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The pandemic has raised awareness about convalescent plasma donation to treat coronavirus patients. But for hundreds of thousands of people who rely on regular plasma infusions to survive, a looming shortage is raising alarm bells.Mother, wife and rare disease advocate Deborah Vick lives with myasthenia gravis, a neuromuscular disorder that disrupts nerve to muscle communication.“The messages are no longer being able to reach the muscles to make them work--whether that is to walk or move or swallow or breathe--it's all interconnected,” described Vick.There is no cure, so every two weeks, she requires plasma infusions.“Being in crisis is the worst time to have to wait for treatment,” she explained. “I know, for me, my treatments are every two weeks and days before my treatment starts, my breathing is extremely labored.”Many types of primary immunodeficiency disorders like Vick’s result in an inability to produce antibodies or immunoglobulin to fight off infection.“There's about 250,000 of us in the United States alone,” said John Boyle, president and CEO of the Immune Deficiency Foundation.Canceled drives and fear of COVID-19 exposure, he says, have contributed to a drop in plasma donations for non-COVID therapy.This comes as the Red Cross says hospital distributions of convalescent plasma have increased 250 percent in November compared to September.“To not meet the rising demand is one thing, but to actually have less plasma is potentially very, very, very problematic,” said Boyle.Experts say it takes seven to 12 months to turn around plasma for patient infusion therapies. We are now nine months into the pandemic and a crisis say some could be around the corner.“There is a growing concern about the ability to meet patient clinical need,” said Amy Enfantis, president and CEO of the Plasma Protein Therapeutics Association.She says while the call for convalescent plasma therapies for COVID-19 has raised awareness, there is still an increased need for other rare-disease patients.“Our companies are making therapies every day for patients who have a perpetual need for plasma,” said Enfantis. “And that is ongoing regardless of a pandemic.”For those who rely on plasma donation and infusion treatment like Vick, it could mean the difference between life and death.“The biggest fear is not having the treatments that keep me alive. I mean, reality is I don't know what kind of life I will have, if any, how it will function without my infusions.”It’s why so many are hoping those who can, will give. 2536
The Oxford University Press, which oversees various dictionaries including the Oxford English Dictionary, has updated their definition of “woman” and “man.”"We have expanded the dictionary coverage of 'woman' with more examples and idiomatic phrases which depict women in a positive and active manner," according to a statement from OUP. "We have ensured that offensive synonyms or senses are clearly labelled as such and only included where we have evidence of real world usage."For example, one of the definitions of “woman” now refers to a “person’s wife, girlfriend, or female lover,” and does not include language tying them to a man.In addition, the definition of “man” and “woman” were updated to include gender-neutral terms and references to “sexual attractiveness or activity.”The changes come after a 2019 Change.org petition that called for OUP to remove “sexist” terms for a woman. The petition cited examples from OUP based on the Oxford English Dictionary’s definition: “I told you to be home when I get home, little woman” and also “Ms September will embody the professional, intelligent yet sexy career woman.”The petition also noted there were 25 examples listed for “man” and only 5 listed for “woman.”OUP told CNN their lexicographers are reviewing examples in his dictionaries to make sure they are more representative. Some synonyms were removed, like “wench”, others were kept but have a label added noting the terms are offensive, derogatory or dated.The definition of “housework” was also updated to remove gender; instead of “she still does all the housework,” an example was changed to “I was busy doing housework when the doorbell rang.” 1673

The Netflix series "13 Reasons Why" increased the suicide risk of suicidal teens treated in a psychiatric emergency department, according to a University of Michigan study.Upon release, the show received backlash for its depiction of suicide, as some critics said it glorified those who took their own lives. In addition, another study showed that the show was tied to a rise in online searches about suicide.“This show has been a real phenomenon, especially among teenagers,” Victor Hong, M.D., medical director of psychiatric emergency services at Michigan Medicine, said in a release. “Its depiction of teen suicide has raised great concern among parents, health providers and educators.” Half of the 87 youths, mostly teens ages 13 to 17, who participated in the survey between 2017 and 2018 had watched at least one episode of the show. Among the 43 who watched it, about half said it heightened their suicide risk.“Our study doesn’t confirm that the show is increasing suicide risk, but it confirms that we should definitely be concerned about its impact on impressionable and vulnerable youth,” Hong said.According to the study, very few parents of those in the sample had watched the series themselves and some were not even aware that their child had watched it. “The data from our sample of teens demonstrated that kids who were at high risk of suicide did not reach out to adults,” Hong said. “They mostly watched the show alone or talked to friends, but they weren’t talking to parents, teachers or school counselors.For more information on the study, click here. 1613
The pandemic has made addiction exponentially worse. Doctors are worried that those who are suffering aren't getting the treatment and help they need, especially as people turn their focus to Covid-19.Ashlynn, 25, is two years "clean." "I love being a mom. It's my favorite thing ever and I love that I’m in recovery,” she said.It's been two years since she walked away from a life that was spiraling out of control and heading for an extremely dark place. “I went through stages of functioning addict, thief, manipulator, prostitute, the person that relapses, the person that overdoses, you name it I went through it,” Ashlynn explains. Her journey with mental illness started when she was a teenager. She was in and out of mental institutions and eventually, rehab. “It wasn’t that I wanted to party, it was just that I didn’t want to feel anything at all because I felt so terrible. I didn’t want any of those feelings,” she recalls.It wasn't that she didn't try to break away, it was that she couldn't. She relapsed. A lot. And then she was confronted with one of those life moments in which she realized that her life could go one way or another. “I remember being in a hospital and thinking, 'I don’t want to die a statistic. I’m more than a statistic. I don’t want to die a statistic.' And I got arrested and that helped me get my life together because I don’t really want to go to jail,” Ashlynn said.She made milestones for herself. And eventually, became the person she is today, after finding what doctors call "medication assisted treatment," balanced with support groups and counseling. The first step though, says Dr. Adam Rubinstein, is making that call for help.“My concern is that because we’re all so focused on Covid-19 and it is so scary, patients with opioid use disorder who were already moving in the shadows may be even more marginalized,” Dr. Rubinstein said.Dr. Rubinstein works in both internal and addiction medicine. “We take care of people who have a disorder that hijacks their brain, people that are compulsively using a substance and can’t stop on their own," he said. The behaviors, he says, bring negative consequences. But those who suffer from the disease of addiction can't stop, and end up using so as to not suffer withdrawal.“They think they’ll die when they’re in withdrawal and will do anything they can to get out of it. Which means using that drug of choice again,” he said. The disease of addiction doesn't stop even in a global health crisis. The death rate from opioid overdoses is rising.“The second problem is that Covid-19 brings unemployment, financial problems, isolation and depression. Third, is our healthcare system is now less accessible,” Dr. Rubinstein explained.When we asked how the problem is addressed during a pandemic, Dr. Rubinstein said, “there is no one answer because addiction requires customization based on the provider and the patient deciding what is most effective.”As for Ashlynn, she wants people to know there's hope. And a way out. “I don’t regret what I went through, though, because it brought me to where I am today. I’m a different person than I was before I started using,” she said.It's never too early and never too late to start the road to recovery, Ashlynn says. For those who are ready to take the first step towards a new life, doctors recommend visiting www.samhsa.org and rethinkopioidaddiction.com 3400
The National Aeronautics and Space Administration says it will pay up to ,000 for lunar rocks from a company that will help mine the moon for resources.In a tweet, NASA Administrator Jim Bridenstine said that the agency is "buying lunar soil from a commercial provider! It’s time to establish the regulatory certainty to extract and trade space resources." 367
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