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MOSCOW, Aug. 24 (Xinhua) -- A Russian Progress cargo ship crashed into Siberia after failing to reach the right orbit Wednesday. The crash marked the second failure in space launch in less than a week and the third in this year, prompting local media to suspect a major reshuffle in Russia's space industry.UNPRECEDENTED FAILUREThe Progress M-12M unmanned freighter was launched to the International Space Station from Baikonur space center in Kazakhstan on Wednesday. It was expected to reach a near-Earth orbit in about nine minutes after launch.However, after the 325th second of the flight, which was just a few seconds before the vessel should reach the orbit, the ground control center lost it.Russian space agency Roscosmos confirmed later that the cargo ship failed to reach the orbit and fell down. Russian Progress M-12M cargo ship is launched to the International Space Station from Baikonur space center in Kazakhstan on Wednesday, Aug. 24, 2011. It has failed to reach the orbit, the Interfax news agency reported.The malfunction of the Soyuz-U rocket's engine was generally believed to be the cause of the accident, according to local media.A source in the space industry said the spaceship had sent a breakdown report while separating from the Soyuz rocket.Some unconfirmed reports said the fuel tank of the booster leaked and the engine was automatically turned off to avoid explosion.The wreckage of the Progress cargo ship has already fallen in southern Siberia's Altai Republic, where a big explosion was heard by locals, reported RIA Novosti news agency.A state investigation committee has been formed to look into the first ever loss of a Progress freighter.CONCERNS OVER FUTUREThe unprecedented accident raised concerns over the reserves of the six crew members on board the ISS.The ship was loaded with over 3.5 tons of supplies for the ISS, including scientific materials, oxygen, water and food.According to Russia's Ground Control, the loss of these supplies will not affect the ISS crew as there are enough stocks of necessities for two to three months.Also, there is no need for premature return of the crew, said Vladimir Solovyov, a space official.However, it still casts some shadow over the ISS program that relies on Russia exclusively following the retirement of U.S. shuttles.A source from the Russian space industry said the scheduled launches of the Soyuz rockets are likely to be suspended until the reasons of the accident are established.This means that current crew members of the ISS would likely stay longer in the space than planned, as the new members might not be able to replace them on schedule, the source explained. Solovyov said the launch of the next Progress is scheduled for October 28.So far, Roscosmos has refrained from comments regarding the possible halt in manned missions aboard Soyuz carrier rockets."Comments will follow. Now it is necessary to determine the causes of today's abortive launch of a Soyuz-u carrier rocket with the Progress M-2M transport ship," Roscosmos told Itar-Tass news agency.Local media raised the prospect of a major reshuffle in Russia' s space industry as the country has lost a total of six space vehicles over the past nine months.On Aug. 18, a carrier rocket Proton-M failed to deliver to the orbit communication satellite Express-AM4. Earlier in February, Russia had lost a satellite named Geo-IK2.In December 2010, a booster malfunction resulted in the loss of three satellites in the global positioning and navigation system GLONASS.

LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

Beijing, Sept. 6 (Xinhua) -- A sperm donation scandal disclosed recently has aroused growing concern in the United States.According to the New York Times' report, Ryan Kramer, the son of a donor, found that he has more than 150 half-siblings - they are all the children of the same donor."It's wild when we see them all together - they all look alike," said Cynthia Daily, mother of Kramer.As more women choose to have children on their own, the demand for sperm donors has surged.Some sperm banks are earning huge profits by allowing too many mothers to receive sperms from the same popular donors, according to the report.And this trend will lead to risks: rare genetic diseases could be spread more widely, and the children of the same donor could meet and, unbeknownst to them, commit incest, medical experts warned.Parents and donors are calling for a tighter regulation so that donor children can know more about their donors, and the number of kids from each donor can be limited.

HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.

BEIJING, Sept. 20 (Xinhua) -- Floods and landslides triggered by recent heavy rains in eight of China's provincial-level regions have left 70 people dead and 32 others missing this month.Heavy downpours, floods and other related disasters have affected Sichuan, Shaanxi, Henan, Chongqing, Hubei, Shandong, Shanxi and Gansu, the National Disaster Reduction Commission said in a statement released on Tuesday.As of Tuesday, these disasters have affected 21.56 million people and caused an estimated 26.09 billion yuan (4.08 billion U.S. dollars) in direct economic losses, the statement said.

来源：资阳报