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New studies confirm that multiple types of steroids improve survival for severely ill COVID-19 patients, cementing the cheap drugs as a standard of care.An analysis of pooled results from seven studies found that steroids reduced the risk of death in the first month by about one-third compared to placebo treatment or usual care alone in these seriously ill patients who needed extra oxygen.The work was led by the World Health Organization and published Wednesday by the Journal of the American Medical Association.Based on the results of the studies, the WHO has made two recommendations. The first, it says a strong corticosteroid therapy for 7 to 10 days should be used in patients with severe or critical COVID-19. The second, this therapy should not be used in patients with non-severe COVID-19, because it may increase the risk of death.“In contrast, in patients with non-severe COVID-19, based on data from 1,535 patients in one study, systemic corticosteroids may increase the risk of 28-day mortality,” researchers wrote.Compared to other treatments for COVID-19, these types of steroids are generally low cost, easy to administer and readily available across the globe.“Dexamethasone and prednisolone are among the most commonly listed medicines in national essential medicines lists; listed by 95% of countries. Dexamethasone was first listed by WHO as an essential medicine in 1977, while prednisolone was listed 2 years later,” the WHO wrote.The WHO added that clinicians should exercise caution in use of corticosteroids in patients with diabetes or those who are immunocompromised and could become severely ill do to COVID-19. 1651
NEW YORK (AP) — President Donald Trump's son Eric is willing to comply with a subpoena to testify in a New York investigation into the family's businesses, but only after the November election. Trump lawyers argued in a Thursday court filing that Eric Trump's "extreme travel schedule" related to his father's re-election campaign prevented earlier testifying in Attorney General Letitia James' civil probe. They said they also want "to avoid the use of his deposition attendance for political purposes." According to NBC News, James issued a statement on Thursday saying that "no one is above the law."A message seeking comment was left with James' office. James, a Democrat, went to court last month to compel Eric Trump and other business associates to testify and turn over documents as part of an investigation into whether Trump's company lied about asset values in order to get loans or tax benefits.Trump agreed to testify in July, but backed out two days prior, NBC News reported. 997
NEW YORK (AP) — Disney will sprinkle its pixie dust on the streaming arena Tuesday, as its Disney Plus service debuts with an arsenal of marquee franchises including Marvel and Star Wars, original series with a built-in fan base and a cheap price to boot.The -a-month commercial-free service is poised to set the standard for other services like WarnerMedia's HBO Max and NBCUniversal's Peacock to follow, as major media companies behind hit TV shows and movies seek to siphon the subscription revenue now going to Netflix and other streaming giants.Disney's properties speak to its strengths. Besides classic characters such as Snow White and Pinocchio, Disney has Pixar, Marvel, Star Wars and National Geographic — big names that most people would recognize. Disney Plus will also have all 30 past seasons of "The Simpsons." Original shows include "The Mandalorian," set in the Star Wars universe, and one on the Marvel character Loki.RELATED: Southern California theme parks bring holiday cheer to guestsMelissa Knerr, 26, a criminal defense attorney in Springfield, Missouri, already has Hulu, Netflix and Amazon Prime and wasn't sure she wanted to pay for another one. She said she was swayed by Disney Plus's price tag and its "sheer amount of content.""I really love both the Star Wars and Marvel franchises and I grew up watching classic Disney shows and movies so I do think there will be enough content for me," she said.Marlina Yates, who works in marketing in Kansas City, said she signed up because of her husband's enthusiasm about the Star Wars series "The Mandalorian" and her daughter's "love affair with princesses and everything Disney."Disney Plus's a month price is about half of the Netflix charges for its most popular plan, and there are discounts for paying for a full year up front. Disney is also offering a package bundling Disney Plus with two other services it owns, Hulu and ESPN Plus. That's cheaper than signing up for each one individually.RELATED: Spider-Man will stay in Marvel Cinematic Universe as Sony, Disney reach dealEverything won't be available to stream right away, though, as Disney needs to wait for existing deals with rival services to expire. Recent movies missing at launch include the animated Pixar movie "Coco" and the live-action "Beauty and the Beast." Others like "Maleficent: Mistress of Evil" haven't been released for streaming yet. Disney expects 620 movies and 10,000 TV episodes by 2024, up from 500 movies and 7,500 episodes on Tuesday.Disney has said that it is losing about 0 million in licensing revenue in the most recent fiscal year from terminating deals with Netflix and other services. But Disney is betting that what it makes through subscriptions will more than make up for that — at least eventually.Disney is boosting its subscription base initially with heavy promos, much as Apple TV Plus has done and HBO Max and Peacock plan to do. Members of Disney's free D23 fan club were eligible to buy three years of Disney Plus service up front for the price of two years. Customers of some Verizon wireless and home-internet plans can get a year free.The hope is that subscribers will stick around once they see what the service offers.Long-term success is by no means guaranteed. With a slew of services launching, subscription fees can add up quickly. Consumers might be reluctant to drop an existing service such as Netflix or Amazon Prime to pay for something untested.RELATED: Marvel-themed land to open in 2020 at Disney's California Adventure Park"I can't keep up with so many services. It gets expensive," said William Pearson, a Drexel University student who describes himself as a "massive" Marvel fan but already pays for Netflix, HBO and the DC Comics streaming service.But compared with other newcomers, experts believe Disney will have no problem gaining — and keeping — the 60 million to 90 million worldwide subscribers it is targeting for 2024. It took Netflix twice as long to get to 90 million."Disney Plus has a gigantic array of content and a library that's unmatched, so it feels like an easy addition for consumers to get a gigantic library at that low price," said Tim Hanlon, CEO of Vertere Group.Bernie McTernan, internet and media analyst at Rosenblatt Securities, said Apple's venture into streaming, Apple TV Plus, has to build brand recognition for its new shows, while viewers may have difficulties seeing what HBO Max offers beyond the standard HBO subscription.Disney said it was pleased with a recent test in the Netherlands, in which consumers got to try the service for free, without original content or full library of classics."The service connected with users across all four quadrants, male and female, adults and kids, driven by the breadth of our content and the affinity people have with it," Disney CEO Bob Iger told financial analysts Thursday.Connor Clifton, 29, from Houston, Texas, said he is looking forward to "The Mandalorian" Star Wars series as well as catching up on recent Pixar films."Paying for individual channels is frustrating," he said, "but I want to see the content so I'm willing to pay for it." 5157
New technology could be the way guns are made, and you can use it right in your own home.Starting this week, Americans can start legally downloading instructions on how to use a 3D printer to make their own gun. The guns cannot be traced and there’s no background check required.“This is building a gun in your home by pressing a button, says David Chipman, a former ATF Special Agent and an advisor to the Giffords Law Center to Prevent Gun Violence. “That’s an entirely different thing from past technologies.” Chipman says he worries about the future and 3D guns getting in the wrong hands.“Although the threat might not be immediate, next month, five…10 years, it could really change the landscape on how criminals and terrorists get guns,” Chipman says.But the NRA points out there are laws that prevent violent criminals from even having a gun. 869
NEW YORK (AP) — The U.S. Roman Catholic Church used a special and unprecedented exemption from federal rules to amass at least .4 billion in taxpayer-backed coronavirus aid. In totaling the church's haul, The Associated Press also found tens of millions of dollars went to dioceses whose financial stress was due not simply to the pandemic but also to recent payouts to victims of clergy sex abuse. The Paycheck Protection Program the church tapped was intended to help small businesses and nonprofits pay workers amid a cratering economy. The church maximized its take after lobbying for an exemption that gave all religious groups preferential treatment. That helped make the Catholic Church among the biggest winners in the U.S. government's pandemic relief efforts. 779