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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.

BEIJING, April 24 (Xinhua) -- The Chinese government has ordered food companies to keep clear and intact records of all their production and selling operations as part of the efforts to prevent the illegal use of food additives.All food manufacturing and management companies must examine all products in stock for any trace of illegal food additives and keep records of the results in accordance with laws and regulations, according to a circular released Sunday by the food safety committee under the State Council, or China's Cabinet.The circular came days after Vice Premier Li Keqiang warned of the great harm from illegal additives in food, promising "a firm attitude, iron-hand measures and more efforts" in dealing with the problem.Companies that fail to keep genuine and intact records and documents will be ordered to reform, and those providing fake records and certificates will be suspended from operations and punished accordingly, said the circular.According to the circular, it is strictly forbidden to produce and sell non-edible materials that are likely to be used in food production without official certificates, and authorized production companies of these materials must adopt a real-name selling system.These materials, including those banned in animal feed and drinking water, should not be sold to food and feed companies, the circular added.A series of food safety scandals emerged in China recently. In one of the latest cases, steamed buns in Shanghai were reported, last week, to have been dyed, sold past their expiration date, or laced with coloring additives to mislead consumers.

ROME, May 26 (Xinhua) -- African swine fever, a viral disease deadly to pigs but harmless to human beings, is spreading beyond Russia and the Caucasus region into Europe, the United Nations' food agency said Thursday."African swine fever is fast becoming a global issue," said Juan Lubroth, chief veterinary officer for the Food and Agriculture Organization."It now poses an immediate threat to Europe and beyond. Countries need to be on the alert and to strengthen their preparedness and contingency plans," he said.The disease, for which there is currently no vaccine, was introduced into Georgia from southern Africa late in 2006. It entered through the Black Sea port of Poti, where garbage from a ship was taken to a dump where pigs came to feed, the FAO said.Strategies to tackle African swine fever include quarantine, on-farm security and other measures aimed at minimizing the risk of introduction and establishing of the disease.

WASHINGTON, April 4 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) announced on Monday that following discussions among the International Space Station partners on Sunday, it is delaying the launch of space shuttle Endeavour's STS- 134 mission to April 29 from April 19.The new launch time is set for 3:47 p.m. EDT (1947 GMT) on Friday, April 29."The delay removes a scheduling conflict with a Russian Progress supply vehicle scheduled to launch April 27 and arrive at the station April 29," NASA said in a statement.NASA managers will hold a Flight Readiness Review on Tuesday, April 19, to assess the team's readiness to support launch. An official launch date will be selected at the conclusion of the meeting.Endeavour will deliver to the space station a 2-billion-dollar, multinational particle detector known as the Alpha Magnetic Spectrometer.

LOS ANGELES, March 2 (Xinhua) -- Those who take a nap are more likely to have lower levels of blood pressure despite stress, said a new study in the latest issue of International Journal of Behavioral Medicine available on Wednesday.In the study, researchers at Sarah Conklin of Allegheny College in Meadville, Pennsylvania examined 85 healthy university students, who were divided into two groups, with one group taking an hour- long nap during the day, and the other group having no time to sleep. Both groups were given a mental stress test.The study found that participants in both groups experienced increase in blood pressure and pulse rates when they took the stress test, but the average blood pressure of those who slept for at least 45 minutes was significantly lower after the stress test than it was for those who did not sleep.The researchers drew the conclusion that a daytime nap of at least 45 minutes may help stressed-out people lower their blood pressure and protect their heart."Our findings suggest that daytime sleep may offer cardiovascular benefit by accelerating cardiovascular recovery following mental stressors," the researchers said in the study."Further research is needed to explore the mechanism by which daytime sleep is linked with cardiovascular health and to evaluate daytime sleep as a recuperative and protective practice, especially for individuals with known cardiovascular disease risk and those with suboptimal sleep quality," they added.Sleep deficiency is common in the United States, posing a long- term health threat. On average, Americans get nearly two hours less sleep a night than they did 50 years ago, according to background information provided by the journal.

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