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LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283
KANSAS CITY, Mo. – After more than a century embedded beneath the paint, researchers discovered a grasshopper beneath the brushstrokes in a Vincent Van Gogh painting at the Nelson Atkins Art Museum.Paintings Conservator Mary Schafer discovered the tiny grasshopper in the lower foreground of the landscape while working under a microscope. It is not easily seen by the naked eye.Photo courtesy of the Nelson-Atkins. According to a news release from the Nelson, Schafer and other researchers hoped the grasshopper could be used to determine a more specific date on the painting.“It is not unusual to find insects or plant material in a painting that was completed outdoors,” Schafer said. “But in this case, we were curious if the grasshopper could be used to identify the particular season in which this work was painted.”Unfortunately, entomologists were unable to date the painting, but could determine the grasshopper had died before landing on Van Gogh’s canvas.Additional research on Van Gogh’s “Olive Trees” is underway. The painting is available for viewing at the Nelson Atkins Museum of Art in Kansas City, Missouri. 1144
Joe Biden’s campaign says the Democratic presidential nominee tested negative for coronavirus Sunday.The results come five days after Biden spent more than 90 minutes on the debate stage with President Donald Trump. The president was diagnosed with COVID-19 days after the debate, and he remains hospitalized.Biden had two negative tests on Friday, as well.Biden is scheduled to travel Monday to Florida. His campaign said it will continue to observe public health guidelines on masks, social distancing, and crowd sizes. 529
KANSAS CITY, Mo. — Priority Care Pediatrics in Kansas City requires its patients to follow the CDC immunization schedule.With the recent measles outbreak in the Kansas City area, the office made a post on Facebook to educate parents and reaction was swift.Dr. Raymond Cattaneo said that post, "Turned into something much bigger than that when some anti-vaccine people got a hold of that and bombarded our post. Reading comment after comment after comment you just kind of get worn down because you know you're fighting the good fight. You're on the right side of science but you worry that what they're saying, people will actually believe."Kristen Kleffner is a mom of four who got a letter from her son's school."We've done everything we can on our end but that doesn't necessarily mean they're still safe," Kleffner said. "You hear about measles outbreaks but you don't realize it's going to hit so close to home."Cattaneo told Scripps station KSHB in Kansas City, "Measles is one of the most contagious illnesses out there. It's a scary thing, especially when we know we have an immunization that can prevent this from happening."He added that it doesn't take many people for an outbreak to turn into an epidemic."The science is clear, this is about saving kids lives," Cattaneo said. 1301
JULIAN, Calif. (CNS) - A 63-year-old man died after crashing his pickup into a tree at an RV park near Julian, authorities said Wednesday.The crash happened about 6:40 p.m. Tuesday on KQ Ranch Road in the KQ Ranch RV resort, off state Route 79, California Highway Patrol Officer Travis Garrow said.The victim was driving a 2013 Ford F-150 pickup eastbound when, for unknown reasons, he drove off the north side of the road and slammed into a tree, Garrow said.Witnesses attempted to help the driver until medics arrived, but the man was pronounced dead before he could be airlifted to a hospital, the officer said.The driver's name was withheld pending family notification.Investigators determined that alcohol and/or drugs were suspected factors in the crash and the man was not wearing a seatbelt, Garrow said. 820