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The creator of the Labradoodle cross-breed has said he inadvertently unleashed a "Frankenstein('s) monster."Wally Conron, 90, who worked for Guide Dogs Victoria in Australia when he bred the first Labrador-Poodle cross in 1989, spoke of his regrets at having begun a trend for designer breeds on an ABC podcast."I opened a Pandora's box and released a Frankenstein('s) monster," he said.His "big regret" is that his invention paved the way for "unethical, ruthless people" to breed the dogs without thinking of the health of their offspring.According to Conron, the majority of Labradoodles are "either crazy or have a hereditary problem," with healthy examples of the breed "few and far between."He believes that people have now gone too far with cross-breeding, which can increase a dog's risk of congenital disease, particularly down the generations. On the podcast, he laid particular scorn on the new Rottweiler-Poodle hybrid, known as a Rottle or a Rottie-Poo.Conron's original purpose in crossing a Labrador with a standard Poodle (which has a non-shedding coat) had been to provide a guide dog for a blind woman in Hawaii whose husband was allergic to dogs.The resulting litter of three was small, but one of the puppies did not trigger the husband's allergies and was sent to Hawaii to be her guide dog.As no one wanted the two remaining puppies, Conron asked the PR department at his work to spread the message of this new breed. Labradoodles quickly became popular in Australia and further afield.Now, designer breeds have become widespread -- but so has criticism of the consequences. Labradoodles, for example, can develop health problems common to Labrador Retrievers and Poodles such as hip dysplasia and eye disease.Colin Tennant, a British expert on dog behaviour with 45 years of experience in the industry, told CNN: "In essence, you are blindly breeding and altering genetics of the line without foreknowledge."Although Tennant said he doesn't have a problem with cross-breeding in general, he noted that breeders should pay more attention to dog's health.One example, he said, was the Bichon Frise, whose eyes water. "It must be in agony all the time," he explained. "They breed the face flat so they look humanoid because we find that attractive, with no consideration for the permutations we are producing with regards the dog's welfare or health." 2383

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The Florida man accused of sending mail bombs to CNN offices and prominent Democrats pleaded guilty on Thursday in Manhattan federal court to 65 felony counts, including using weapons of mass destruction in an attempted domestic terrorist attack.Cesar Sayoc, 57, admitted in court to having mailed 16 explosive devices to a variety of officials -- primarily Democrats, including former Presidents Barack Obama and Bill Clinton and Sens. Cory Booker and Kamala Harris; and major Democratic donors, including George Soros and Tom Steyer -- and to CNN's offices in October 2018.None of the devices detonated and no one was injured. After 647

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The fate of abortion in Missouri was to be argued in court Wednesday as Planned Parenthood fights the state for refusing to renew the license it needs to continue offering the service in its St. Louis clinic.That annual license expires on Friday, and without it, abortion services in Missouri will be no more -- making it the first state in more than 45 years to no longer offer the procedure.This does not mean that the health center will close. It will still provide care including birth control, STD testing and treatment, cancer screenings and more, explained Planned Parenthood spokeswoman Bonyen Lee-Gilmore. But the reality of what this would mean for abortion access is stark."This is not a drill. This is not a warning. This is a real public health crisis," Dr. Leana Wen, president and CEO of Planned Parenthood Federation of America, said in 865

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The Hubble Telescope can sure find some scary images of deep space in a video released by NASA on Monday. The images were of the twin galaxies AM 2026-424, which is a mere 724 million light-years away from Earth. That means the light we are seeing on Earth was emitted 724 million years ago.From Earth, the colliding galaxies appear to form the shape of a face, with two "eyes," which make up the core of the galaxies."Each 'eye' is the bright core of a galaxy, one of which slammed into another. The outline of the face is a ring of young blue stars. Other clumps of new stars form a nose and mouth," NASA said in a statement.""Although galaxy collisions are common¡ªespecially back in the young universe¡ªmost of them are not head-on smashups, like the collision that likely created this Arp-Madore system," NASA added. "The violent encounter gives the system an arresting 'ring' structure for only a short amount of time, about 100 million years. The crash pulled and stretched the galaxies' disks of gas, dust, and stars outward. This action formed the ring of intense star formation that shapes the nose and face." 1129

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The billionaires behind many of France's top luxury brands have pledged €300 million (9 million) to help reconstruct Paris' Notre Dame cathedral following a devastating fire.LVMH Group ( 201

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