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The US Food and Drug Administration has received 127 reports of seizures or other neurological symptoms possibly related to e-cigarettes, the agency announced Wednesday. Investigators have yet to determine, however, whether vaping was directly linked to the cases."The FDA is continuing its scientific investigation to determine if there's a direct relationship between the use of e-cigarettes and a risk of seizure or other neurological symptoms," said Dr. Ned Sharpless, the acting FDA commissioner.The FDA said the reported cases occurred between 2010 and 2019, and in addition to seizures, some people reported fainting or tremors. Sharpless said that "we still don't have enough information to determine if e-cigarettes are causing these reported incidents" but called on the public to continue submitting reports.Additional information "may help us identify common risk factors and determine whether any specific e-cigarette product attributes, such as nicotine content or formulation, may be more likely to contribute to seizures," he said.Dozens of new reports, no clear patternsIn April, the FDA announced that it had received 35 reports of seizures related to vaping, particularly among younger users. "Seizures or convulsions are known potential side effects of nicotine toxicity," the agency said at the time.There have been 92 new reports since then, but the FDA didn't announce any clear pattern across the cases.Cases were reported in both first-time and experienced e-cigarette users, and "seizures have been reported as occurring after a few puffs or up to one day after use," the FDA said in April. Several people had previously had a seizure diagnosis, the agency said at the time, and a few had also been using other drugs such as marijuana."Additional reports or more detailed information about these incidents are vital to help inform our analysis," Sharpless said Wednesday. Cases can be reported to the FDA 1943

The US Navy acknowledged Friday that a request had been made regarding the USS John S. McCain in relation to President Donald Trump's visit to Japan, but said the ship ended up remaining in its normal configuration.The statement continues a saga stemming from emails exchanged between the White House and lower-level US Navy officials about keeping a warship named for the late Sen. John McCain's father and grandfather out of sight ahead of the President's trip."A request was made to the U.S. Navy to minimize the visibility of USS John S. McCain, however, all ships remained in their normal configuration during the President's visit," Rear Adm. Charlie Brown, chief of Navy information, said in a statement. "There were also no intentional efforts to explicitly exclude Sailors assigned to USS John S. McCain."Brown added that the Navy is "fully cooperating with the review of this matter tasked by" acting Defense Secretary Patrick Shanahan.Two Navy officials told CNN on Wednesday that the White House Military Office had asked lower-level US Navy officials about keeping the ship out of view -- an impractical request as the ship was under repair, one of the officials said."Once leadership heard about it, they said knock it off," a senior Navy official told CNN.The ship ultimately was not moved nor was the name obscured, said Cmdr. Clay Doss, a spokesman for the 7th Fleet.Trump told reporters Thursday that while he had had no knowledge of the plan nor would he have acted on it, he "is not a big fan" of McCain, and whoever was behind the plan was "well-meaning."When asked abut the controversy Friday, Shanahan maintained that the military would not be politicized, adding that he would not have directed the ship to be moved."Our business is to run military operations and not to become politicized," Shanahan told reporters at a Singapore news conference. "I'll wait until I get a full explanation of the facts before I pass judgment on the situation, but our job is to run the military." 2016

The third Democratic primary debate, hosted by ABC and Univision, will take place on September 12.Presidential candidates had until late August to reach polling and grassroots fundraising thresholds 211

The Senate delivered a high-profile rebuke to President Donald Trump over his signature agenda issue Thursday when 12 Republicans joined Democrats to overturn the President's national emergency border declaration.The vote was 59-41, an overwhelming vote against the President's executive action.Lawmakers don't have enough votes, however, to override a certain veto from the President, but passage of the resolution in the Senate after it passed the House last month is nevertheless an embarrassing blow to Trump delivered by his own party over the President's top campaign pledge of a wall at the US-Mexico border.The setback for the President also comes on the heels of another high-profile break with his administration after the Senate 752

The US Food and Drug Administration announced Wednesday it is investigating a possible connection between e-cigarette use and seizures in younger users.In a public notice the agency reported "a recent uptick in voluntary reports of adverse experiences with tobacco products that mentioned seizures occurring with e-cigarette use (e.g., vaping)" signaling "a potential emerging safety issue."Since June 2018, the FDA said it has "observed a slight but noticeable increase in reports of seizures" connected with e-cigarette use."After examining poison control centers' reports between 2010 and early 2019, the FDA determined that, between the poison control centers and the FDA, there were a total of 35 reported cases of seizures mentioning use of e-cigarettes within that timeframe," the notice says. "Due to the voluntary nature of these case reports, there may be more instances of seizure in e-cigarette users than have been reported."FDA commissioner Dr. Scott Gottlieb released an accompanying statement explaining why the agency was releasing the information."We want to be clear that we don't yet know if there's a direct relationship between the use of e-cigarettes and a risk of seizure. We can't yet say for certain that e-cigarettes are causing these seizures," he said."We're sharing this early information with the public because as a public health agency, it's our job to communicate about potential safety concerns associated with the products we regulate that are under scientific investigation by the agency. This also helps encourage the public to voluntarily report additional adverse events that can better inform our work." 1656

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