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The U.S. will pay more than billion for 100 million doses of a potential Covid-19 vaccine manufactured by Johnson & Johnson.The deal is one of several large agreements between the government and pharmaceutical companies as part of Operation Warp Speed, aimed at creating, testing, manufacturing and distributing a Covid-19 vaccine quickly.The Trump administration’s deal with Johnson & Johnson, announced Wednesday, allows for the purchase of an additional 200 million doses.Johnson & Johnson’s vaccine, developed by subsidiary Janssen Pharmaceutical Companies, has shown positive preclinical results. Testing of their vaccine is currently underway with human trials in the United States and Belgium.The Johnson & Johnson vaccine testing is reportedly behind some of the more advanced-stage potential vaccines, like those from Moderna, Pfizer and AstraZeneca, which have begun phase three human trials.“We greatly appreciate the U.S. government’s confidence in, and support for, our R&D platform and efforts and the scalability of our vaccine technology. We are scaling up production in the U.S. and worldwide to deliver a SARS-CoV-2 vaccine for emergency use,” said Paul Stoffels, M.D., Vice Chairman of the Executive Committee and Chief Scientific Officer, Johnson & Johnson in a statement.The company says they are committed to global access to the vaccine following approvals, and has a goal of supplying 1 billion doses globally through the end of 2021. 1493

The U.S. Marine Corps says it has lifted a "shelter-in-place" order at the Air Ground Combat Center (AGCC) in Twentynine Palms, California following earlier reports of an "active shooter."According to a statement from the Marines, the order was enacted when an "individual" suffered a self-inflicted gunshot wound on the base at about 8:30 a.m. PT. No other injuries were reported. The person who fired the gun has been transported to a local medical center for treatment.The Marines say they are investigating.Shortly after 8:30 a.m., the Marines tweeted that they were "aware of reports" of an active shooter at the AGCC. Later, both KESQ-TV in Palm Springs, California and KTTV-TV in Los Angeles reported — citing a base spokesperson — that a suspect had been taken into custody and that there were no reports of injuries. The Marines later disputed those reports, saying that it could not confirm that a suspect was in custody.The base is located about an hour's drive northwest of Palm Springs. 1008

The Trump Administration wants to change the definition of a showerhead to let more water flow, addressing a pet peeve of the president who complains he isn’t getting wet enough.Publicly talking about the need to keep his hair “perfect,” President Donald Trump has made increasing water flow and dialing back long held appliance conservation standards — from light bulbs to toilets to dishwashers — a personal issue.But consumer and conservation groups said the Department of Energy’s proposed loosening of a 28-year-old energy law that includes appliance standards is silly, unnecessary and wasteful, especially as the West bakes through a historic two-decade-long megadrought.Since 1992, federal law has dictated that new showerheads shouldn’t pour more than 2.5 gallons of water per minute (9.5 liters). As newer shower fixtures came out with multiple nozzles, the Obama administration defined the showerhead restrictions to apply to what comes out in total. So if there are four nozzles, no more than 2.5 gallons total should come out between all four.The new proposal Wednesday would allow each nozzle to spray as much as 2.5 gallons, not just the overall showerhead.With four or five or more nozzles, “you could have 10, 15 gallons per minute powering out of the showerhead, literally probably washing you out of the bathroom,” said Andrew deLaski, executive director of the energy conservation group Appliance Standards Awareness Project.On the White House South Lawn in July, Trump made the issue personal:“So showerheads — you take a shower, the water doesn’t come out. You want to wash your hands, the water doesn’t come out. So what do you do? You just stand there longer or you take a shower longer? Because my hair — I don’t know about you, but it has to be perfect. Perfect.”DeLaski and officials at Consumer Reports said there’s been no public outcry or need for change. The Department of Energy’s own database of 12,499 showerheads showed 74% of them use two gallons or less water per minute, which is 20% less than the federal standard.“Frankly it’s silly,” deLaski said. “The country faces serious problems. We’ve got a pandemic, serious long-term drought throughout much of the West. We’ve got global climate change. Showerheads aren’t one of our problems.”Energy Department spokeswoman Shaylyn Hynes said the 2013 Obama definition of showerhead clashes with what Congress intended and the standards of the American Society of Mechanical Engineers.If the rule is adopted, Hynes said it would be “allowing Americans — not Washington bureaucrats — to choose what kind of showerheads they have in their homes.”Officials at the industry group Plumbing Manufacturers International did not respond to a request for comment.Appliance and plumbing energy and water conservation standards save consumers about 0 a year on energy bills, deLaski said.If people are having trouble getting water flowing in their shower, they should check their home’s water pressure and can replace a faulty showerhead for not much money, deLaski said.A 2016 test of showerheads by Consumer Reports found that the best rated showerheads — including a model — provided a pleasing amount of water flow and met federal standards, according to David Friedman, a Consumer Reports vice president and former acting assistant energy secretary.DeLaski said he has had a hard time understanding the president’s shower concerns.“If the president needs help finding a good shower, we can point him to some great consumer websites that help you identify a good showerhead that provides a dense soak and a good shower,” deLaski said. 3624

The U.S. economy added 250,000 jobs in October, significantly exceeding expectations, the government announced Friday.The unemployment rate remained at 3.7 percent, a 49-year low. Wages grew 3.1 percent, strong growth after years of stagnant paychecks.The number will likely serve as a talking point for President Donald Trump and Congressional Republicans as they make closing arguments before the midterm elections next Tuesday.The year-over-year percentage growth in average hourly earnings looks larger than it actually is because wages declined last October as low-wage workers returned to their jobs following a particularly strong hurricane season. Month to month, hourly earnings increased by only five cents, a modest increase. 744

The University of Washington’s Institute for Health Metrics and Evaluation now projects that 67,000 American lives would be saved between now and December 1 by near universal wearing of masks.The IHME released the updated model on Thursday. As part of the update, the IHME said that four states, Arizona, Florida, Mississippi, and South Carolina, have hit an important metric of a daily death rate of eight per one million residents, and that those states should re-impose statewide closures of non-essential businesses.The IHME’s coronavirus projections have been frequently cited in the past by the White House’s coronavirus task force. The group uses state data along with other metrics to create projections on the number of coronavirus-related deaths throughout the US.The model projects with inconsistent use of masks, the US death toll for the coronavirus will be up to 295,000 by December 1, an increase from the current figure of 158,000, per Johns Hopkins University data. The IHME’s projections drops considerably to 228,000 if masks are worn universally outside of the home.IHME director Dr. Christopher Murray said at a news conference on Thursday that mask wearing mandates work, but communities also respond when they see cases are spreading.“People do respond to the circumstances in their community,” Murray said. “Mandates have an important effect.”One thing the model does not take into account is the use of therapeutics of a possible vaccine. Murray said that the IHME is closely monitoring the effectiveness of two potential therapeutics – remdesivir and dexamethasone – and may adjust future models as more is learned about those drugs.The model expects the number of coronavirus-related deaths to ebb and flow into the fall, but begin to increase by November. "November is a month we expect the spread to increase due to seasonality," Murray said. We are expecting considerable daily deaths. That pushes up our projections."“We expect it rise later in the fall,” Murray added.One cause for concern comes at the end of November when families begin to travel for holidays such as Thanksgiving.Murray said that while mask-wearing is not necessary when around family members of the same household, he said mask-wearing may be necessary for holiday gatherings. Murray said his family is taking the recommendation one step further, and is simply not gathering with extended relatives this fall.What’s built into the IHME’s projection is that a number of states will need to implement stricter closures in order to slow the spread. As part of the IHME’s recommendation, states implement closures of non-essential businesses when there is a threshold of eight deaths a day per million. Also part of the modeling is based on 50% of schools being closed in each state for the upcoming year. Murray said with many schools opening or implementing hybrid models, more will be learned in the coming weeks on how easily the virus spreads within schools.Recent measures in Arizona, California, Florida, and Texas has allowed a small decline in cases, but deaths in those states have not dropped off, according to Murray.“We have been seeing cases peaking and hospitalizations peaking and deaths not quite yet peaking, but we expect them to peak in the near future but we don’t expect a sharp decline," Murray said.To see a state-by-state breakdown of the IHME’s projections, click here. 3403