s so rewarding because they’re staying up to date with what’s going on in their loved ones’ lives," said Nelson.Learning the new tech is helping to cure the loneliness that can come with the COVID-19 pandemic. 2047

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

There was a rare sight at San Diego City Hall on Tuesday.A local developer pitched a massive mixed-use complex with hundreds of homes to the council, in front of mostly empty seats. "Our focus has always been on creating a sense of place for the entire neighborhood," said builder Gary Levitt, of Sea Breeze Properties.Sea Breeze Properties plans to transform a 72-acre site just south of the 56 into hundreds of homes, plus offices, retail, and even a hotel and movie theater. The project, Merge 56, didn't get a single 'no' vote from multiple community planning groups.Some nearby residents even came to the meeting to support the project. But even with that backing, it still took five years just to get the council's unanimous vote of approval Tuesday.Levitt said the delays come from regulations, including environmental impact reports, and cost his company an extra million - about 15 percent of that in city processing fees.Councilman Scott Sherman said that is one reason we're in housing crisis. "At the end of the day all the prices get passed along to the consumer and the price of housing," Sherman said. Levitt said ideally it would take two years for a project to get approved. "It's a very expensive process and at the end of the day you're just playing with paper," he said. The project includes 242 new homes, condos, and apartments. Additionally, 47 of them will be affordable units. Two environmentalists did raise concerns about local impacts but the council didn't acknowledge them in their deliberation. Levitt's work, however, isn't done. He still has a number of permits to obtain. They're administrative, but he estimates it'll be about four months before he breaks ground.   1771