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 Two 250,000-year-old teeth from two Neanderthal children revealed that both of them were exposed to lead twice during their short lifetimes, the first known case of lead exposure in Neanderthals.An international team of researchers studied the two teeth, as well as one from a modern human child who lived 5,000 years ago. All of them are from the same archaeological site in southeast France. The results of their analysis were published Wednesday in the journal Science Advances."Traditionally, people thought lead exposure occurred in populations only after industrialization, but these results show it happened prehistorically, before lead had been widely released into the environment," said Christine Austin, study co-author and assistant professor in the Department of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai. "Our team plans to analyze more teeth from our ancestors and investigate how lead exposures may have affected their health and how that may relate to how our bodies respond to lead today."And as with tree rings, researchers used the teeth to determine key events in the children's lives. During childhood, new teeth layers are formed each day, capturing chemical signatures that can be traced."Teeth record environmental variation based on the climate, even where you're growing up," said Tanya Smith, lead author of the study and associate professor at Griffith University. "That's possible because when you're growing, your teeth you actually lock in a record of the chemistry of the water and the food that you're eating and drinking. Because teeth have these tiny timelines, we can relate the chemistry to the growth to calculate ancient climate records. We can't do that with any other element of the body."They were able to determine that one of the Neanderthal children was born in the spring and that both children were more likely to be sick during the colder winter seasons. They lived through more extreme seasons with a greater variation in temperature than the modern human child who was also studied.The intact teeth had growth rings, which the researchers used to measure barium, lead and oxygen. Lasers targeted tiny spots in the teeth to map their chemistry and reconstruct ancient climate records. This reconstruction was able to map a weekly scale of variation, showing when the summer and winter seasons happened and how long they lasted. The researchers related this back to the individual's growth."This study reports a major breakthrough in the reconstruction of ancient climates, a significant factor in human evolution, as temperature and precipitation cycles influenced the landscapes and food resources our ancestors relied on," Smith said.The growth rings also provided evidence of nursing."We were able to identify milk intake through breastfeeding in one individual based on a trace element called barium," Smith said. "We were able to time that to the season."That individual nursed for 2? years, which is similar to modern human children who lived in hunter-gatherer environments. "This is something we may share in common with Neanderthals," Smith said. Unfortunately, although the Neanderthal child survived infancy, it did not reach adulthood. The ages of the children were not included in the study.The researchers believe that the children were exposed to lead environmentally, either inhaling or ingesting it."That must have come from natural deposits in the area, whether they were going into an underground environment or they were eating contaminated food that was incorporated into their growing bones and teeth," Smith said.Smith believes that this research emphasizes the different levels of information that can be taken from teeth."We've now got the ability to integrate ancient climate data with health history, nursing history and illness," she said. "To be able to get all that information from a single sample 250,000 years ago is a unique opportunity."But this doesn't just apply to studying those who lived before us."Dietary patterns in our early life have far-reaching consequences for our health, and by understanding how breastfeeding evolved, we can help guide the current population on what is good breastfeeding practice," said Manish Arora, study co-author and vice chairman of the Department of Environmental Medicine and Public Health at the Icahn School of Medicine. "Our research team is working on applying these techniques in contemporary populations to study how breastfeeding alters health trajectories including those of neurodevelopment, cardiac health and other high-priority health outcomes." 4648

 American Apparel is coming back.Gildan Activewear, the Canadian company that owns the clothing brand, announced on Thursday that it will open a physical American Apparel store in Los Angeles this fall.American Apparel filed for bankruptcy in 2016. This will be the first location to open since May 2017, when Gildan finished liquidating the stores that were still open. Gildan is not planning to open others."We're treating this as a flagship pilot store," said Garry Bell, vice president of corporate marketing and communications for Gildan. He said the store will be "very experiential and very interactive," but did not provide details.The news was reported earlier by Bloomberg.Before the liquidation, American Apparel had 110 stores in the United States and a total of 193 locations worldwide, according to a court filing.Gildan, which also owns the tights brands Peds and Kushyfoot, purchased the American Apparel trademark after the company filed for bankruptcy. Then it relaunched American the brand online in the United States in August 2017.Several retail stores have recently declared bankruptcy as shoppers increasingly move online. Last year, US store closing announcements more than tripled and set a record, according to the retail think tank Fung Global Retail and Technology.Bon-Ton Stores, one of the country's largest department store companies, said in April that it plans to liquidate all 256 of its stores, which include Bon-Ton, Boston Store and Carson's. In March, Toys "R" Us said that it was closing all of its US stores.But American Apparel faced unique challenges. The company, which was known for its racy ads, fired its controversial founder and CEO, Dov Charney, twice in 2014 amid allegations of mismanagement and violations of the company's sexual harassment policies.The 2016 bankruptcy filing noted that "over the last two years, the company lacked a marketing plan and engaged in ad hoc advertising that lacked focus." 2003

"Black Bear" is a proudly weird film that shakes up the formula to the point that it explodes like a soda left in the fridge.The experimental film's fortunes rise and fall around the dryly comic talents of Aubrey Plaza, who delivers in a major way, exploring the playful cruelty she's subtly hinted at in many of her comedic roles.Plaza explores her dark side as Allison, a manipulative actress, and filmmaker who rents a home from Blair (Sarah Gordon) and her husband, Gabe (Christopher Abbott) to shoot a mysterious new project. She quickly inserts herself into their personal disputes, taking a sadistic pleasure in driving a wedge between the couple with subtle insults and provocations.Allison sees people as her playthings, and freely spins lies, half-truths, and seductive inferences, slithering in and out of suspicion, trust, hostility, and feigned kindness toward her mysterious goals. The interplay between Allison, Gabe, and Blair was enough to carry the movie, which would have been better suited had it stuck with the theme to its bitter end.Instead, the script flips just as the intensity level simmers.Writer/director Lawrence Michael Levine divides the film into two parts. The first is a captivating psychological game, but the second seems like a slew of barely-connected outtakes in which actors have swapped roles.While the scenes are often fascinating as they stand alone, they don't coalesce into much of a unified purpose. If the goal was to satirize the art of filmmaking or play with the quirks of the actor-director-writer dynamic, the result is a convoluted mess. Whatever inside jokes or buried subtext Levine were going for just doesn't translate.The title, which is no doubt some sort of opaque metaphor, also refers to a literal bear who just shows up, because, well, why not? Once Levine has stripped his project of any sense of cohesion, just about anything goes. If his goal was to show how a promising artistic project can derail, he succeeds too mightily.RATING: 2.5 stars out of 4.Phil Villarreal TwitterPhil Villarreal FacebookPhil Villarreal Amazon Author PagePhil Villarreal Rotten Tomatoes 2143

 It`s the one thing you don`t think will ever happen.A Cumberland County, Pennsylvania couple who wishes to remain anonymous went to the new Gilligan's location on Carslile Pike, only to come back home with the wrong Members First debit card."It was just crazy busy, and we went to pay, it took a little bit but we were understanding, we left not thinking anything of it," added receiver of wrong card.She says in the days following, she and her husband tried to use what they thought was their card for purchases, but it only worked once or twice before it started to decline."We kept putting the pin in and I was like I know my pin, I use it all the time, why isn`t this working?! And it just never dawned one me to check the name just because it looked like my card. Before it declined it, we were able to pump gas with this card," she added.That`s when she and her husband realized something was wrong."We looked down at the card and saw that it wasn`t our name on the card, same bank, same color card, same everything, just not our name," said receiver of wrong card.So they traced their steps back and found out Gilligan's Carlisle pike had their card and luckily, it had not been charged.But what about the money they accidentally charged on the other person's card?We`re trying to make it right and just pay that back the guy because it wasn`t our card, it`s not right," she said.Al Pioppo at the Members First headquarters in Cumberland County says they are doing the right thing."That`s fantastic that they did go the extra step and it makes our job a lot easier, we don`t have to file a dispute for the member and if we can make the other member whole that`s fantastic," said Al Pioppo, Vice President of card services at Members First.He says situations like these happen more often than not."Not everybody`s honest," said Pioppo.And there are things to keep in mind if it happens to you.First, call your bank."We can check into the account, we`ll notify the member and then we can shut down the card immediately so that it can`t be used by anybody," he added."I think it`s so important to be honest. It was an honest mistake and just to be upright, it`s the right thing to do," said receiver of wrong card. 2237

?? Some of you have been asking about the widespread radar returns the past few nights in #Vegas. Radar analysis suggests most of these echoes are biological targets. This typically includes birds, bats, and bugs, and most likely in our case--> Grasshoppers. ?? #VegasWeather pic.twitter.com/reQX7hJR7Y— NWS Las Vegas (@NWSVegas) July 27, 2019 359