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The first experimental COVID-19 vaccine in the U.S. is on track to begin a huge study next month to prove if it really can fend off the coronavirus, while hard-hit Brazil is testing a different shot from China.Where to do crucial, late-stage testing and how many volunteers are needed to roll up their sleeves are big worries for health officials as the virus spread starts tapering off in parts of the world.Moderna Inc. said Thursday the vaccine it is developing with the National Institutes of Health will be tested in 30,000 people in the U.S. Some will get the real shot and some a dummy shot, as scientists carefully compare which group winds up with the most infections.With far fewer COVID-19 cases in China, Sinovac Biotech turned to Brazil, the epicenter of Latin America’s outbreak, for at least part of its final testing. The government of S?o Paulo announced Thursday that Sinovac will ship enough of its experimental vaccine to test in 9,000 Brazilians starting next month.If it works, “with this vaccine we will be able to immunize millions of Brazilians,” said S?o Paulo′s Gov. Joao Doria.Worldwide, about a dozen COVID-19 potential vaccines are in early stages of testing. The NIH expects to help several additional shots move into those final, large-scale studies this summer, including one made by Oxford University that’s also being tested in a few thousand volunteers in Brazil.There’s no guarantee any of the experimental shots will pan out.But if all goes well, “there will be potential to get answers” on which vaccines work by the end of the year, Dr. John Mascola, who directs NIH’s vaccine research center, told a meeting of the National Academy of Medicine on Wednesday.Vaccines train the body to recognize a virus and fight back, and specialists say it’s vital to test shots made in different ways — to increase the odds that at least one kind will work.Sinovac’s vaccine is made by growing the coronavirus in a lab and then killing it. So-called “whole inactivated” vaccines are tried-and-true, used for decades to make shots against polio, flu and other diseases — giving the body a sneak peek at the germ itself — but growing the virus is difficult and requires lab precautions.The vaccine made by the NIH and Moderna contains no actual virus. Those shots contain the genetic code for the aptly named “spike” protein that coats the surface of the coronavirus. The body’s cells use that code to make some harmless spike protein that the immune system reacts to, ready if it later encounters the real thing. The so-called mRNA vaccine is easier to make, but it’s a new and unproven technology.Neither company has yet published results of how their shots fared in smaller, earlier-stage studies, designed to check for serious side effects and how well people’s immune systems respond to different doses.Even before proof that any potential vaccine will work, companies and governments are beginning to stockpile millions of doses so they can be ready to start vaccinating as soon as answers arrive.In the U.S., a program called “Operation Warp Speed” aims to have 300 million doses on hand by January. Under Brazil’s agreement with Sinovac, the Instituto Butantan will learn to produce the Chinese shot.___AP journalist Marcelo Silva de Sousa contributed to this report.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3499

The city of Asheville, North Carolina, released "disturbing, difficult to watch" videos from nine body-worn cameras related to the beating and tasing of a man who was suspected of jaywalking, the city said.One video from an officer on the scene shows Asheville police officer Christopher Hickman wrap his arms around the man's neck from behind as they attempt to subdue him.The footage provides greater insight into the August 2017 arrest of Johnnie Jermaine Rush, the man beaten, choked and tased by an Asheville police officer who suspected him of jaywalking.Hickman, 31, was removed from patrol duty a day after the incident. He resigned from the department in January, the same day that he was to be terminated, according to a timeline of the case released by the city council.Video of the arrest recorded by Hickman's body camera was published by the Asheville Citizen-Times on February 28, setting off outrage in the western North Carolina city. The newspaper has not revealed how it obtained the video.Hickman was taken into custody on March 8 and charged with one count each of assault by strangulation, assault inflicting serious injury and communicating threats, the city said.CNN telephoned and emailed Hickman's attorney on Monday afternoon but has not heard back from him.Nine videos releasedIn one of the videos taken after the use of force, Hickman speaks to a supervisor on the scene and admits to using the taser to punch the man in the face several times."I hit him in the face as if it was a club like three times. That was effective," Hickman says. "That's what happened to his left side, I punched him in the face with it about as hard as I could."A Buncombe County Superior Court Judge granted the city's petition to release the video, which was made public Monday at 2 p.m. The city asked to release the videos "in the interest of transparency," the city said on its website."This incident has created a loss of trust within the community, particularly among people of color. The City of Asheville understands that there is substantial work to do to restore the public's trust," the city said.Rush initially was charged with second-degree trespassing and resisting a public officer. He filed a complaint with police the day he was arrested alleging Hickman used excessive force.Police Chief Tammy Hooper watched the body camera footage and ordered Hickman off the street and told him to turn in his badge and gun, according to a timeline from the city.The district attorney and Asheville police agreed to dismiss the charges against Rush in September after watching the body camera footage, according to documents from the City Council.What Hickman's video showedThat video begins as Hickman and his partner stop Rush, then 32, for allegedly jaywalking in the early morning hours of August 25, 2017. After some initial words are exchanged, Hickman moves to arrest Rush, who then flees on foot."(He) thinks it's funny," Hickman is heard saying as he chases Rush. "You know what's funny is you're gonna get f---ed up hardcore."The officers catch Rush and tackle him to the ground. As Rush is being restrained on the ground, Hickman punches him in the head several times, shoots him with a stun gun and puts his hand around Rush's neck."I can't breathe! I can't breathe!" Rush repeatedly yells. "Help! Help!"Later in the video, Hickman speaks with another officer on the scene."I beat the s--- out of his head," Hickman says. "Not gonna lie about that."The ACLU of North Carolina was one of a number of organizations and residents that criticized the officer's actions."There is no excuse for what happened to Johnnie Rush," the ACLU of North Carolina said in a tweet. "Police must protect and serve everyone, regardless of race. Instead, a Black man gets beaten, tased, and choked over jaywalking. That's right, jaywalking."Asheville Mayor Esther Manheimer apologized last month to Rush in a statement on behalf of the City Council."The City Council and I immediately contacted city administration to express our outrage at the treatment of Mr. Rush and our outrage of not being informed about the actions of APD officers," Manheimer wrote. "We will have accountability and, above all, transparency." 4269

The Chicago Police Department announced that they arrested the mother of a 5-year-old girl who was stabbed to death on Saturday.CPD Superintendent David O. Brown announced the news during a press conference on Monday. 225

The Department of Labor reported Thursday that 1.5 million Americans filed initial claims for unemployment during the week ending June 13, bringing a 13-week total to about 45 million claims.Thursday's figures were down about 58,000 from last week's unemployment filings.Weekly claims for unemployment have been falling for nearly three straight months after peaking at about 6 million a week in late March. But weekly unemployment claims remain historically high.Prior to the pandemic, the record high for weekly unemployment claims came in 2006, when 665,000 people filed for unemployment. The Department of Labor has been tracking the statistics since 1967.Economists often use weekly unemployment claims as a reliable tool when predicting unemployment. However, some surveys indicate that initial weekly claims may be underestimating the amount of those unemployed.At least one survey from the Economic Policy Institute found that millions of Americans gave up trying to seek benefits or didn't even attempt to due to states' overwhelmed and antiquated unemployment systems.Until recently, the stock market has been on a steady rise since March despite the staggering unemployment numbers. However, fears of the virus's resurgence caused the market to fall 600 points last week before recovering slightly this week. 1327

The family of a 14-year-old Arizona boy with autism is demanding accountability after a Buckeye, Arizona police officer mistook the child for a drug user and detained him.On July 18, the boy, Connor Leibel, was forced to the ground by the officer and suffered multiple scrapes to his back, arm and face.The entire incident was captured on body camera, which was obtained by Scripps station ABC15. Watch the full raw video in the player above. Buckeye police officials did not immediately respond to requests for comment early Monday. In a statement by the Leibels' attorney, the family said they anguished over what happened and are demanding the city implement better training for its officers. “It’s astonishing that even after an internal investigation, the Buckeye Police Department claims it did absolutely nothing wrong,” the statement said. 861