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WASHINGTON, Dec. 12 (Xinhua) -- British scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. The findings, published Monday in the U.S. journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF -- the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.Scientists at the University of West England and the University of Bristol discovered that mutations in one specific cancer gene can control how splicing is balanced, allowing a master switch in the cell to be turned on. This master switch of splicing makes cancer cells grow faster, and blood vessels to grow more quickly, as they alter how VEGFs are put together.In experimental models, the researchers found that by using new drugs that block this master switch they prevented blood vessel growth and stopped the growth of cancers."The research clearly demonstrates that it may be possible to block tumor growth by targeting and manipulating alternative splicing in patients, adding to the increasingly wide armory of potential anti-cancer therapies," the authors said.
BALI, Indonesia, Nov. 19 (Xinhua) -- Chinese Premier Wen Jiabao said on Saturday that an immediate task for East Asian nations in the face of the global financial crisis was to maintain continuous, rapid development of the region's economy.Addressing the 6th East Asia Summit, Wen said East Asian nations should provide momentum for the world economy's robust, sustainable and balanced development."We should continue to strengthen cooperation and the summit should play a strategic role in this regard," he said.Wen put forward a five-point proposal for boosting the regional economy:First, coping with the international economic and financial crisis should continue to be regarded as a priority, he said.East Asian nations should implement appropriate fiscal and monetary policies in accordance with their national conditions, shore up market confidence, and enhance coordination in the macro-economic policy and financial cooperation.Second, Wen said the region should earnestly carry out and improve agreed free trade arrangements, steadily advance the building of new free trade areas, and further open markets.The Chinese premier called on East Asian nations to counter protectionism and properly handle international trade frictions.Third, the region should encourage expansion of investment and increase investor confidence, he said.It should boost the inner drive for its development through such ways as industrial transfer and regional interconnection, Wen said.Fourth, he called for prioritizing sustainable development as a long-term cooperative goal, stronger cooperation in key fields, help for East Asian countries to transform their economic development model, and intensified cooperation in such areas as energy-saving, environmental protection, education and disaster control, so as to enhance development potential.His final point urged overcoming challenges brought by non-traditional security threats to create a better environment for development, and strengthening cooperation in the fields of information exchange, capacity building and emergency response.Wen said that, as a strategic forum, the EAS facilitated mutual understanding and cooperation between East Asian nations."Under the new situation, we should continue to regard the Association of Southeast Asian Nations (ASEAN) as the dominant power of cooperation at the summit and make efforts to seek and expand interest junctions," he said.China was willing to work with all sides to make the summit more fruitful and benefit more countries and peoples, the Chinese premier said.Echoing Wen's remarks, participants at the summit said under the current international political and economic situation, East Asian cooperation should continue to wield the influence of ASEAN domination and the existing mechanism to intensify mutual support and coordination, and deepen cooperation in the fields of economy and trade, finance, food security, energy security and disaster relief.

LOS ANGELES, Oct. 3 (Xinhua) -- An organizer of the World Stem Cell Summit says one of the key problems medical researchers face these days is how to apply their findings in the real world."How do you take the phenomenal scientific research going on in labs and translate it into medical treatments,?" said Bernie Siegel, the founder and co-chair of the summit and executive director of the Genetic Policy Institute, which organized the event."It's a big job to do this, and more than just the science," Siegel said, noting that in a growing field now moving beyond basic lab research, the aim is to connect the people who do the work with those who finance it.The three-day summit, which opened Monday in Pasadena, features more than 150 top international speakers and 50 hours of programming with leaders from science, pharmaceutics, business, policy, ethics, law and other fields.The cell therapy industry, a "nascent" field, has emerged to be a potentially multi-billion business with unlimited potential, Siegel said.Stephen Dalton, a University of Georgia professor, reported that one of the biggest developments in stem cell research in the past year was the realization that cells can be transdifferentiated from one state to another without returning to a pluripotent state.Dalton said the principle was previously supported by a few isolated examples but it was not until 2010 that the idea was widely accepted.Mark Sussman, a professor from San Diego State University, called the identification of lung stem cells from human tissue samples capable of regenerating the highly complex and specialized structures of mature lungs a breakthrough in lung biology and regenerative medicine.He said results presented by the Anversa group in the New England Journal of Medicine demonstrate that human lung stem cells can be expanded in vitro and also retain the capacity to integrate into adult tissue upon introduction into mice.The study, Sussman said, has opened up an entirely new field of possibilities for lung regeneration and potential therapeutic applications for many conditions where treatment options are either very limited or nonexistent.
MINSK, Oct. 11 (Xinhua) -- Chinese telecommunications firm Huawei on Tuesday showcased its latest solutions in mobile broadband at an exhibition in Belarus.Focusing on the possibilities of expanding the capacity of mobile operators' networks, the solutions propose to use fourth-generation network standards and introduce elements of intelligent network resources.The exhibition also presented the latest generation of radios, transportation equipment, and terminal solutions."Mobile traffic is constantly increasing, but profit is not growing so fast - about 20 to 30 percent," Xu Zhidong, general director of Bel Huawei Technologies, said during the opening ceremony of the exhibition."We need to provide more services. In addition, the market should be presented by more terminal devices. The decisions, which are displayed at the exposition, will not only increase the volume of Internet traffic, but also increase average profit per subscriber," he added.Lu Guicheng, China's ambassador to Belarus, said Huawei has seen a very successful development, including in the Belarussian market.Huawei, China's largest telecommunications company, which began investing in Belarus in 2003, signed an agreement with the Eastern European nation last month to set up a network technology training center in Belarus for telecommunications technology research and training.It also agreed last month to help more than 300 Belarussian companies with their information technology construction over the next four years.
BEIJING, Jan. 24 (Xinhua) -- China's meteorological authority said Tuesday that the country's northern regions will continue to have sunny weather for the coming 24 hours, while the south will see subdued rain and snow.Temperatures in most parts of the country are expected to rebound slightly, the National Meteorological Center said in a statement on its website.But the lowest temperatures in the areas south of the Yangtze River will remain around zero degree Celsius, the center said.Meanwhile, rain and snow will subdue in most parts of the southern regions over the next three days, although freezing rain is forecast to hit Guizhou and Hunan provinces, according to the statement.
来源:资阳报