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武清区淋疾病寻龙济看
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发布时间: 2025-05-30 13:03:41北京青年报社官方账号
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  武清区淋疾病寻龙济看   

If you aren’t on this medication, chances are you know someone who is. It’s used to treat everything from pain to mood disorders and can be just what the doctor ordered for many.But now, there is mounting research uncovering misuse of and even a black market for this popular prescription.We’re talking about gabapentin. It’s approved for some types of seizures and nerve pain.Doctors also use it off-label to treat everything from insomnia to migraines to anxiety. Sixty-four million prescriptions of it were sold in the U.S. in 2016, up more than 60 percent from four years earlier.The thing is, experts say there is growing evidence it’s being abused, too. It’s even being sold on the streets under the name “Johnnys.” Dr. Joseph Insler, an addiction psychiatrist, says he’s seeing it all too often.“Sometimes, I've even experienced patients ask me for their “Johnnys” and then they'll, maybe, catch themselves and say, ‘No, no, no. I mean gabapentin',” he says.Why is this prescription being misused?“I think that some individuals may say that they use it to get high, and others may say they use it and get a drowsy effect. So, we're talking about the euphoria versus sedation, “ says Rachel Vickers Smith, Ph.D.Dr Vickers Smith wrote her dissertation on gabapentin abuse when studying drug abusers in Appalachia.“We found a nearly 3000 percent increase from 2008 to about 2014 in individuals reporting gabapentin abuse for the purposes of getting high,” she says.We wanted to see for ourselves, so we searched online. We easily found people talking about taking “Johnnys”, or gabapentin, to get high. There were also threads of people trying to spread awareness about the abuse.Experts say gabapentin is typically misused by substance abusers who mix it with other drugs.But, Dr. Insler says it’s also possible for people with legitimate prescriptions to misuse, too.He says, “If somebody’s taking excessively high doses or needing early refills” or if their mood changes, family members or clinicians should see these signs as red flags.A growing body of research shows the problem of abuse, especially among substance abusers is clear.  But some experts also worry about the number of prescriptions being handed out.A recent New England Journal of Medicine letter warned that “clinicians who are desperate for alternatives to opioids” are “increasingly prescribing gabapentin” and that “evidence suggests that some patients misuse, abuse or divert gabapentin.”Dr Rachel Vickers Smith says, “ I think that's why it's really important to get out the message,” about abuse, in general.Gabapentin is not a controlled substance or scheduled drug on the Federal level.We reached out to several government agencies. There was little information on potential abuse although the National Institute on Drug Abuse pointed us to existing research and the DEA says it is beginning to receive calls.Dr Vickers Smith says, “ I don't think that gabapentin abuse is on the CDC, DEA’s, NIDA’s radar, in part because we had this opioid epidemic.”All experts we talked to stress that this is NOT the next opioid epidemic, but they believe gabapentin abuse is something to watch closely and believe more research is needed.We contacted two of the manufacturers of gabapentin, including Pfizer, which told us, “Gabapentin is an important treatment option for their approved indications”. 3416

  武清区淋疾病寻龙济看   

If you're interested in fish who are scary-looking, poisonous and chock-full of elaborate defense mechanisms, look no further than the stonefish, a genus of fish that populate coastal waters of the Indo-Pacific region.As if their deadly venom and spiny exteriors weren't enough, scientists at the University of Kansas have found that stonefish also have a hidden switchblade on their face that they can flick out whenever they feel like they're in danger.Scientists call the bony, blade-like protrusion a "lachrymal saber," because it is located on a bone under the fish's eyes. Also, "lachrymal saber" is just a really metal-sounding name.William Leo Smith, associate curator and associate professor of ecology & evolutionary biology at KU, first started to understand how the lachrymal saber worked 15 years ago, when he was dissecting a stonefish he kept as a pet.This is a game-changerHe tells CNN the mechanism isn't just a cool new discovery (although it's that, too). It also changes the scientific understandings and classifications of this particular type of fish."It opens up these ideas of ecological questions. Muscular systems, bone systems, nervous systems all came together to form this. What led to its evolution or use?In other words, he says, "Why do we see this accumulation of so many horrible things on one fish?"The lachrymal saber is housed inside the fish's head, and they use their cheek muscles to deploy it. Though some stonefish are venomous, the saber is not.It could be a sex thing, tooSmith says he and his fellow researchers have reason to believe the saber isn't just for warding off predators: It could be a sex thing, too."There is evidence pushing towards that," he says. "They may use this in battles with other members of their species, like ram horns. It may also be involved in courtship behaviors."Oh, and the sabers glow."It's fluorescent green," Smith says. Since stonefish rely on camouflage for both protection and hunting prey, Smith doesn't think the fluorescence has a defensive purpose like, say, warning off predators.There are 134 described species of stonefish, and by Smith's observation, all of them have some form of lachrymal saber.  2202

  武清区淋疾病寻龙济看   

In advance of hurricane season, Florida Power and Light is reviewing plans to make sure power is restored quickly after a storm. This week the company is holding its annual storm drill, simulating a Category 3 hurricane. During the drill, the company says it is incorporating lessons learned from Hurricane Irma, which knocked out power to 6.7 million electrical customers, according to the U.S. Energy Information Administration (EIA).EIA reports the rate of electric service restoration following Hurricane Irma was faster than Hurricane Wilma in 2005. Five days after Irma’s landfall, the share of customers without power had fallen from a peak of 64 percent down to 18 percent -- a recovery rate of about 9 percent of customers per day.Power outages during Wilma declined from 36 percent of customers to 16 percent by the fifth day after landfall. This is an average recovery rate of about 4 percent of customers per day. FPL credits the improvement to money spent on infrastructure improvements. Since 2006, more than 860 main power lines were hardened; within the next five to seven years FPL wants to harden all of them.Strengthened power lines perform approximately 40 percent better than non-strengthened lines, FPL said.This year, FPL plans to undertake the following additional initiatives to improve the reliabilityof service: 1416

  

If you want to make money as an Uber driver but are put off by tales about drunk passengers, you can transport food instead of people with the company’s meal delivery service.Here’s a guide to how to get started as a delivery person for UberEats. 264

  

If you're on the hunt for a bike rack and can't find one, you're not alone. Bike racks are currently low stock, out of stock or backordered as bike sales soar amid the novel coronavirus pandemic.High demand for bike racks and installation is putting it lightly.“U-Haul is the number one installer of after-market hitches in the entire U.S., so we’ve got a hitch professional installing hitches, bike racks, trailer hitches, just about everything else you can imagine at almost all of our 2,000 company-owned stores, said Jeff Lockridge, with U-Haul International.“There’s enough customers asking for them to where the primary manufacturers have a backlog and that was the very reason that our hitch manager decided to expand our product line and go out and sign up more bike rack manufacturers to make sure we’ve got product quicker.”In fact, so many people want bike racks and hitches, June 2020 saw the biggest sales month in U-Haul’s 75-year history. Those June sales broke the May sales, which were also record-high. It also sent the U-Haul sales team looking for more companies to deliver more product.“We are understandably handcuffed a little bit by how quickly manufacturers can get product to us so that we can take care of our customers because people are wanting to get out and ride their bikes now,” Lockridge said.They expanded and now offering racks from 15 different companies.Also in high demand: U-Haul’s "contactless" system.“They can rent a truck, pick it up, entirely on their cell phone without having contact with our team members,” explained Lockridge. 1583

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